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Interleukin 27 Proteins (IL27)

The protein encoded by IL27 is one of the subunits of a heterodimeric cytokine complex. Additionally we are shipping IL27 Antibodies (150) and IL27 Kits (43) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IL27 53342 Q8TAD2
IL27 246779 Q8K3I6
IL27 365368  
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Top IL27 Proteins at

Showing 10 out of 27 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_CHO Cells Human His tag 10 μg Log in to see 16 Days
HOST_Human Cells Mouse His tag 10 μg Log in to see 16 Days
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
HOST_Escherichia coli (E. coli) Rat His tag 100 μg Log in to see 11 to 13 Days
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   1 mg Log in to see 2 to 3 Days
HOST_HEK293 Human Un-conjugated   10 μg Log in to see 3 to 4 Days
Rat Mouse Un-conjugated   1 set Log in to see 4 to 6 Days

IL27 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
Mouse (Murine) , , , ,

Rat (Rattus)

Top referenced IL27 Proteins

  1. Mouse (Murine) IL27 Protein expressed in Human Cells - ABIN2008620 : Pflanz, Timans, Cheung, Rosales, Kanzler, Gilbert, Hibbert, Churakova, Travis, Vaisberg, Blumenschein, Mattson, Wagner, To, Zurawski, McClanahan, Gorman, Bazan, de Waal Malefyt, Rennick, Kastelein: IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells. in Immunity 2002 (PubMed)
    Show all 5 references for ABIN2008620

  2. Human IL27 Protein expressed in CHO Cells - ABIN2002020 : Fakruddin, Lempicki, Gorelick, Yang, Adelsberger, Garcia-Pineres, Pinto, Lane, Imamichi: Noninfectious papilloma virus-like particles inhibit HIV-1 replication: implications for immune control of HIV-1 infection by IL-27. in Blood 2007 (PubMed)
    Show all 5 references for ABIN2002020

  3. Human IL27 Protein expressed in Wheat germ - ABIN1307800 : Di Meo, Airoldi, Sorrentino, Zorzoli, Esposito, Di Carlo: Interleukin-30 expression in prostate cancer and its draining lymph nodes correlates with advanced grade and stage. in Clinical cancer research : an official journal of the American Association for Cancer Research 2014 (PubMed)
    Show all 2 references for ABIN1307800

More Proteins for Interleukin 27 (IL27) Interaction Partners

Human Interleukin 27 (IL27) interaction partners

  1. this study shows that the serum levels of IL-27 are lower in Iranian diabetes type I patients compared to the healthy individuals

  2. our findings showed a relationship between the IL-27 2905T/G genotype variant and the decreased susceptibility for developing cervical cancer. The IL-27 2905T/G genotype variant also modified the survival time in cervical cancer patients.

  3. an IL-27/Stat3 (show STAT3 Proteins) axis induces expression of programmed cell death 1 (show PDCD1 Proteins) ligands (PD-L1 (show CD274 Proteins)/2) on infiltrating macrophages in lymphoma

  4. Interleukin-27 rs 153109 Single Nucleotide Polymorphism is associated with responses to therapy in Hepatitis C.

  5. this study shows that IL-27 gene polymorphism is genetic risk factor for systemic lupus erythematosus in the Polish population, and that it predicts disease phenotype

  6. Data indicate that the CC genotype of interleukin 27 (IL-27) single nucleotide polymorphism rs153109 was significantly more prevalent in pre-eclampsia (PE) cases than controls.

  7. IL-27 is a viable candidate biomarker to identify bacterial infection among ED patients and is comparable with PCT (show UROD Proteins).

  8. The inhibition of Th17 cells by IL-27 is vital for the maintenance of the feto-maternal tolerance and the prevention of lupus, multiple sclerosis, autoimmune uveitis, immune thrombocytopenia and atherosclerosis

  9. Our results showed that the IL-27 2905T/G genotypes were associated with decreased the susceptibility and development of cervical cancer in Chinese Han population.

  10. the genetic polymorphisms of IL-27 rs153109 and rs181206 may be involved in the progression of human cancers and diseases.

Mouse (Murine) Interleukin 27 (IL27) interaction partners

  1. An IL-27/Lag3 (show LAG3 Proteins) axis enhances Foxp3 (show FOXP3 Proteins)+ regulatory T cell-suppressive function and therapeutic efficacy.

  2. IL-27 is one of the limited unique cytokines directly acting on hematopoietic stem cells (HSCs) to promote differentiation into myeloid progenitors during emergency myelopoiesis.

  3. These results provide the first evidences that Fli-1 (show FLI1 Proteins) positively regulates LPS (show TLR4 Proteins)-induced IL-27 production in macrophages

  4. of autocrine/paracrine mechanisms involving IL-27 in adipocytes under conditions of inflammatory stress that may link obesity with inflammatory diseases.

  5. Increased IL-27 expression in bleomycin-induced pulmonary fibrosis was noted.

  6. IL-27 induces the endothelial differentiation in cardiac resident stem cells through STAT3 (show STAT3 Proteins)/Pim-1 (show PIM1 Proteins) signaling pathway.

  7. demonstrate that suppression mediated by interferon (show IFNA Proteins) and IL-27 is a negative feedback mechanism for group 2 innate lymphoid cells function in vivo

  8. Natural killer cells-dendritic cells interaction elicits a positive feedback loop for IFN-gamma (show IFNG Proteins) and IL-27 production.

  9. demonstrate the essential role of IL-27 signaling in regulating immune responses to extracellular protozoan infections

  10. IL-27 regulates enhanced susceptibility to S. aureus pneumonia following influenza infection, potentially through the induction of IL-10 (show IL10 Proteins) and suppression of IL-17 (show IL17A Proteins).

Pig (Porcine) Interleukin 27 (IL27) interaction partners

  1. The open reading frame of IL-27 p28 gene is 720 bp, which encodes a protein of 239 amino acids with a predicted molecular mass of 26.6 kDa. The deduced amino acid sequence of IL-27 p28 showed a high degree of homology to human (63%) and mouse (58%).

IL27 Protein Profile

Protein Summary

The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).

Gene names and symbols associated with Interleukin 27 Proteins (IL27)

  • interleukin 27 (IL27)
  • interleukin 17D (IL17D)
  • interleukin 27 (Il27)
  • interleukin 27-like (LOC100349321)
  • IL-17D protein
  • IL-22 protein
  • IL-27 protein
  • IL-27A protein
  • IL-27p28 protein
  • IL27 protein
  • IL27A protein
  • IL27p28 protein
  • Il30 protein
  • p28 protein
  • RGD1561420 protein

Protein level used designations for Interleukin 27 Proteins (IL27)

interleukin 27 , interleukin-17D , interleukin-27 , IL-27 p28 subunit , IL-27 subunit alpha , IL-27-A , IL27-A , interleukin 30 , interleukin-27 subunit alpha , interleukin 27 p28 subunit , p28 , interluekin 27

737725 Pan troglodytes
53342 Homo sapiens
246778 Homo sapiens
246779 Mus musculus
365368 Rattus norvegicus
100724612 Cavia porcellus
493187 Sus scrofa
607880 Canis lupus familiaris
614927 Bos taurus
101122495 Ovis aries
101093822 Felis catus
100349321 Oryctolagus cuniculus
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