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anti-Polypyrimidine Tract Binding Protein 2 (PTBP2) Antibodies

The protein encoded by PTBP2 binds to the intronic cluster of RNA regulatory elements, downstream control sequence (DCS). Additionally we are shipping Polypyrimidine Tract Binding Protein 2 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PTBP2 58155 Q9UKA9
PTBP2 56195 Q91Z31
PTBP2 310820 Q66H20
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Top anti-Polypyrimidine Tract Binding Protein 2 Antibodies at antibodies-online.com

Showing 10 out of 57 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PTBP2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: PANC1 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PTBP2 Antibody Titration: 1.25ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$221.76
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated ELISA, WB PTBP2 monoclonal antibody (M01), clone 2D10-B2 Western Blot analysis of PTBP2 expression in IMR-32 . PTBP2 monoclonal antibody (M01), clone 2D10-B2. Western Blot analysis of PTBP2 expression in human brain membrane (lane 1) and human brain cortex (lane 2). 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (84.63 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Goat Un-conjugated IHC, ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Mouse Un-conjugated WB PTBP2 monoclonal antibody (M09), clone 2B11. Western Blot analysis of PTBP2 expression in Hela NE. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated WB PTBP2 monoclonal antibody (M01), clone 2D10-B2 Western Blot analysis of PTBP2 expression in IMR-32. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated IP, WB 100 μL Log in to see 14 Days
$527.15
Details

PTBP2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Polypyrimidine Tract Binding Protein 2 Antibodies

  1. Human Polyclonal PTBP2 Primary Antibody for ELISA, WB - ABIN566177 : Rolland, Evrard, Guitton, Lavigne, Calvel, Couvet, Jégou, Pineau: Two-dimensional fluorescence difference gel electrophoresis analysis of spermatogenesis in the rat. in Journal of proteome research 2007 (PubMed)
    Show all 6 references for ABIN566177

  2. Cow (Bovine) Polyclonal PTBP2 Primary Antibody for WB - ABIN2776546 : Galbán, Kuwano, Pullmann, Martindale, Kim, Lal, Abdelmohsen, Yang, Dang, Liu, Lewis, Holcik, Gorospe: RNA-binding proteins HuR and PTB promote the translation of hypoxia-inducible factor 1alpha. in Molecular and cellular biology 2007 (PubMed)

  3. Human Monoclonal PTBP2 Primary Antibody for ELISA, WB - ABIN566178 : Xue, Zhou, Wu, Zhu, Ji, Kwon, Zhang, Yeo, Black, Sun, Fu, Zhang: Genome-wide analysis of PTB-RNA interactions reveals a strategy used by the general splicing repressor to modulate exon inclusion or skipping. in Molecular cell 2010 (PubMed)

  4. Cow (Bovine) Polyclonal PTBP2 Primary Antibody for WB - ABIN2776545 : Tateiwa, Gotoh, Ichikawa, Kikuchi, Yoshimura: Molecular cloning and characterization of human PTB-like protein: a possible retinal autoantigen of cancer-associated retinopathy. in Journal of neuroimmunology 2001 (PubMed)

  5. Human Polyclonal PTBP2 Primary Antibody for ELISA, WB - ABIN238583 : Boutz, Stoilov, Li, Lin, Chawla, Ostrow, Shiue, Ares, Black: A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons. in Genes & development 2007 (PubMed)

More Antibodies against Polypyrimidine Tract Binding Protein 2 Interaction Partners

Human Polypyrimidine Tract Binding Protein 2 (PTBP2) interaction partners

  1. PTBP1 (show PTBP1 Antibodies) and PTBP2 impaired autoregulation of SRSF3 (show SRSF3 Antibodies) in oral squamous cell carcinoma cancer cells.

  2. Data show that polypyrimidine tract-binding (show PTBP1 Antibodies) proteins nPTB and ROD1 (show PTBP3 Antibodies) interact with mitochondrial tRNA(Thr (show TRH Antibodies)) in the cytoplasm outside of mitochondria.

  3. In T98G glioma cells, the level of sumoylated PTBP2 was reduced compared to that of normal brain cells. Overall, this study shows that PTBP2 is posttranslationally modified by SUMO1 (show SUMO1 Antibodies).

  4. MALAT1 binds to SFPQ (show SFPQ Antibodies) releasing PTBP2 from the SFPQ (show SFPQ Antibodies)/PTBP2 complex, the increased SFPQ (show SFPQ Antibodies)-detached PTBP2 promotes cell proliferation and migration in colorectal cancer.

  5. Defining the multifunctional roles of PTB (show PTBP1 Antibodies) will contribute to the understanding of key regulatory events in gene expression.

  6. Changes in miR (show MLXIP Antibodies)-223/PTBP2 pathway could contribute of abnormal splicing in chronic myeloid leukemia (show BCL11A Antibodies).

  7. Regulation of the mutually exclusive exons 8a and 8 in the CaV1.2 (show CACNA1C Antibodies) calcium channel transcript by polypyrimidine tract-binding protein (show PTBP1 Antibodies).

  8. present fluorescence, NMR, and in vivo splicing data in support of a role of PTB (show PTBP1 Antibodies) in inducing RNA loops. We show that the RNA recognition motifs (RRMs) 3 and 4 of PTB (show PTBP1 Antibodies) can bind two distant pyrimidine tracts and bring their 5' and 3' ends in close proximity

  9. The nPTB proximal promoter, although rich in G+C content and presenting putative binding sites for the transcription factors Sp1 (show PSG1 Antibodies), NF-1 (show NF1 Antibodies), NF-kB and Oct-1 (show POU2F1 Antibodies), lacks a typical TATA box.

  10. Study shows that PTB (show PTBP1 Antibodies) can function as an anti-repressor molecule to counteract the splicing inhibitory activity of SRp30c (show SFRS9 Antibodies).

Mouse (Murine) Polypyrimidine Tract Binding Protein 2 (PTBP2) interaction partners

  1. Ptbp2 ablation results in germ cell loss due to increased apoptosis of meiotic spermatocytes and postmeiotic arrest of spermatid differentiation.

  2. These results define a new genetic regulatory program, where PTBP2 acts to temporarily repress expression of adult protein isoforms until the final maturation of the neuron.

  3. Thus, Ptbp2 inhibition of a discrete set of adult neuronal exons underlies early brain development prior to neuronal differentiation and is essential for postnatal survival.

  4. The expression of PSD-95 (show DLG4 Antibodies) during early neural development is controlled at the RNA level by two PTB (show PTBP1 Antibodies) proteins whose sequential downregulation is necessary for synapse maturation.

  5. The present study provides evidence that alternative neuronal nPTB and Fox-1 (show A2BP1 Antibodies)/Fox-2 (show RBM9 Antibodies) isoforms are also produced in lenses

  6. Regulation of the mutually exclusive exons 8a and 8 in the CaV1.2 (show CACNA1C Antibodies) calcium channel transcript by polypyrimidine tract-binding protein (show PTBP1 Antibodies).

  7. Reduction of PTBP2 levels led to decreases in 7 of 10 of the mRNAs, to the repression of alternative splicing of introns, and to reductions in specific miRNAs.

  8. The predominant expression of REST4, HuB/C/D and nPTB in post-mitotic fiber cells, together with miR (show MLXIP Antibodies)-124 expression in vertebrate lenses, was shown.

  9. PTBP2 is a trans-acting factor that helps to stabilize Pgk2 (show PGK2 Antibodies) mRNA in male mouse germ cells.

  10. The post-transcriptional switch from PTB (show PTBP1 Antibodies) to nPTB controls a widespread alternative splicing program during neuronal development.

Zebrafish Polypyrimidine Tract Binding Protein 2 (PTBP2) interaction partners

  1. Two stretches of polypyrimidine tracts designated PPT1 and PPT2 which influence the IRES activity of cx55.5 protein were identified; deletion of PPT2 results in a complete loss of the IRES activity

Polypyrimidine Tract Binding Protein 2 (PTBP2) Antigen Profile

Protein Summary

The protein encoded by this gene binds to the intronic cluster of RNA regulatory elements, downstream control sequence (DCS). It is implicated in controlling the assembly of other splicing-regulatory proteins. This protein is very similar to the polypyrimidine tract binding protein but it is expressed primarily in the brain.

Gene names and symbols associated with PTBP2

  • polypyrimidine tract binding protein 2 (PTBP2) antibody
  • polypyrimidine tract binding protein 2 (LOC100349676) antibody
  • polypyrimidine tract binding protein 2 (Ptbp2) antibody
  • polypyrimidine tract binding protein 2b (ptbp2b) antibody
  • brPTB antibody
  • im:7153495 antibody
  • nPTB antibody
  • nPTB5 antibody
  • nPTB6 antibody
  • nPTB7 antibody
  • nPTB8 antibody
  • PTB antibody
  • Ptb2 antibody
  • PTBLP antibody
  • ptbp2 antibody
  • si:ch211-160l17.2 antibody
  • wu:fa08f05 antibody
  • wu:fc05d10 antibody

Protein level used designations for PTBP2

polypyrimidine tract binding protein 2 , polypyrimidine tract-binding protein 2-like , PTB-like protein , neural polypyrimidine tract binding protein , neural polypyrimidine tract-binding protein , neurally-enriched homolog of PTB , polypyrimidine tract-binding protein 2 , splicing regulator , RRM-type RNA-binding protein brPTB , brain-enriched PTB , brain-enriched polypyrimidine tract-binding protein

GENE ID SPECIES
424479 Gallus gallus
457046 Pan troglodytes
100349676 Oryctolagus cuniculus
100435447 Pongo abelii
100603151 Nomascus leucogenys
58155 Homo sapiens
537341 Bos taurus
56195 Mus musculus
310820 Rattus norvegicus
562434 Danio rerio
490149 Canis lupus familiaris
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