PTBP2 antibody (N-Term)

Catalog No. ABIN2776545

There is 1 publication for this product available. The Rabbit Polyclonal anti-PTBP2 antibody is suitable to detect PTBP2 in samples from Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Cow and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for PTBP2 antibody (N-Term) (ABIN2776545)

Target: PTBP2 (Polypyrimidine Tract Binding Protein 2 (PTBP2))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTBP2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PTBP2 Antibody

Binding Specificity: N-Term

Purpose: PTBP2 Antibody - N-terminal region

Sequence: MDGIVTEVAV GVKRGSDELL SGSVLSSPNS NMSSMVVTAN GNDSKKFKGE

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against PTBP2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PTBP2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40965-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-PTBP2 antibody (ABIN2776545)

Tateiwa, Gotoh, Ichikawa, Kikuchi, Yoshimura: "Molecular cloning and characterization of human PTB-like protein: a possible retinal autoantigen of cancer-associated retinopathy." in: Journal of neuroimmunology, Vol. 120, Issue 1-2, pp. 161-9, (2001) (PubMed).

Target Details for PTBP2

Target: PTBP2 (Polypyrimidine Tract Binding Protein 2 (PTBP2))

Alternative Name: PTBP2

Background:

Background Information: PTBP2 binds to the intronic cluster of RNA regulatory elements, downstream control sequence (DCS). It is implicated in controlling the assembly of other splicing-regulatory proteins. This protein is very similar to the polypyrimidine tract binding protein but it is expressed primarily in the brain.

Gene Name: Polypyrimidine tract binding protein 2

Alternative Symbols: nPTB, PTBLP, brPTB

Protein Name: Polypyrimidine tract-binding protein 2

Molecular Weight: 40kDa

Gene ID: 58155

UniProt: Q9UKA9

Pathways: Ribonucleoprotein Complex Subunit Organization, SARS-CoV-2 Protein Interactome