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MYO9B encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. Additionally we are shipping and many more products for this protein.
Showing 10 out of 29 products:
Human Polyclonal MYO9B Primary Antibody for ELISA, WB - ABIN251552
McMichael, Scherer, Franklin, Lee: The RhoGAP activity of myosin IXB is critical for osteoclast podosome patterning, motility, and resorptive capacity. in PLoS ONE 2014
Show all 2 references for ABIN251552
Human Polyclonal MYO9B Primary Antibody for WB - ABIN374691
Monsuur, de Bakker, Alizadeh, Zhernakova, Bevova, Strengman, Franke, vant Slot, van Belzen, Lavrijsen, Diosdado, Daly, Mulder, Mearin, Meijer, Meijer, van Oort, Wapenaar, Koeleman, Wijmenga: Myosin IXB variant increases the risk of celiac disease and points toward a primary intestinal barrier defect. in Nature genetics 2005
Human Polyclonal MYO9B Primary Antibody for ELISA, WB - ABIN1451373
Grewal, Jones, Maconochie, Lemmers, Frants, Hewitt: Cloning of the murine unconventional myosin gene Myo9b and identification of alternative splicing. in Gene 2000
Data show that myo9b is localized in actin-rich ellipsoids of fish cones.
this meta-analysis shows that MYO9B genetic polymorphism is associated with Crohn's disease and ulcerative colitis
newly defined SLIT/ROBO/Myo9b/RhoA (show RHOA Antibodies) signaling pathway that restricts lung cancer progression and metastasis.
Our data suggest a link between MYO9B variants to an increased intestinal permeability in Crohn's disease patients.
Results does not support the association of MYO9B with schizophrenia in Chinese population.
MYO9B SNPs may influence the sub-phenotypic expression of Crohn's disease but did not find an association between these MYO9B polymorphisms and intestinal permeability in IBD.
Variants in MYO9B may be involved in acute pancreatitis
genetic variation MYO9B gene is associated with celiac disease as a protective or a risk factor
The homozygous G/G group of theMyo9B polymorphism was associated with an increased risk for Barrett's esophagus and esophageal adenocarcinoms (EAC (show CYLD Antibodies)) development. Also the heterozygous A/G genotype was associated with an increased risk for EAC (show CYLD Antibodies) development.
critical roles for Myo9b during epithelial wound healing and maintenance of tight junction integrity-key functions that may be altered in patients with Myo9b-linked inflammatory bowel disease.
we performed genetic analysis of the MYO9B gene and the IL-2 (show IL2 Antibodies)/IL-21 (show IL17C Antibodies) locus by genotyping SNPs that have been previously associated with coeliac disease or schizophrenia found no evidence for association with these two loci.
This study shows that Myo9b in hematopoietic cells impacts on the induction and progression of EAE. Specifically, Myo9b regulates the onset of EAE symptoms, which correlates with immune cell proliferation and infiltration into the CNS.
we have identified Myo9b as a key regulator of spatiotemporal Rho activity in DCs with cofilin (show CFL1 Antibodies) as a target protein of major importance for the regulation of DC migration and T cell stimulatory capacity.
Data identify the "motorized Rho inhibitor" Myo9b as a key molecular component required for spatially coordinated cell shape changes and motility.
Myo9b functions as a motorized molecule in regions of actin polymerization and Myo9b head sequences are important for in vivo motor properties.
This gene encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. The protein represents an unconventional myosin\; it should not be confused with the conventional non-muscle myosin-9 (MYH9). The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain. The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end. The protein also has rho-GTPase activity. Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene.
, Unconventional myosin from rat 3
, myr 5
, unconventional myosin-9b
, unconventional myosin-IXb
, unconventional myosin IXb