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Osteoactivin Antibodies

(Osteoactivin (GPNMB))
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
anti-Osteoactivin (GPNMB) (AA 81-180) antibody anti-Osteoactivin (GPNMB) (AA 81-180) antibody anti-Osteoactivin (GPNMB) (AA 81-180) antibody (ABIN749093)

GPNMB Reactivity: Human, Mouse, Rat ELISA, IF (cc), IF (p), IHC (fro), IHC (p), WB Host: Rabbit Polyclonal unconjugated

anti-Osteoactivin (GPNMB) (AA 31-260) antibody anti-Osteoactivin (GPNMB) (AA 31-260) antibody anti-Osteoactivin (GPNMB) (AA 31-260) antibody (ABIN1724859)

GPNMB Reactivity: Human IHC, ELISA, WB Host: Mouse Monoclonal 7C10E5 unconjugated

anti-Osteoactivin (GPNMB) (N-Term) antibody anti-Osteoactivin (GPNMB) (N-Term) antibody anti-Osteoactivin (GPNMB) (N-Term) antibody (ABIN2781893)

GPNMB Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit IHC, WB Host: Rabbit Polyclonal unconjugated

Osteoactivin Antibodies by Reactivity

Find Osteoactivin Antibodies for a variety of species such as anti-Human Osteoactivin, anti-Mouse Osteoactivin, anti-Rat Osteoactivin. The species listed below are among those available. Click on a link to go to the corresponding products.

Osteoactivin Antibodies by Application

Find Osteoactivin Antibodies validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

Osteoactivin Antibodies by Host

Find Osteoactivin Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

Osteoactivin Antibodies by Binding Specificity

Find Osteoactivin Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

Osteoactivin Antibodies by Clonality

Find available monoclonal or polyclonal Osteoactivin Antibodies. Click on a link to go to the corresponding products.

Osteoactivin Antibodies by Clone

Find Osteoactivin Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

Osteoactivin Antibodies by Conjugate

Find Osteoactivin Antibodies with a specific conjugate such as Biotin, FITC, APC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular Osteoactivin Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (2)
  • (2)
Cat. No. ABIN523856
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC (p), WB
Validations
  • (2)
Cat. No. ABIN2855599
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB
Validations
  • (2)
Cat. No. ABIN2781894
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rat
Application WB
Validations
  • (2)
Cat. No. ABIN2781895
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application FACS, ICC, IF, IHC
Validations
  • (2)
Cat. No. ABIN5566465
Quantity 150 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (2)
Cat. No. ABIN3032103
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN564554
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN523857
Quantity 100 μg
Datasheet Datasheet

Application WB
Validations
  • (1)
Cat. No. ABIN6738123
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Hamster, Horse, Human, Mouse, Rabbit
Application IHC, IHC (p), WB
Validations
  • (1)
Cat. No. ABIN2621472
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application IHC (p), ELISA, WB
Validations
  • (1)
Cat. No. ABIN1723955
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IHC (p), WB
Validations
  • (1)
Cat. No. ABIN961423
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
Cat. No. ABIN7269117
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application ELISA
Validations
Cat. No. ABIN870731
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application EIA, RIA
Validations
Cat. No. ABIN5566461
Quantity 150 μg
Datasheet Datasheet

Latest Publications for our Osteoactivin Antibodies

Neal, Boyle, Budge, Safadi, Richardson: "The glycoprotein GPNMB attenuates astrocyte inflammatory responses through the CD44 receptor." in: Journal of neuroinflammation, Vol. 15, Issue 1, pp. 73, (2019) (PubMed).

Oyewumi, Manickavasagam, Novak, Wehrung, Paulic, Moussa, Sondag, Safadi: "Osteoactivin (GPNMB) ectodomain protein promotes growth and invasive behavior of human lung cancer cells." in: Oncotarget, Vol. 7, Issue 12, pp. 13932-44, (2017) (PubMed).

Arosarena, Dela Cadena, Denny, Bryant, Barr, Thorpe, Safadi: "Osteoactivin Promotes Migration of Oral Squamous Cell Carcinomas." in: Journal of cellular physiology, Vol. 231, Issue 8, pp. 1761-70, (2016) (PubMed).

Frara, Abdelmagid, Tytell, Amin, Popoff, Safadi, Barbe: "Growth and repair factors, osteoactivin, matrix metalloproteinase and heat shock protein 72, increase with resolution of inflammation in musculotendinous tissues in a rat model of repetitive grasping." in: BMC musculoskeletal disorders, Vol. 17, pp. 34, (2016) (PubMed).

Kramer, Wegdam, Donker-Koopman, Ottenhoff, Gaspar, Verhoek, Nelson, Gabriel, Kallemeijn, Boot, Laman, Vissers, Cox, Pavlova, Moran, Aerts, van Eijk: "Elevation of glycoprotein nonmetastatic melanoma protein B in type 1 Gaucher disease patients and mouse models." in: FEBS open bio, Vol. 6, Issue 9, pp. 902-13, (2016) (PubMed).

Ruan, Li, Nie, Zhou, Zou: "Differential expression of glycoprotein non-metastatic melanoma protein B (GPNMB) involved in trichostatin A-induced apoptosis in gastric cancer." in: International journal of clinical and experimental medicine, Vol. 7, Issue 12, pp. 4857-66, (2015) (PubMed).

Abdelmagid, Sondag, Moussa, Belcher, Yu, Stinnett, Novak, Mbimba, Khol, Hankenson, Malcuit, Safadi: "Mutation in Osteoactivin Promotes Receptor Activator of NF?B Ligand (RANKL)-mediated Osteoclast Differentiation and Survival but Inhibits Osteoclast Function." in: The Journal of biological chemistry, Vol. 290, Issue 33, pp. 20128-46, (2015) (PubMed).

Gutknecht, Geiger, Joas, Dörfel, Salih, Müller, Grünebach, Rittig: "The transcription factor MITF is a critical regulator of GPNMB expression in dendritic cells." in: Cell communication and signaling : CCS, Vol. 13, pp. 19, (2015) (PubMed).

Fiorentini, Bodei, Bedussi, Fragni, Bonini, Simeone, Zani, Berruti, Missale, Memo, Spano, Sigala: "GPNMB/OA protein increases the invasiveness of human metastatic prostate cancer cell lines DU145 and PC3 through MMP-2 and MMP-9 activity." in: Experimental cell research, Vol. 323, Issue 1, pp. 100-11, (2014) (PubMed).

Qin, Liu, Yuan, Zhang, Li, Zhang, Xu, Wang: "Glycoprotein non-metastatic melanoma protein B as a predictive prognostic factor in clear-cell renal cell carcinoma following radical nephrectomy." in: Molecular medicine reports, Vol. 9, Issue 3, pp. 851-6, (2014) (PubMed).

Aliases for Osteoactivin Antibodies

glycoprotein nmb (Gpnmb) Antibodies
glycoprotein nmb (GPNMB) Antibodies
glycoprotein (transmembrane) nmb (Gpnmb) Antibodies
glycoprotein nmb L homeolog (gpnmb.L) Antibodies
DC-HIL Antibodies
Dchil Antibodies
HGFIN Antibodies
ipd Antibodies
NMB Antibodies
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