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anti-Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) Antibodies

The protein encoded by MARCKS is a substrate for protein kinase C. Additionally we are shipping MARCKS Kits (17) and MARCKS Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MARCKS 17118 P26645
MARCKS 25603  
MARCKS 4082 P29966
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Top anti-MARCKS Antibodies at antibodies-online.com

Showing 10 out of 233 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from K562 cells treated with EGF 200ng/ml 30', using MARCKS (Phospho-Ser158) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from Jurkat cells, using MARCKS (Ab-158) Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of A549 cells, using MARCKS (Ab-158) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of hMARCKS-K254 (ABIN389097) in Hela cell line lysates (35 µg/lane). MARCKS (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated WB MARCKS monoclonal antibody (M04), clone 2H4. Western Blot analysis of MARCKS expression in Raw 264.7. Detection limit for recombinant GST tagged MARCKS is approximately 0.1 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to MARCKS on HeLa cell (antibody concentration 10 µg/mL). MARCKS monoclonal antibody (M06), clone 2C2. Western Blot analysis of MARCKS expression in Raw 264.7. (OMIN,80 kDa,http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=177061 50 μg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB 0.1 mL Log in to see 6 to 8 Days
$308.00
Details
Human Rabbit Un-conjugated IF, WB 0.1 mL Log in to see 6 to 8 Days
$308.00
Details
Human Rabbit Un-conjugated IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$357.50
Details
Human Rabbit Un-conjugated IF 0.1 mL Log in to see 6 to 8 Days
$357.50
Details

MARCKS Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-MARCKS Antibodies

  1. Human Polyclonal MARCKS Primary Antibody for EIA, WB - ABIN357762 : Rauch, Ferguson, Prestwich, Cafiso: Myristoylated alanine-rich C kinase substrate (MARCKS) sequesters spin-labeled phosphatidylinositol 4,5-bisphosphate in lipid bilayers. in The Journal of biological chemistry 2002 (PubMed)
    Show all 5 references for ABIN357762

  2. Human Monoclonal MARCKS Primary Antibody for IF, WB - ABIN2838585 : Lin, Fang, Park, Crews, Adler: MARCKS and related chaperones bind to unconventional myosin V isoforms in airway epithelial cells. in American journal of respiratory cell and molecular biology 2010 (PubMed)
    Show all 5 references for ABIN2838585

  3. Human Polyclonal MARCKS Primary Antibody for WB - ABIN389097 : Aderem: The MARCKS family of protein kinase-C substrates. in Biochemical Society transactions 1996 (PubMed)
    Show all 5 references for ABIN389097

  4. Human Monoclonal MARCKS Primary Antibody for WB - ABIN393637 : Techasen, Loilome, Namwat, Takahashi, Sugihara, Puapairoj, Miwa, Saya, Yongvanit: Myristoylated alanine-rich C kinase substrate phosphorylation promotes cholangiocarcinoma cell migration and metastasis via the protein kinase C-dependent pathway. in Cancer science 2010 (PubMed)
    Show all 5 references for ABIN393637

  5. Human Polyclonal MARCKS Primary Antibody for IHC (p), WB - ABIN401558 : Ramsden: MARCKS: a case of molecular exaptation? in The international journal of biochemistry & cell biology 2001 (PubMed)
    Show all 4 references for ABIN401558

  6. Human Polyclonal MARCKS Primary Antibody for IF - ABIN401578 : Pariser, Herradon, Ezquerra, Perez-Pinera, Deuel: Pleiotrophin regulates serine phosphorylation and the cellular distribution of beta-adducin through activation of protein kinase C. in Proceedings of the National Academy of Sciences of the United States of America 2005 (PubMed)
    Show all 2 references for ABIN401578

  7. Human Polyclonal MARCKS Primary Antibody for IF, WB - ABIN197560 : Nagumo, Ikenoya, Sakurada, Furuya, Ikuhara, Hiraoka, Sasaki: Rho-associated kinase phosphorylates MARCKS in human neuronal cells. in Biochemical and biophysical research communications 2001 (PubMed)
    Show all 2 references for ABIN197560

  8. Human Polyclonal MARCKS Primary Antibody for IF, ELISA - ABIN1532929 : Sakai, Hirai, Kudoh, Minoshima, Shimizu: Molecular cloning and chromosomal mapping of a cDNA encoding human 80K-L protein: major substrate for protein kinase C. in Genomics 1992 (PubMed)
    Show all 2 references for ABIN1532929

  9. Human Polyclonal MARCKS Primary Antibody for ELISA, WB - ABIN1531898 : Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: The DNA sequence and analysis of human chromosome 6. ... in Nature 2003 (PubMed)

More Antibodies against MARCKS Interaction Partners

Xenopus laevis Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) interaction partners

  1. The results indicated MARCKS may be the missing link in the regulation of the function (i.e., sodium transport) of epithelial sodium channels by anionic phospholipids.

Mouse (Murine) Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) interaction partners

  1. Conditional deletion of MARCKS in ECs induces intracellular accumulation of mucins, elevated oxidative stress, and lipid droplet buildup.

  2. MARCKS acts as a "molecular switch," binding to and regulating PIP2 signaling to regulate processes like proplatelet extension (microtubule-driven) vs proplatelet branching (Arp2/3 and actin polymerization-driven).

  3. MARCKS knockdown arrested VSMC cell cycle by decreasing KIS (show UHMK1 Antibodies) expression. Decreased KIS (show UHMK1 Antibodies) expression resulted in nuclear trapping of p27kip1 (show CDKN1B Antibodies) in VSMCs.

  4. MARCKS regulates the expression of proinflammatory cytokines in macrophages through activation of p38 (show CRK Antibodies)/JNK (show MAPK8 Antibodies) MAPK (show MAPK1 Antibodies) and NF-kappaB (show NFKB1 Antibodies).

  5. Targeting phospho-MARCKS overcomes drug-resistance and induces antitumor activity in preclinical models of multiple myeloma.

  6. Grin 1 (show GPRIN1 Antibodies) is identified as a novel Cdk5 (show CDK5 Antibodies) substrate and MARCKS is confirmed as a Cdk5 (show CDK5 Antibodies) substrate.

  7. MARCKS appears to be a nonessential regulatory protein in mast cell exocytosis but exerts a negative modulation.

  8. MARCKS overexpression in the hippocampus of old mice leads to long-term potentiation and improved memory.

  9. an important functional role for the interaction between MARCKS and PSA (show NPEPPS Antibodies) in the developing and adult nervous system.

  10. cathepsin K (show CTSK Antibodies) exocytosis is controlled by PKCdelta (show PKCd Antibodies) through modulation of the actin bundling protein myristoylated alanine-rich C-kinase substrate.

Zebrafish Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) interaction partners

  1. Marcksb is required for proper gastrulation movements of zebrafish.

Human Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) interaction partners

  1. Knockdown of MARCKS in HepG2 cells reduced cell migration and invasion, but not cell proliferation.

  2. MARCKS upregulation increases vascular smooth muscle cell motility by activation of Rac1 and Cdc42 (show CDC42 Antibodies), promoting neointima formation.

  3. A novel role for MARCKS in regulating nuclear functions such as gene expression.

  4. MARCKS knockdown arrested VSMC cell cycle by decreasing KIS (show UHMK1 Antibodies) expression. Decreased KIS (show UHMK1 Antibodies) expression resulted in nuclear trapping of p27kip1 (show CDKN1B Antibodies) in VSMCs.

  5. unresponsiveness of breast cancer to paclitaxel treatment is, at least in part, mediated by phospho-MARCKS

  6. MARCKS and PPP1R9A (show PPP1R9A Antibodies) might contribute to spine loss in schizophrenia and bipolar disorder through their interactions.

  7. isotype delta-PKC (show PRRT2 Antibodies) is responsible for myristoylated alanine-rich C-kinase substrate (MARCKS) phosphorylation in human neutrophils following f-Met-Leu-Phe stimulation and MARCKS phosphorylation is essential for neutrophil migration and adhesion.

  8. A key role of the effector domain of MARCKS in terms of cellular response, particularly to radiation: the importance of MARCKS phosphorylation status for its subcellular localization in lung cancer.

  9. MARCKS overexpression was observed in several drug-resistant human myeloma cell lines and in drug-resistant primary multiple myeloma samples.

  10. Finding that MARCKS acts as a mediator of apoptosis in microsatellite stable colorectal cancer cells adds a novel tumor-suppressing function to the established roles of MARCKS in cell motility and proliferation.

Cow (Bovine) Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) interaction partners

  1. MARCKS protein mediates hydrogen peroxide regulation of endothelial permeability.

  2. a critical role for H(2)O(2) in angiotensin-II signaling to the endothelial cytoskeleton in a novel pathway that is critically dependent on MARCKS, Rac1, and c-Abl.

  3. These findings demonstrate a critical role for MARCKS-phosphatidylinositol-4,5-diphosphate signaling in regulating dendrite development.

  4. Protein kinase C (show PKC Antibodies) mediated inhibition of endothelial L-arginine (show GATM Antibodies) transport is mediated by MARCKS protein

MARCKS Antigen Profile

Protein Summary

The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.

Gene names and symbols associated with MARCKS

  • myristoylated alanine-rich protein kinase C substrate (marcks) antibody
  • myristoylated alanine-rich protein kinase C substrate (MARCKS) antibody
  • myristoylated alanine-rich protein kinase C substrate (LOC100345174) antibody
  • methyl binding domain (mbd106) antibody
  • myristoylated alanine rich protein kinase C substrate (marcks) antibody
  • myristoylated alanine rich protein kinase C substrate (Marcks) antibody
  • myristoylated alanine rich protein kinase C substrate b (marcksb) antibody
  • 80K-L antibody
  • KINC antibody
  • MACS antibody
  • MARCKS antibody
  • MGC89127 antibody
  • PKCSL antibody
  • PRKCSL antibody
  • wu:fb55c06 antibody
  • wu:fb92d04 antibody
  • wu:fc19b04 antibody
  • wu:fc44a10 antibody
  • zgc:110235 antibody

Protein level used designations for MARCKS

myristoylated alanine-rich protein kinase C substrate , methyl binding domain , Zmmbd2 , PCO124731 , PCO124731_ov , myristoylated alanine-rich C-kinase substrate , Myristoylated alanine-rich protein kinase C substrate , protein kinase C substrate 80 kDa protein , myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L) , phosphomyristin , protein kinase C substrate, 80 kDa protein, light chain , myristoylated alanine-rich C kinase substrate (MARCKS) , ACAMP-81

GENE ID SPECIES
448317 Xenopus (Silurana) tropicalis
694077 Macaca mulatta
742020 Pan troglodytes
100345174 Oryctolagus cuniculus
542069 Zea mays
379767 Xenopus laevis
17118 Mus musculus
25603 Rattus norvegicus
323201 Danio rerio
4082 Homo sapiens
396473 Gallus gallus
613548 Bos taurus
612436 Canis lupus familiaris
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