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IL-15 Proteins

(Interleukin 15 (IL15))
The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported. [provided by RefSeq, Feb 2011].
IL-15 Protein IL-15 Protein IL-15 Protein (ABIN7274953)

IL15 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by SEC-HPLC

IL-15 Protein (AA 50-162) (His tag) IL-15 Protein (AA 50-162) (His tag) IL-15 Protein (AA 50-162) (His tag) (ABIN6239761)

IL15 Origin: Human Host: Escherichia coli (E. coli) > 97 % AcA, CC Active

IL-15 Protein (AA 49-162) (His-IF2DI Tag) IL-15 Protein (AA 49-162) (His-IF2DI Tag) IL-15 Protein (AA 49-162) (His-IF2DI Tag) (ABIN7123549)

IL15 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA

IL-15 Proteins by Grade

Find IL-15 Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

IL-15 Proteins by Origin

Find IL-15 Proteins for a variety of species such as anti-Human IL-15, anti-Mouse IL-15, anti-Pig IL-15. The species listed below are among those available. Click on a link to go to the corresponding products.

IL-15 Proteins by Source

Here you will find IL-15 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

IL-15 Proteins by Protein Type

Here you can find IL-15 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

IL-15 Proteins by Application

Find IL-15 Proteins validated for a specific application such as SDS, WB, ELISA, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

IL-15 Proteins by Biological Activity

Find IL-15 Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular IL-15 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (5)
Cat. No. ABIN7274953
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (3)
Cat. No. ABIN6239761
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123549
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123550
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307697
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307695
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5570045
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (2)
Cat. No. ABIN6700035
Quantity 2 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN6938879
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (4)
  • (1)
Cat. No. ABIN1047241
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7013412
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (2)
Cat. No. ABIN6386427
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN6731261
Quantity 200 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN6731260
Quantity 200 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7504981
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our IL-15 Proteins

Stone, Chervin, Schreiber, Kranz: "Design and characterization of a protein superagonist of IL-15 fused with IL-15R? and a high-affinity T cell receptor." in: Biotechnology progress, Vol. 28, Issue 6, pp. 1588-97, (2012) (PubMed).

Tagaya, Kurys, Thies, Losi, Azimi, Hanover, Bamford, Waldmann: "Generation of secretable and nonsecretable interleukin 15 isoforms through alternate usage of signal peptides." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 26, pp. 14444-9, (1998) (PubMed).

Krause, Jandrig, Wernicke, Bulfone-Paus, Pohl, Diamantstein: "Genomic structure and chromosomal localization of the human interleukin 15 gene (IL-15)." in: Cytokine, Vol. 8, Issue 9, pp. 667-74, (1997) (PubMed).

Meazza, Verdiani, Biassoni, Coppolecchia, Gaggero, Orengo, Colombo, Azzarone, Ferrini: "Identification of a novel interleukin-15 (IL-15) transcript isoform generated by alternative splicing in human small cell lung cancer cell lines." in: Oncogene, Vol. 12, Issue 10, pp. 2187-92, (1996) (PubMed).

Grabstein, Eisenman, Shanebeck, Rauch, Srinivasan, Fung, Beers, Richardson, Schoenborn, Ahdieh: "Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor." in: Science (New York, N.Y.), Vol. 264, Issue 5161, pp. 965-8, (1994) (PubMed).

Aliases for IL-15 Proteins

interleukin 15 (IL15) Proteins
interleukin 15 (Il15) Proteins
AI503618 Proteins
IL-15 Proteins
IL15 Proteins
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