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The protein encoded by IL16 is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. Additionally we are shipping Interleukin 16 Proteins (69) and Interleukin 16 Kits (68) and many more products for this protein.
Showing 10 out of 173 products:
Human Monoclonal IL16 Primary Antibody for FACS - ABIN2666009
Cruikshank, Little: lnterleukin-16: the ins and outs of regulating T-cell activation. in Critical reviews in immunology 2009
Show all 11 references for ABIN2666009
Human Monoclonal IL16 Primary Antibody for FACS - ABIN2662757
Gu, Lewis, Deere, Groome, Wang: Elevated maternal IL-16 levels, enhanced IL-16 expressions in endothelium and leukocytes, and increased IL-16 production by placental trophoblasts in women with preeclampsia. in Journal of immunology (Baltimore, Md. : 1950) 2008
Show all 11 references for ABIN2662757
Human Polyclonal IL16 Primary Antibody for EIA, IHC (p) - ABIN499974
Zhang, Center, Wu, Cruikshank, Yuan, Andrews, Kornfeld: Processing and activation of pro-interleukin-16 by caspase-3. in The Journal of biological chemistry 1998
Show all 4 references for ABIN499974
Human Polyclonal IL16 Primary Antibody for EIA, WB - ABIN499976
Cruikshank, Kornfeld, Center: Interleukin-16. in Journal of leukocyte biology 2000
Show all 4 references for ABIN499976
Human Monoclonal IL16 Primary Antibody for EIA, IHC (p) - ABIN111991
Kurschner, Yuzaki: Neuronal interleukin-16 (NIL-16): a dual function PDZ domain protein. in The Journal of neuroscience : the official journal of the Society for Neuroscience 1999
Show all 3 references for ABIN111991
Human Monoclonal IL16 Primary Antibody for EIA, WB - ABIN1107804
Cruikshank, Center, Nisar, Wu, Natke, Theodore, Kornfeld: Molecular and functional analysis of a lymphocyte chemoattractant factor: association of biologic function with CD4 expression. in Proceedings of the National Academy of Sciences of the United States of America 1994
intrathyroidal production of IL-14 (show TXLNA Antibodies) and IL-16 associated with the pathogenesis of autoimmune thyroid disease
the lack of a relationship between genotype and serum levels of IL-16 seems to suggest a more complex regulation of this cytokine at the post-translational level and/or the interplay with other cytokines.
The results suggested that the variants in IL-16 gene rs11556218 site were associated with a decreased knee osteoarthritis risk after adjusting for age, sex, BMI, and smoking and drinking status.
Data suggest that thymic stromal lymphopoietin (TSLP (show TSLP Antibodies)) and interleukin-16 (IL-16), expressed at early stages of disease, function to recruit malignant T cells to the skin.
Based on these results, we believe that the increased levels of IL-12p40 and IL-16 are associated with an ongoing inflammatory response in obese individuals and could lead to the development of disease conditions related to obesity.
The production of IL-16 contributed to lung damage as neutralization of IL-16 enhanced S. aureus clearance and resulted in diminished lung pathology in S. aureus pneumonia.
There was no statistical significance between IL12B (show IL12B Antibodies), IL16, and IL18 (show IL18 Antibodies) (rs187238) gene polymorphisms and kidney graft outcome after transplantation.
The findings suggest that the IL-16 rs 11556218 polymorphism may be used as a susceptibility marker for glioma.
IL-16 rs11556218 T/G was associated with a significant increased risk of cancer.
The rs11556218 T/G polymorphism of the IL-16 gene was significantly associated with elevated cancer risk in Asian populations. [meta-analysis]
Data indicate that knockdown of translocator protein TSPO (show TSPO Antibodies) by siRNAhad showed no effect on the productions of TNF-alpha (show TNF Antibodies), IL-1beta (show IL1B Antibodies) and IL-6 (show IL6 Antibodies) in lipopolysaccharide (LPS (show TLR4 Antibodies))-stimulated BV-2 microglia cells.
Interleukin-16 promotes cardiac fibrosis and myocardial stiffening in heart failure with preserved ejection fraction.
Data show overexpression of pro-IL-16 impaired resting B cell proliferation mediated through regulating nuclear factor (NF)-kappaB activation, and siRNA knock-down of pro-IL-16 expression decreased the level of p27(kip) and increased the level of Skp2.
We determined that ovalbumin (show OVA Antibodies) (OVA)-sensitized mice have an increase in systemic tumor necrosis factor-alpha (show TNF Antibodies) levels, and that serum or BAL fluid stimulation of bronchial epithelial cells results in production of IL-16
IL-16 induces a greater migratory response in the Th1 (show HAND1 Antibodies) cell subset than in the Th2 subset.
interleukin-16 and its precursor have roles in T lymphocyte activation and growth [review]
IL-16 precursor mRNA and protein expression are dynamically regulated during CD4 (show CD4 Antibodies)+ T cell activation by a calcineurin (show PPP3CA Antibodies)-dependent mechanism; pro-IL-16 may influence T cell cycle regulation, although not in a dominant manner.
Caspase-3 (show CASP3 Antibodies) mediated production of IL-16 by infiltrating CD4 (show CD4 Antibodies)+ T cells, contributes to ongoing neuroinflammation by chemoattraction of additional waves of CD4 (show CD4 Antibodies)+ T cells.
After femoral artery ligation, CD8 (show CD8A Antibodies)+ T cells infiltrate the site of collateral vessel growth and recruit CD4 (show CD4 Antibodies)+ mononuclear cells through the expression of IL-16
The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants.
, interleukin 16 (lymphocyte chemoattractant factor)
, lymphocyte chemoattractant factor
, neuronal interleukin 16
, prointerleukin 16