Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
The protein encoded by IL27 is one of the subunits of a heterodimeric cytokine complex. Additionally we are shipping IL27 Antibodies (143) and IL27 Kits (49) and many more products for this protein.
Showing 10 out of 27 products:
Mouse (Murine) IL27 Protein expressed in Human Cells - ABIN2008620
Pflanz, Timans, Cheung, Rosales, Kanzler, Gilbert, Hibbert, Churakova, Travis, Vaisberg, Blumenschein, Mattson, Wagner, To, Zurawski, McClanahan, Gorman, Bazan, de Waal Malefyt, Rennick, Kastelein: IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells. in Immunity 2002
Show all 5 references for ABIN2008620
Human IL27 Protein expressed in CHO Cells - ABIN2002020
Fakruddin, Lempicki, Gorelick, Yang, Adelsberger, Garcia-Pineres, Pinto, Lane, Imamichi: Noninfectious papilloma virus-like particles inhibit HIV-1 replication: implications for immune control of HIV-1 infection by IL-27. in Blood 2007
Show all 5 references for ABIN2002020
Human IL27 Protein expressed in Wheat germ - ABIN1307800
Di Meo, Airoldi, Sorrentino, Zorzoli, Esposito, Di Carlo: Interleukin-30 expression in prostate cancer and its draining lymph nodes correlates with advanced grade and stage. in Clinical cancer research : an official journal of the American Association for Cancer Research 2014
Show all 2 references for ABIN1307800
The Serum IL-27 levels were negatively correlated with neuromyelitis optica spectrum disorders severity and spinal cord lesion length.
IL-27 gene rs153109 A/G SNP may be involved in susceptibility to BD in the Iranian population.
Serum IL-27 and IL-27-producing T cells, are involved in the pathogenesis of pemphigus.
The level of interleukin 27 is increased in peripheral blood mononuclear cells of patients with rheumatoid arthritis or osteoarthritis.
role of IL-27 in inflammation, cancer development and regulation and differentiation of immune cells.
The B cell response to IL-27 is modulated during B cell differentiation and varies depending on the mode of B cell activation (show BLNK Proteins).
data showed that progressive MS patients had decreased plasma and mRNA expression levels of IL-27, suggesting that it might be involved in the pathophysiological process of multiple sclerosis
The rs153109 and rs17855750 IL-27 polymorphisms were associated with increased risk for renal cell carcinoma (show MOK Proteins), suggesting an important role of IL-27 in nephrocarcinogenesis.
The results of the present study clearly demonstrate that the STAT3 (show STAT3 Proteins) pathway triggered by anti-inflammatory IL-27 plays a role in protecting cardiomyocytes against GSC (show GSC Proteins)-mediated damage.
study shows that IL-27 rs17855750 polymorphism is significantly associated with increased susceptibility to cancer in Chinese
IL-27 is one of the limited unique cytokines directly acting on hematopoietic stem cells (HSCs) to promote differentiation into myeloid progenitors during emergency myelopoiesis.
These results provide the first evidences that Fli-1 (show FLI1 Proteins) positively regulates LPS (show TLR4 Proteins)-induced IL-27 production in macrophages
of autocrine/paracrine mechanisms involving IL-27 in adipocytes under conditions of inflammatory stress that may link obesity with inflammatory diseases.
Increased IL-27 expression in bleomycin-induced pulmonary fibrosis was noted.
IL-27 induces the endothelial differentiation in cardiac resident stem cells through STAT3 (show STAT3 Proteins)/Pim-1 (show PIM1 Proteins) signaling pathway.
demonstrate that suppression mediated by interferon (show IFNA Proteins) and IL-27 is a negative feedback mechanism for group 2 innate lymphoid cells function in vivo
Natural killer cells-dendritic cells interaction elicits a positive feedback loop for IFN-gamma (show IFNG Proteins) and IL-27 production.
demonstrate the essential role of IL-27 signaling in regulating immune responses to extracellular protozoan infections
IL-27 regulates enhanced susceptibility to S. aureus pneumonia following influenza infection, potentially through the induction of IL-10 (show IL10 Proteins) and suppression of IL-17 (show IL17A Proteins).
These data identify an IL-27/NFIL3 (show NFIL3 Proteins) signalling axis as a key regulator of effector T-cell responses via induction of Tim-3 (show HAVCR2 Proteins), IL-10 (show IL10 Proteins) and T-cell dysfunction.
The open reading frame of IL-27 p28 gene is 720 bp, which encodes a protein of 239 amino acids with a predicted molecular mass of 26.6 kDa. The deduced amino acid sequence of IL-27 p28 showed a high degree of homology to human (63%) and mouse (58%).
The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).
, IL-27 p28 subunit
, IL-27 subunit alpha
, interleukin 30
, interleukin-27 subunit alpha
, interleukin 27 p28 subunit
, interluekin 27