IL-10 Proteins
(Interleukin 10 (IL10))
The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011].
| Catalog no. | Product | Reactivity | Host / Clonality | Application | Price & lead time |
|---|---|---|---|---|---|
| IL-10 Protein (AA 19-178) (Biotin,His-Avi Tag) | Human | HEK-293 Cells |
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$811.67
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| IL-10 Protein (AA 19-178) (His-Avi Tag) | Human | HEK-293 Cells |
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$522.92
View price
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| IL-10 Protein (AA 19-178) | Human | CHO Cells |
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$419.65
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| IL-10 Protein (AA 19-178) (His tag) | Human | HEK-293 Cells |
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$834.60
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| IL-10 Protein (AA 22-178) (His tag) | Hamster | Escherichia coli (E. coli) |
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$449.07
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| IL-10 Protein (AA 19-178) | Human | Mammalian Cells |
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$449.07
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| IL-10 Protein (AA 19-178) (His tag) | Rat | Escherichia coli (E. coli) |
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$449.07
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| IL-10 Protein (AA 19-178) (His tag) | Mouse | Escherichia coli (E. coli) |
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$658.46
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| IL-10 Protein (AA 1-178) (GST tag) | Human | Wheat germ |
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$475.39
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| IL-10 Protein (AA 19-178) (His tag) | Mouse | Escherichia coli (E. coli) |
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$721.18
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| IL-10 Protein (His tag) | Human | Escherichia coli (E. coli) |
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$2,386.92
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| IL-10 Protein | Mouse | Escherichia coli (E. coli) |
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$126.00
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| IL-10 Protein (AA 19-178) (His tag) | Mouse | Mammalian Cells |
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$535.66
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| IL-10 Protein (AA 19-178) (Fc Tag) | Human | CHO Cells |
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$409.69
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| IL-10 Protein (AA 19-178) (His tag) | Human | HEK-293 Cells |
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$275.99
View price
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| IL-10 Protein (AA 19-178) | Human | Escherichia coli (E. coli) |
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$275.99
View price
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| IL-10 Protein (His tag) | Mouse | HEK-293 Cells |
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$533.50
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| IL-10 Protein (AA 1-178, Extracellular Domain, N-Term) (Fc Tag) | Mouse | CHO Cells |
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$733.13
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| IL-10 Protein (AA 19-178, C-Term) (His tag) | Human | HEK-293 Cells |
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$388.13
View price
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| IL-10 Protein (AA 19-178, N-Term) (His tag) | Human | Escherichia coli (E. coli) |
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$388.13
View price
|
Protein
- SDS (SDS-PAGE: Validation image available)
- SPR (Surface Plasmon Resonance: Validation image available)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: Validation image available)
- Origin
- Human
- Host
- HEK-293 Cells
- Protein Type
- Recombinant
- Purity
- > 95 % as determined by Bis-Tris PAGE
- Biological Activity
- Active
Catalog No. ABIN7274897
$811.67
Plus shipping costs $50.00
100 μg
(More quantities available)
Shipping to:
United States
Delivery in 11 to 14 Business Days
Protein
- SDS (SDS-PAGE: Validation image available)
- SPR (Surface Plasmon Resonance: Validation image available)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: Validation image available)
- Origin
- Human
- Host
- HEK-293 Cells
- Protein Type
- Recombinant
- Purity
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- Biological Activity
- Active
Catalog No. ABIN7274896
$522.92
Plus shipping costs $50.00
100 μg
(More quantities available)
Shipping to:
United States
Delivery in 3 to 6 Business Days
Protein
- SDS (SDS-PAGE: Validation image available)
- AcA (Activity Assay: Validation image available)
- Origin
- Human
- Host
- CHO Cells
- Protein Type
- Recombinant
- Purity
- > 95 % as analyzed by SDS-PAGE and HPLC.
- Biological Activity
- Active
Catalog No. ABIN2018051
$419.65
Plus shipping costs $50.00
50 μg
(More quantities available)
Shipping to:
United States
Delivery in 2 to 4 Business Days
Protein
- SDS (SDS-PAGE: Validation image available)
- ADA (Antibody Drug Assay: Listed application)
- AM (Affinity Measurement: Listed application)
- IA (Immunoassay: Listed application)
- ScA (Screening Assay: Listed application)
- Origin
- Human
- Host
- HEK-293 Cells
- Protein Type
- Recombinant
- Purity
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN7491255
$834.60
Plus shipping costs $50.00
100 μg
(More quantities available)
Shipping to:
United States
Delivery in 12 to 15 Business Days
Protein
- WB (Western Blotting: Validation image available)
- ELISA (ELISA: Listed application)
- Origin
- Hamster
- Host
- Escherichia coli (E. coli)
- Protein Type
- Recombinant
- Purity
- Greater than 90 % as determined by SDS-PAGE.
Catalog No. ABIN7123537
$449.07
Plus shipping costs $50.00
50 μg
(More quantities available)
Shipping to:
United States
Delivery in 13 to 17 Business Days
Protein
- WB (Western Blotting: Validation image available)
- ELISA (ELISA: Listed application)
- Origin
- Human
- Host
- Mammalian Cells
- Protein Type
- Recombinant
- Purity
- Greater than 90 % as determined by SDS-PAGE.
Catalog No. ABIN7123538
$449.07
Plus shipping costs $50.00
50 μg
(More quantities available)
Shipping to:
United States
Delivery in 13 to 17 Business Days
Protein
- WB (Western Blotting: Validation image available)
- ELISA (ELISA: Listed application)
- Origin
- Rat
- Host
- Escherichia coli (E. coli)
- Protein Type
- Recombinant
- Purity
- Greater than 90 % as determined by SDS-PAGE.
- Biological Activity
- Active
Catalog No. ABIN7123541
$449.07
Plus shipping costs $50.00
50 μg
(More quantities available)
Shipping to:
United States
Delivery in 13 to 17 Business Days
Protein
- WB (Western Blotting: Validation image available)
- ELISA (ELISA: Listed application)
- Origin
- Mouse
- Host
- Escherichia coli (E. coli)
- Protein Type
- Recombinant
- Purity
- Greater than 90 % as determined by SDS-PAGE.
- Biological Activity
- Active
Catalog No. ABIN7123540
$658.46
Plus shipping costs $50.00
50 μg
(More quantities available)
Shipping to:
United States
Delivery in 13 to 17 Business Days
Protein
- AP (Affinity Purification: Listed application)
- AA (Antibody Array: Listed application)
- ELISA (ELISA: Listed application)
- WB (Western Blotting: Listed application)
- Origin
- Human
- Host
- Wheat germ
- Protein Type
- Recombinant
Catalog No. ABIN1307664
$475.39
Plus shipping costs $50.00, if applicable $20.00 dry ice
10 μg
(More quantities available)
Shipping to:
United States
Delivery in 11 to 14 Business Days
Protein
- WB (Western Blotting: Validation image available)
- CC (Cell Culture: Listed application)
- Origin
- Mouse
- Host
- Escherichia coli (E. coli)
- Protein Type
- Recombinant
- Purity
- > 98 % as determined by reducing SDS-PAGE.
- Biological Activity
- Active
Catalog No. ABIN7320571
$721.18
Plus shipping costs $50.00
100 μg
(More quantities available)
Shipping to:
United States
Delivery in 11 to 15 Business Days
Protein
- SDS (SDS-PAGE: Validation image available)
- WB (Western Blotting: Listed application)
- Grade
- GMP Grade
- Origin
- Human
- Host
- Escherichia coli (E. coli)
- Protein Type
- Recombinant
- Purity
- >98 %
- Biological Activity
- Active
Catalog No. ABIN7884438
$2,386.92
Plus shipping costs $50.00
100 μg
Shipping to:
United States
Delivery in 10 to 15 Business Days
Protein
- AcA (Activity Assay: Validation image available)
- Func (Functional Studies: Listed application)
- Origin
- Mouse
- Host
- Escherichia coli (E. coli)
- Protein Type
- Recombinant
- Purity
- >95 % as determined by SDS-PAGE
Catalog No. ABIN5509335
$126.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 11 to 22 Business Days
Protein
- SDS (SDS-PAGE: Listed application)
- WB (Western Blotting: Listed application)
- Imm (Immunogen: Listed application)
- ELISA (ELISA: Listed application)
- AcA (Activity Assay: Listed application)
- Origin
- Mouse
- Host
- Mammalian Cells
- Protein Type
- Recombinant
- Purity
- >90 % as determined by SDS-PAGE.
- Biological Activity
- Active
Catalog No. ABIN7678419
$535.66
Plus shipping costs $50.00
100 μg
(More quantities available)
Shipping to:
United States
Delivery in 12 to 15 Business Days
Protein
- Origin
- Human
- Host
- CHO Cells
- Protein Type
- Recombinant
- Purity
- >98 % (SDS-PAGE)
Catalog No. ABIN6253270
$409.69
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 5 to 10 Business Days
Protein
- Origin
- Human
- Host
- HEK-293 Cells
- Protein Type
- Recombinant
Catalog No. ABIN7889184
$275.99
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 5 Business Days
Protein
- Origin
- Human
- Host
- Escherichia coli (E. coli)
- Protein Type
- Recombinant
Catalog No. ABIN7889185
$275.99
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 5 Business Days
Protein
- Origin
- Mouse
- Host
- HEK-293 Cells
- Protein Type
- Recombinant
- Purity
- > 90 % by SDS-PAGE.
- Biological Activity
- Active
Catalog No. ABIN7520137
$533.50
Plus shipping costs $50.00
100 μg
(More quantities available)
Shipping to:
United States
Delivery in 7 to 10 Business Days
Protein
- Origin
- Mouse
- Host
- CHO Cells
- Protein Type
- Recombinant
- Purity
- >98 % (SDS-PAGE)
- Biological Activity
- Active
Catalog No. ABIN7278731
$733.13
Plus shipping costs $50.00
50 μg
(More quantities available)
Shipping to:
United States
Delivery in 5 to 10 Business Days
Protein
- Origin
- Human
- Host
- HEK-293 Cells
- Protein Type
- Recombinant
- Purity
- >95 % (SDS-PAGE)
- Biological Activity
- Active
Catalog No. ABIN6253266
$388.13
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 5 to 10 Business Days
Protein
- Origin
- Human
- Host
- Escherichia coli (E. coli)
- Protein Type
- Recombinant
- Purity
- >95 % (SDS-PAGE)
Catalog No. ABIN6253267
$388.13
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 5 to 10 Business Days
Latest Publications for our IL-10 Proteins
: "Suppression of human B cell activation by 2,3,7,8-tetrachlorodibenzo-p-dioxin involves altered regulation of B cell lymphoma-6." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 144, Issue 1, pp. 39-50, (2015) (PubMed).
: "Chronic helminth infection reduces basophil responsiveness in an IL-10-dependent manner." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 188, Issue 9, pp. 4188-99, (2012) (PubMed).
: "Recombinant protein yield in rice seed is enhanced by specific suppression of endogenous seed proteins at the same deposit site." in: Plant biotechnology journal, Vol. 10, Issue 9, pp. 1035-45, (2012) (PubMed).
: "NF?B activation and stimulation of chemokine production in normal human macrophages by the gadolinium-based magnetic resonance contrast agent Omniscan: possible role in the pathogenesis of ..." in: Annals of the rheumatic diseases, Vol. 69, Issue 11, pp. 2024-33, (2010) (PubMed).
: "Circulating myeloid dendritic cells of advanced cancer patients result in reduced activation and a biased cytokine profile in invariant NKT cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 11, pp. 7287-93, (2008) (PubMed).
: "Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies." in: Journal of immunological methods, Vol. 188, Issue 1, pp. 117-28, (1996) (PubMed).
: "A sensitive and specific bioassay for the detection of human interleukin-10." in: Journal of immunological methods, Vol. 168, Issue 1, pp. 49-54, (1994) (PubMed).
: "Molecular cloning of rat cytokine synthesis inhibitory factor (IL-10) cDNA and expression in spleen and macrophages." in: Biochemical and biophysical research communications, Vol. 192, Issue 2, pp. 452-8, (1993) (PubMed).
: "Biological properties of interleukin 10." in: Journal of clinical immunology, Vol. 12, Issue 4, pp. 239-47, (1992) (PubMed).
: "Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 4, pp. 1172-6, (1991) (PubMed).
: "Chronic helminth infection reduces basophil responsiveness in an IL-10-dependent manner." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 188, Issue 9, pp. 4188-99, (2012) (PubMed).
: "Recombinant protein yield in rice seed is enhanced by specific suppression of endogenous seed proteins at the same deposit site." in: Plant biotechnology journal, Vol. 10, Issue 9, pp. 1035-45, (2012) (PubMed).
: "NF?B activation and stimulation of chemokine production in normal human macrophages by the gadolinium-based magnetic resonance contrast agent Omniscan: possible role in the pathogenesis of ..." in: Annals of the rheumatic diseases, Vol. 69, Issue 11, pp. 2024-33, (2010) (PubMed).
: "Circulating myeloid dendritic cells of advanced cancer patients result in reduced activation and a biased cytokine profile in invariant NKT cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 11, pp. 7287-93, (2008) (PubMed).
: "Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies." in: Journal of immunological methods, Vol. 188, Issue 1, pp. 117-28, (1996) (PubMed).
: "A sensitive and specific bioassay for the detection of human interleukin-10." in: Journal of immunological methods, Vol. 168, Issue 1, pp. 49-54, (1994) (PubMed).
: "Molecular cloning of rat cytokine synthesis inhibitory factor (IL-10) cDNA and expression in spleen and macrophages." in: Biochemical and biophysical research communications, Vol. 192, Issue 2, pp. 452-8, (1993) (PubMed).
: "Biological properties of interleukin 10." in: Journal of clinical immunology, Vol. 12, Issue 4, pp. 239-47, (1992) (PubMed).
: "Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 4, pp. 1172-6, (1991) (PubMed).
Aliases for IL-10 Proteins
interleukin 10 (IL10) Proteinsinterleukin 10 (Il10) Proteins
CSIF Proteins
GVHDS Proteins
IL-10 Proteins
Il-10 Proteins
IL10A Proteins
IL10X Proteins
TGIF Proteins
Did you look for something else?
- IL-1 beta Proteins
- IKZF5 Proteins
- IKZF4 Proteins
- IKZF3 Proteins
- IKZF2 Proteins
- IKZF1 Proteins
- IKKi/IKKe Proteins
- IKK alpha Proteins
- IKBKG Proteins
- IKBKB Proteins
- IKbIP Proteins
- IKAP/p150 Proteins
- IGSF9 Proteins
- IGSF8 Proteins
- IGSF6 Proteins
- IGSF5 Proteins
- IGSF3 Proteins
- IGSF11 Proteins
- IGSF1 Proteins
- IgM Proteins
- IL-10RA Proteins
- IL-11 Proteins
- IL-13 Proteins
- IL-15 Proteins
- IL-17 Proteins
- IL-17A/F Proteins
- IL-18 Proteins
- IL-19 Proteins
- IL-2 Proteins
- IL-20 Proteins
- IL-21 Proteins
- IL-22 Proteins
- IL-24 Proteins
- IL-25 Proteins
- IL-26 Proteins
- IL-27 Proteins
- IL-3 Proteins
- IL-31 Proteins
- IL-32 alpha Proteins
- IL-33 Proteins
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