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anti-Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) Antibodies

NFE2L2 encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. Additionally we are shipping NRF2 Kits (34) and NRF2 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NFE2L2 4780 Q16236
NFE2L2 18024 Q60795
NFE2L2 83619 O54968
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Top anti-NRF2 Antibodies at antibodies-online.com

Showing 10 out of 167 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of NFE2L2 (arrow) using NFE2L2 Antibody . 293 ce... 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-NFE2L2 Antibody Titration: 1.25ug/mlELISA Titer: 1:1... 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of anti-NFE2L2 (N-term) in Ramos cell line lysat... Western blot analysis of Nrf2(Nfe2l2)(arrow) using rabbit polyclonal N... 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human endometrial cancer labeled ... Formalin-fixed and paraffin embedded mouse myocardium labeled with (AB... 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IHC (fro), IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat tongue tissue labeled with An... Formalin-fixed and paraffin embedded rat kidney tissue labeled with An... 100 μL Log in to see 3 to 7 Days
$291.50
Details
Human Mouse Un-conjugated IHC, ELISA, WB 0.1 mg Log in to see 3 to 4 Days
$430.10
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 0.1 mg Log in to see 2 to 6 Days
$359.70
Details
Human Rabbit Un-conjugated WB Western blot analysis of anti-NFE2L2 Antibody (N-term) (ABIN391424) in... Western blot analysis of Nrf2(Nfe2l2)(arrow) using rabbit polyclonal N... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p) 7 mL Log in to see 2 to 3 Days
$226.00
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB Western blot analysis of extracts from HuvEc cells, using Nrf2 Antibod... Immunohistochemistry analysis of paraffin-embedded human lung carcinom... 100 μg Log in to see 2 to 3 Days
$275.00
Details

NFE2L2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
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Top referenced anti-NRF2 Antibodies

  1. Human Polyclonal NRF2 Primary Antibody for IF (p), IHC (p) - ABIN737271 : Lee, Hsu, Chang, Kuo, Hsu, Pan: Ankaflavin: a natural novel PPAR? agonist upregulates Nrf2 to attenuate methylglyoxal-induced diabetes in vivo. in Free radical biology & medicine 2012 (PubMed)
    Show all 10 references for ABIN737271

  2. Human Polyclonal NRF2 Primary Antibody for IHC (fro), IF (p) - ABIN676673 : Lee, Hsu, Hsu, Pan: Dimerumic acid attenuates receptor for advanced glycation endproducts signal to inhibit inflammation and diabetes mediated by Nrf2 activation and promotes methylglyoxal metabolism into d-lactic acid. in Free radical biology & medicine 2013 (PubMed)
    Show all 10 references for ABIN676673

  3. Human Polyclonal NRF2 Primary Antibody for EIA, WB - ABIN359516 : Li, Jang, Na, Cha, Surh: Carbon monoxide produced by heme oxygenase-1 in response to nitrosative stress induces expression of glutamate-cysteine ligase in PC12 cells via activation of phosphatidylinositol 3-kinase and Nrf2 signaling. in The Journal of biological chemistry 2007 (PubMed)
    Show all 2 references for ABIN359516

  4. Human Polyclonal NRF2 Primary Antibody for IHC, ELISA - ABIN1584873 : Bagul, Middela, Matapally, Padiya, Bastia, Madhusudana, Reddy, Chakravarty, Banerjee: Attenuation of insulin resistance, metabolic syndrome and hepatic oxidative stress by resveratrol in fructose-fed rats. in Pharmacological research : the official journal of the Italian Pharmacological Society 2012 (PubMed)
    Show all 2 references for ABIN1584873

  5. Human Polyclonal NRF2 Primary Antibody for EIA, WB - ABIN359515 : Zhao, Sun, Zhang, Strong, Dash, Kan, Grotta, Aronowski: Transcription factor Nrf2 protects the brain from damage produced by intracerebral hemorrhage. in Stroke; a journal of cerebral circulation 2007 (PubMed)
    Show all 2 references for ABIN359515

  6. Human Monoclonal NRF2 Primary Antibody for IHC, ELISA - ABIN1724931 : Sandford, Malhotra, Boezen, Siedlinski, Postma, Wong, Akhabir, He, Connett, Anthonisen, Paré, Biswal: NFE2L2 pathway polymorphisms and lung function decline in chronic obstructive pulmonary disease. in Physiological genomics 2012 (PubMed)

  7. Chicken Polyclonal NRF2 Primary Antibody for WB - ABIN2780749 : Padmanabhan, Tong, Ohta, Nakamura, Scharlock, Ohtsuji, Kang, Kobayashi, Yokoyama, Yamamoto: Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer. in Molecular cell 2006 (PubMed)

More Antibodies against NRF2 Interaction Partners

Zebrafish Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) interaction partners

  1. Bach1 (show BACH1 Antibodies) regulates the liver specificity and transience of the Nrf2a-dependent induction of hmox1a and that heme mediates this regulation through Bach1 (show BACH1 Antibodies) inhibition based on its level in each tissue.

  2. The Bach1b-MafK heterodimer represses the zymogen promoters, whereas the Nrf2a-MafK heterodimer activates them.

  3. The expression of nrf (show NRF1 Antibodies) genes varies temporally throughout development and nrf (show NRF1 Antibodies) genes are induced following a pro-oxidant exposure and are potentially cross-regulated by gene family members Nrf2a and Nrf2b (show GABPb Antibodies).

  4. oxidative stress is an important mechanism of Cd-mediated injury in the zebrafish olfactory system; the Nrf2 pathway plays a protective role against cellular oxidative damage and is important in maintaining zebrafish olfactory function.

  5. results revealed that nrf2 mutant zebrafish are viable and fertile but show an increased susceptibility to oxidative stress and electrophiles

  6. compared the tissue-specific expression of several Nrf2 target genes in zebrafish larvae; Tissue-restricted induction was observed in the nose, gill, and/or liver for seven genes in response to Nrf2-activating compounds

  7. Nrf2 is protective against PFOS-induced oxidative stress in zebrafish larvae.

  8. mutation of either residual cysteine residue in Keap1a (show KEAP1 Antibodies) and Keap1b disrupted the ability of Keap1 (show KEAP1 Antibodies) to repress Nrf2, indicating that the presence of either Cys (show DNAJC5 Antibodies)-273 or Cys (show DNAJC5 Antibodies)-288 is sufficient for fish Keap1 (show KEAP1 Antibodies) molecules to fully function

  9. study reports that the Keap1 (show KEAP1 Antibodies)-Nrf2 system comprises discrete sensor sites, including the Keap1 (show KEAP1 Antibodies) cysteines Cys (show DNAJC5 Antibodies)-151 and Cys (show DNAJC5 Antibodies)-273, for a variety of Nrf2-activating compounds

  10. findings demonstrate that antioxidant responses are a component of polycyclic aromatic hydrocarbon (PAH)synergistic developmental toxicity and that NRF2 is protective against prooxidant and PAH challenges during development

Cow (Bovine) Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) interaction partners

  1. These findings suggest that bronchiolar epithelial cells and macrophages up-regulate Nrf2 expression early in the course of infection, which results in increased expression of HO-1 (show HMOX1 Antibodies) within these cells.

  2. the survival and developmental competence of embryos cultured under oxidative stress are associated with activity of the NRF2-mediated oxidative stress response pathway during bovine pre-implantation embryo development.

  3. investigation of molecular mechanisms of microvascular complications in diabetes/hyperglycemia: Nrf2 is involved in regulation of HO-1 (show HMOX1 Antibodies) gene expression in aortic endothelial cells by advanced glycation end products

Pig (Porcine) Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) interaction partners

  1. The effects of ochratoxin A on the nuclear translocation and transactivation of the transcription factor Nrf2 as well as mRNA levels of Nrf2 target genes are reported.

Human Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) interaction partners

  1. Overexpression of Nrf2 (show GABPA Antibodies) inhibited the PBK/TOPK (show PBK Antibodies) KD-induced decrease in cdc2 (show CDK1 Antibodies) and cyclin B expression and cell cycle arrest, and blocked ROS (show ROS1 Antibodies) production and apoptosis.

  2. This shows for the first time that Nrf2 (show GABPA Antibodies) action can potently block HIV infection

  3. Nrf2 (show GABPA Antibodies) and Nrf2 (show GABPA Antibodies)-related genes were aberrantly expressed in cirrhotic livers and hepatocellular carcinoma.

  4. Findings demonstrated that miR (show MLXIP Antibodies)-153 overexpression decreased radioresistance and stemness of GSCs through targeting Nrf-2 (show GABPA Antibodies)/GPx1 (show GPX1 Antibodies)/ROS (show ROS1 Antibodies) pathway.

  5. Our study points to the relevance of LAPTM4B expression to NSCLC pathogenesis as well as to the probable role of LAPTM4B/NRF2 (show GABPA Antibodies) signaling in promoting lung cancer cell survival.

  6. Na2S therapy enhances proteasomal activity and function during the development of heart failure in an Nrf2 (show GABPA Antibodies)-dependent manner and that this enhancement leads to attenuation in cardiac dysfunction.

  7. Keap1 (show KEAP1 Antibodies) functions as a suppressor of tumor metastasis by targeting the Nrf2 (show GABPA Antibodies)/S100P (show S100P Antibodies) pathway in NSCLC cells.

  8. miR (show MLXIP Antibodies)-126-3p and -5p were identified as NRF2 (show GABPA Antibodies) target microRNAs, and a rSNP residing on NRF2 (show GABPA Antibodies) target gene (Ferritin (show FTL Antibodies), light polypeptide, FTL (show FTL Antibodies)) promoter was experimentally verified to decrease NRF2 (show GABPA Antibodies) binding and result in decreased transcriptional activity

  9. effect of Tat (show TAT Antibodies) on Nrf2 (show GABPA Antibodies) activation in human neuroblastoma (show ARHGEF16 Antibodies) cells and the role of NMDA receptor and spermine oxidase (show SMOX Antibodies) on Tat (show TAT Antibodies)-induced nuclear factor erythroid 2-related factor 2 (Nrf2) activation

  10. Nrf2 (show GABPA Antibodies) expression is positively correlated with invasive gastric cancer, suggesting its utility as a predictive index for unfavorable prognosis

Mouse (Murine) Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) interaction partners

  1. Irradiation inhibits osteoblast differentiation and mineralization of MC3T3-E1 cells through the oxidative stress-mediated activation of Nrf2/HO-1 (show HMOX1 Antibodies) pathway.

  2. low 4-Hydroxy-2-nonenal (HNE (show ELANE Antibodies)) doses activate Nrf2 in cardiomyocytes and provide the first evidence of Nrf2 binding to the Ucp3 (show UCP3 Antibodies) promoter in response to HNE (show ELANE Antibodies), leading to increased protein expression

  3. Mechanistic interpretation for this GSTP (show GSTP1 Antibodies)-dependent effect may include a direct and redox-sensitive interaction of GSTP (show GSTP1 Antibodies) with Nrf2 protein

  4. Results demonstrate Nrf2 regulates the generation, survival, and suppressive potency of myeloid-derived suppressor cells (MDSC), and that a feedback homeostatic mechanism maintains a steady-state level of circulating MDSC in tumor-bearing individuals.

  5. H2 suppresses ROS (show ROS1 Antibodies) accumulation by upregulating Nrf2 signaling, which may contribute to its inhibitory effect on macrophage apoptosis

  6. Cacul1 regulates the antioxidant response by stabilizing Nrf2.

  7. results show that the anti-oxidative and anti-inflammatory effects of digitoflavone are mediated by Nrf2 activation and that digitoflavone can be used therapeutically to improve metabolic disorders and relieve renal damage induced by diabetes.

  8. We conclude that melatonin, via modulation of PKC (show PKC Antibodies) and Ca(2 (show CA2 Antibodies)+) signaling, could potentially stimulate the Nrf2-mediated antioxidant response in mouse pancreatic acinar cells.

  9. Lutein attenuates neuroinflammation in lipopolysaccharide activated BV-2 microglia partly through inhibiting p38 (show CRK Antibodies)-, JNK (show MAPK8 Antibodies)-, and Akt (show AKT1 Antibodies)-stimulated NF-kappaB (show NFKB1 Antibodies) activation and promoting ERK (show EPHB2 Antibodies)-induced Nrf2 activation.

  10. Chronic hyperglycemia-associated oxidative stress inhibits nuclear translocation of Nrf2 and impairs activation of antioxidant genes, thus contributing to ROS (show ROS1 Antibodies) accumulation.

NRF2 (NFE2L2) Antigen Profile

Protein Summary

This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters\; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with NFE2L2

  • nuclear factor (erythroid-derived 2)-like 2a (nfe2l2a) antibody
  • nuclear factor (erythroid-derived 2)-like 2 (nfe2l2) antibody
  • nuclear factor (erythroid-derived 2)-like 2 (NFE2L2) antibody
  • nuclear factor, erythroid 2-like 2 (NFE2L2) antibody
  • nuclear factor, erythroid derived 2, like 2 (Nfe2l2) antibody
  • AI194320 antibody
  • NF-E2R2 antibody
  • nfe2l2 antibody
  • NRF2 antibody
  • wu:fc15g09 antibody
  • wu:fj67e03 antibody

Protein level used designations for NFE2L2

Nrf2a , nuclear factor (erythroid-derived 2)-like 2 , nuclear factor erythroid 2-related factor 2 , ECH , NF-E2-related factor 2 , NFE2-related factor 2 , nuclear factor, erythroid derived 2, like 2 , HEBP1 , nuclear factor erythroid-derived 2-like 2 , nrf2 , nuclear factor erythroid 2-like 2

GENE ID SPECIES
360149 Danio rerio
444736 Xenopus laevis
396014 Gallus gallus
478813 Canis lupus familiaris
497024 Bos taurus
100516343 Sus scrofa
4780 Homo sapiens
18024 Mus musculus
83619 Rattus norvegicus
Selected quality suppliers for anti-NRF2 (NFE2L2) Antibodies
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