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Oxysterols are byproducts of cholesterol that can have cytotoxic effects on many cell types. Additionally we are shipping Oxysterol Binding Protein 2 Proteins (4) and Oxysterol Binding Protein 2 Kits (2) and many more products for this protein.
Showing 10 out of 33 products:
Human Polyclonal OSBP2 Primary Antibody for ELISA, WB - ABIN185114
Moreira, Jaworski, Li, Rodriguez: Molecular and biochemical characterization of a novel oxysterol-binding protein (OSBP2) highly expressed in retina. in The Journal of biological chemistry 2001
ORP4 promotes the survival of rapidly proliferating cells.
Inhibition of HCV replication by oxysterol-binding protein-related protein 4 (ORP4) through interaction with HCV NS5B and alteration of lipid droplet formation.
In preliminary results, significantly higher levels of OSBP2 and OSBPL-7 (show OSBPL7 Antibodies) mRNA were seen in blood samples from cholangiocarcinoma patients than in healthy controls.
OSBP2 has a role in chronic myeloid leukemia (show BCL11A Antibodies)
Thus the sterol-binding domain of ORP4 binds vimentin (show VIM Antibodies), cholesterol and oxysterols, and interacts with the filamentous vimentin (show VIM Antibodies) network.
a possible role of OSBP2 gene in the pathogenesis of oxidative damage to the macula induced by oxysterols in age-related macular degeneration patients.
ORP4 is essential for the postmeiotic differentiation of germ cells
Oxysterols are byproducts of cholesterol that can have cytotoxic effects on many cell types. The membrane-bound protein encoded by this gene contains a pleckstrin homology (PH) domain and an oxysterol-binding region. It binds oxysterols such as 7-ketocholesterol and may inhibit their cytotoxicity. Alternate transcriptional splice variants have been observed but have not been fully characterized.
oxysterol-binding protein 2
, OSBP-related protein 4
, oxysterol binding protein-like 1
, oxysterol binding protein-related protein 4
, oxysterol-binding protein-related protein 4