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OLR1 encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. Additionally we are shipping OLR1 Kits (57) and OLR1 Proteins (25) and many more products for this protein.
Showing 10 out of 208 products:
Human Polyclonal OLR1 Primary Antibody for IF (p), IHC (p) - ABIN676988
Wu, Tang, Jiang, Li, Jiang, Liu: PCSK9 siRNA inhibits HUVEC apoptosis induced by ox-LDL via Bcl/Bax-caspase9-caspase3 pathway. in Molecular and cellular biochemistry 2011
Show all 5 references for ABIN676988
Human Monoclonal OLR1 Primary Antibody for ELISA - ABIN393293
Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010
Show all 5 references for ABIN393293
Human Monoclonal OLR1 Primary Antibody for Func, IF - ABIN1108522
NOYES, DOMM, WILLSLC: Regulation of erythropoiesis. I. Erythropoietin assay as a clinical tool. in Blood 1970
Show all 4 references for ABIN1108522
Human Monoclonal OLR1 Primary Antibody for Func, IF - ABIN1108520
Delneste, Magistrelli, Gauchat, Haeuw, Aubry, Nakamura, Kawakami-Honda, Goetsch, Sawamura, Bonnefoy, Jeannin: Involvement of LOX-1 in dendritic cell-mediated antigen cross-presentation. in Immunity 2002
Show all 4 references for ABIN1108520
Mouse (Murine) Monoclonal OLR1 Primary Antibody for FACS - ABIN4897693
Biedroń, Konopiński, Marcinkiewicz, Józefowski: Oxidation by neutrophils-derived HOCl increases immunogenicity of proteins by converting them into ligands of several endocytic receptors involved in antigen uptake by dendritic cells and macrophages. in PLoS ONE 2015
Show all 2 references for ABIN4897693
Human Polyclonal OLR1 Primary Antibody for IHC (p), WB - ABIN652795
Predazzi, Martínez-Labarga, Vecchione, Mango, Ciccacci, Amati, Ottoni, Crawford, Rickards, Romeo, Novelli: Population differences in allele frequencies at the OLR1 locus may suggest geographic disparities in cardiovascular risk events. in Annals of human biology 2010
Human Polyclonal OLR1 Primary Antibody for ELISA, WB - ABIN4331396
Shi, Cosentino, Camici, Akhmedov, Vanhoutte, Tanner, Lüscher: Oxidized low-density lipoprotein activates p66Shc via lectin-like oxidized low-density lipoprotein receptor-1, protein kinase C-beta, and c-Jun N-terminal kinase kinase in human endothelial cells. in Arteriosclerosis, thrombosis, and vascular biology 2011
ox-LDL and LOX-1 increase due to subarachnoid hemorrhage and they may play a role in the pathogenesis of vasospasm.
LOX (show LOX Antibodies) and LOXL2 (show LOXL2 Antibodies) play an important role in wound healing after glaucoma filtration surgery. Targeting LOXL2 (show LOXL2 Antibodies) with an inhibitory monoclonal antibody (GS-607601) had a broader efficacy than targeting LOX (show LOX Antibodies), reducing angiogenesis and inflammation, and fibrosis.
Angiotensin (1-7) inhibited LOX-1 expression and diminished Ang II (show AGT Antibodies)-mediated inflammation in endothelial cells
Elevated LOX-1 expression and inflammatory responses are induced in hypercholesterolemic rabbits by Chlamydia pneumoniae GroEL1 heat shock protein.
Early treatment with fluvastatin had a crucial endothelial protective effect by down-regulating LOX-1 expression level in atherosclerotic arteries in early atherosclerosis.
LOX-1 expression appears to be closely associated with tissue factor (show F3 Antibodies) expression, apoptotic events and morphological vulnerability in atherosclerotic lesions
OLR1 rs1050286 SNP may contribute to modify OLR1 susceptibility to acute myocardial infarction and coronary artery diseases.
Serum sLOX-1 level was significantly lower in the restless legs syndrome patient group compared to controls.
The mechanistic link between miR (show MLXIP Antibodies)-590-5p and LOX-1:miR (show MLXIP Antibodies)-590-5p downregulation led to LOX-1 upregulation in endothelial cells.
the current meta-analysis highlighted that variant allele of OLR1 rs11053646 G > C and PCSK9 (show PCSK9 Antibodies) rs505151 A > G may contribute to the susceptibility risk of ischemic stroke.
Silencing of LOX-1 gene expression abolished ox-LDL induced effects in cell viability, reactive oxygen species generation and gene expression.
both the 501>C single nucleotide polymorphisms in the LOX1 gene and the serum LOX1 level may be used to predict the development of left ventricular hypertrophy among essential hypertension patients.
rapamycin reduces mTOR (show FRAP1 Antibodies) phosphorylation and subsequently inhibit NF-kappaB (show NFKB1 Antibodies) activation and suppresses LOX-1, resulting in a reduction in ox-LDL uptake in HUVECs
for our Turkish sample group, LOX-1 30UTR188C/T and K167N polymorphisms may not be involved in susceptibility to GDM [gestational diabetes mellitus ]
Cholesterol depletion triggers the release of LOX-1 in exosomes as a full-length transmembrane isoform and as a truncated ectodomain soluble fragment.
Interaction between Lox-1, C-reactive protein (show CRP Antibodies) and oxidized LDL play role in the pathogenesis of atherosclerosis.
LOX-1/ox-LDL system plays a pivotal role in the pathogenesis of instability-induced osteoarthritis through endochondral ossification.
that ox-LDL receptor-1 and PCSK9 (show PCSK9 Antibodies) positively influence each other's expression, especially during an inflammatory reaction
LOX1 is implicated in OxLDLinduced oxidative stress of macrophages in atherosclerosis, which in part, involves the regulation of NADPH (show FDXR Antibodies) oxidases.
LOX-1 is, at least in part, responsible for the inhibitory effect of ox-LDL on macrophage migration and this process involves calpain-1 (show CAPN1 Antibodies) and -2.
mice with LOX-1 deletion given similar infusion of angiotensin II showed much less rise in blood pressure, and less expression of NADPH oxidase (show NOX1 Antibodies), activation of P38 MAPK (show MAPK14 Antibodies) and nuclear factor-kappaB, autophagy-related proteins and TLR4 (show TLR4 Antibodies) than wild-type mice.
LOX-1 plays an important role in ischemia-induced angiogenesis by 1) Nox2 (show CYBB Antibodies)-ROS (show ROS1 Antibodies)-NF-kappaB (show NFKB1 Antibodies) activation, 2) upregulated expression of adhesion molecules: VCAM-1 (show VCAM1 Antibodies) and LOX-1 and 3) promoting macrophage infiltration.
Our findings indicate the novel involvement of LOX-1 in physiological bone homeostasis and inflammatory bone diseases.
LOX-1 activation by oxLDL is an important event that enhances tumor angiogenesis
our results indicate that LPS (show TLR4 Antibodies) up-regulates LOX-1, at least in part through activation of the Erk1/2 (show MAPK1/3 Antibodies) signaling pathway,thus highlighting a critical role of TLR4 (show TLR4 Antibodies)-mediated aberrant LOX-1 signaling in the pathogenesis of atherosclerosis
data indicated that olmesartan may attenuate the impairment of endothelial cell via down-regulation of the increased LOX-1 expression induced by ox-LDL.
Overexpression of LOX-1 leads to the attenuation of protective autophagy response in aortic endothelial cells.
These results imply that the 3' UTR (show UTS2R Antibodies) SNP of the OLR1 gene is a strong candidate marker for selection in cattle breeding programs.
Our data indicate that blocking the LOX-1 receptor signal pathway might be a promising way to improve steroid hormone concentrations in metabolically highly active female mammals
In the present study, we show that inhibition of LOX-1 leads to a rearrangement of ceramide from the basal membrane toward the Golgi apparatus
The downregulation of eNOS (show NOS3 Antibodies) by ox-low-density lipoprotein, as driven by LOX-1-mediated endoplasmic stress, is associated with the PI3K-Akt (show AKT1 Antibodies)-eNOS (show NOS3 Antibodies) signaling pathway.
3'-UTR (show UTS2R Antibodies) SNP assoicated with milk composition traits and somatic cell score
Oxidized low-density lipoprotein receptor (show LDLR Antibodies) (OLR1) single nucleotide polymorphism haplotype is associated with milk fat yield and fat percentage
synergistic effects of cyclic tensile stretch load and ox-LDL on cell viability and proteoglycan (show Vcan Antibodies) synthesis in chondrocytes, which may be mediated through enhanced expression of LOX-1
Upregulates VEGF (show VEGFA Antibodies) expression in articular cartilage, at least in part, through activation of PPAR-gamma (show PPARG Antibodies).
Mediation of electronegative low-density lipoprotein signaling by LOX-1: a possible mechanism of endothelial apoptosis.
This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.
oxidised low density lipoprotein (lectin-like) receptor 1
, oxidized low density lipoprotein (lectin-like) receptor 1
, lectin-like oxLDL receptor 1
, lectin-like oxidized LDL receptor 1
, lectin-type oxidized LDL receptor 1
, ox-LDL receptor 1
, oxidized low-density lipoprotein receptor 1
, C-type lectin domain family 8 member A
, ox LDL receptor 1
, oxidized low-density lipoprotein receptor 1, soluble form
, scavenger receptor class E, member 1
, Lectin-like oxidized low-density lipoprotein receptor-1
, lectin-like oxidized low-density lipoprotein receptor
, lectin-like oxidized LDL receptor-1
, oxidized low density lipoprotein receptor 1