MARCKS antibody (AA 241-271)
Quick Overview for MARCKS antibody (AA 241-271) (ABIN3031923)
Target
See all MARCKS AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 241-271
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Purpose
- MARCKS Antibody
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Purification
- Purified
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Immunogen
- A portion of amino acids 241-271 from the human protein was used as the immunogen for this MARCKS antibody.
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Isotype
- Ig Fraction
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Application Notes
- Titration of the MARCKS antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the MARCKS antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- MARCKS (Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS))
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Alternative Name
- MARCKS
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Background
- MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.
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UniProt
- P29966
Target
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