MYO9B antibody (AA 280-360)

Catalog No. ABIN7222626

The Rabbit Polyclonal anti-MYO9B antibody (ABIN7222626) specifically detects MYO9B in WB, ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for MYO9B antibody (AA 280-360) (ABIN7222626)

Target: MYO9B (Myosin IXB (MYO9B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYO9B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-MYO9B Antibody

Binding Specificity: AA 280-360

Purpose: Rabbit Anti-Myosin IXb Polyclonal Antibody

Specificity: Myosin IXb Polyclonal Antibody detects endogenous levels of Myosin IXb protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human Myosin IXb at AA range: 280-360

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MYO9B

Target: MYO9B (Myosin IXB (MYO9B))

Alternative Name: Myosin IXb

Background: MYO9B, MYR5, Unconventional myosin-IXb, Unconventional myosin-9bMYO9B encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. The protein represents an unconventional myosin, it should not be confused with the conventional non-muscle myosin-9 (MYH9). The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain. The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end. The protein also has rho-GTPase activity. Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility. Multiple transcript variants encoding different isoforms have been found for MYO9B.

Molecular Weight: 250kD

Gene ID: 4650

UniProt: Q13459