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anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 2 (KCNJ2) Antibodies

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. Additionally we are shipping KCNJ2 Proteins (5) and KCNJ2 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KCNJ2 3759 P63252
KCNJ2 29712 Q64273
KCNJ2 16518 P35561
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Top anti-KCNJ2 Antibodies at antibodies-online.com

Showing 10 out of 89 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated ICC, IF, IHC, WB Kir2 1 Rat Brain Membranes Western Blotting. Kir2 Mouse backskin. 100 μg Log in to see 3 to 4 Days
$383.90
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue, using KCNJ2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse HRP ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$422.40
Details
Human Mouse FITC ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$426.80
Details
Human Mouse Alkaline Phosphatase (AP) ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$429.00
Details
Human Mouse Biotin ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$431.20
Details
Human Mouse PE ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$432.30
Details
Human Mouse Streptavidin ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$433.40
Details
Human Mouse APC ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$434.50
Details
Human Mouse PerCP ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$434.50
Details

KCNJ2 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-KCNJ2 Antibodies

  1. Human Monoclonal KCNJ2 Primary Antibody for ICC, IF - ABIN2483544 : Donaldson, Yoon, Fu, Ptacek: Andersen-Tawil syndrome: a model of clinical variability, pleiotropy, and genetic heterogeneity. in Annals of medicine 2004 (PubMed)

  2. Human Polyclonal KCNJ2 Primary Antibody for IHC, ELISA - ABIN1534992 : Wood, Tsai, Lee, Vogeli: Cloning and functional expression of a human gene, hIRK1, encoding the heart inward rectifier K+-channel. in Gene 1995 (PubMed)

More Antibodies against KCNJ2 Interaction Partners

Human Potassium Inwardly-Rectifying Channel, Subfamily J, Member 2 (KCNJ2) interaction partners

  1. Variability has been found in a three-generation family with Pierre Robin sequence, acampomelic campomelic dysplasia, and intellectual disability due to a novel approximately 1 Mb deletion upstream of SOX9 (show SOX9 Antibodies), and including KCNJ2 and KCNJ16 (show KCNJ16 Antibodies).

  2. Patients with Dilated Cardiomyopathy and Sustained Monomorphic Ventricular Tachycardia Show Up-Regulation of KCNN3 (show KCNN3 Antibodies) and KCNJ2 Genes and CACNG8 (show CACNG8 Antibodies)-Linked Left Ventricular Dysfunction

  3. Results indicate that silencing BKCa (KCa1.1 (show KCNMA1 Antibodies)) inhibits cell mobility, while silencing IKir (Kir2.1) increases cell mobility in human cardiac c-kit (show KIT Antibodies)+ progenitor cells.

  4. No genetic variants were identified in the KCNJ2 gene in this cohort of Chinese thyrotoxic periodic paralysis patients.

  5. Kir2.1 channels exhibit a binding site determined by Cys311 that is responsible for drug-induced increases in inward rectifier Kir2.1 currents.

  6. Kir2.1 channel function is essential during osteoblastogenesis.

  7. Upregulation of the inwardly rectifying potassium channel Kir2.1 (KCNJ2) modulates multidrug resistance of small-cell lung cancer under the regulation of miR-7 (show LILRB1 Antibodies) and the Ras/MAPK (show MAPK1 Antibodies) pathway.

  8. propose that Kir2.1 currents control the interspike interval, and predict that blocking Kir2.1 channels increases the action potential frequency, which should augment the rate of insulin (show INS Antibodies) secretion in pancreatic beta cells

  9. Results show that K346T mutation causes gain of function of the Kir2.1 channels by altering their trafficking and stabilization suggesting that the variant has a combined effect on cardiac rhythm and neuropsychiatric phenotype.

  10. This study demonistrated that KCNJ2 mutations cause a variable phenotype, with dysmorphic features seen in all patients studied, a high penetrance of periodic paralysis in males and ventricular arrhythmia with a risk of sudden cardiac death.

Mouse (Murine) Potassium Inwardly-Rectifying Channel, Subfamily J, Member 2 (KCNJ2) interaction partners

  1. Consistent with a role of the K(+) current in amplifying the sensory response, entry of protons through the Zn(2+)-sensitive conductance produces a transient block of the KIR2.1 current.

  2. Mouse neutrophils express functional Kir2.1 channels from bone marrow and liver.

  3. A184R mutation in the inner end of the bundle crossing region of Kir2.1 not only abolishes the inward rectifying features of spermine block but also tends to close the channel pore.

  4. the present work demonstrates that a functional Kir2.1-like channel is expressed in lactating mouse mammary secretory cells.

  5. Kir2.1 mRNA levels were downregulated by LPS (show TLR4 Antibodies), and to a lesser extent by IL-4 (show IL4 Antibodies)/IL-13 (show IL13 Antibodies).

  6. Report pentamidine analogue which specifically blocks cardiac KIR2.1 channel, lengthening action potential duration.

  7. The total Kcnj2 (gene for the Kir2.1 potassium channel (show KCNAB2 Antibodies)) mRNA was reduced in Huntington disease (show HTT Antibodies) skeletal muscle.

  8. miR (show MLXIP Antibodies)-26 controls the expression of KCNJ2 and may have a role in atrial fibrillation

  9. Stronger expressions of SCN5a (show SCN5A Antibodies), SCN1b (show SCN1B Antibodies) and Kir2.1 were observed in ventricular-like and atrial-like cells compared to that of pacemaker-like cardiomyocytes.

  10. The data of this study suggested that Kir2.1 is required for I(K1) in type II utricle hair cells.

Cow (Bovine) Potassium Inwardly-Rectifying Channel, Subfamily J, Member 2 (KCNJ2) interaction partners

  1. Kir2.1 may mediate native Kir (show GEM Antibodies) currents responsible for setting resting membrane potential in bovine parotid cells and might be, at least in part, involved in spontaneous secretion in ruminant parotid glands.

Rabbit Potassium Inwardly-Rectifying Channel, Subfamily J, Member 2 (KCNJ2) interaction partners

  1. There were substantial transmural gradients in Cav1.2 (show CACNA1C Antibodies), KChIP2 (show KCNIP2 Antibodies), ERG (show KCNH2 Antibodies), KvLQT1 (show KCNQ1 Antibodies), Kir2.1, NCX1 (show SLC8A1 Antibodies), SERCA2a (show ATP2A2 Antibodies) and RyR2 (show RYR2 Antibodies) at the mRNA and, in some cases, protein level-in every case the mRNA or protein was more abundant in the epicardium than the endocardium.

KCNJ2 Antigen Profile

Protein Summary

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Mutations in this gene have been associated with Andersen syndrome, which is characterized by periodic paralysis, cardiac arrhythmias, and dysmorphic features.

Gene names and symbols associated with KCNJ2

  • inward rectifier potassium channel (IRK1) antibody
  • potassium inwardly-rectifying channel, subfamily J, member 2 (KCNJ2) antibody
  • potassium inwardly-rectifying channel, subfamily J, member 2 (Kcnj2) antibody
  • ATFB9 antibody
  • HHBIRK1 antibody
  • HHIRK1 antibody
  • IRK-1 antibody
  • IRK1 antibody
  • Kcnf1 antibody
  • KCNJ2 antibody
  • Kir2.1 antibody
  • LQT7 antibody
  • SQT3 antibody

Protein level used designations for KCNJ2

IRK-1 , inward rectifier K(+) channel Kir2.1 , inward rectifier potassium channel 2 , potassium channel, inwardly rectifying subfamily J member 2 , cardiac inward rectifier potassium channel , hIRK1 , inward rectifier K+ channel KIR2.1 , RBL-IRK1 , BIK , inward rectifier potassium channel cIRK1 , cardiac inward rectifier KIR2.1 , inwardly rectifying potassium channel Kir2.1 , inward rectifier potassium channel Kir2.1 , inwardly-rectifying potassium channel Kir2.1

GENE ID SPECIES
397293 Sus scrofa
3759 Homo sapiens
29712 Rattus norvegicus
16518 Mus musculus
281883 Bos taurus
396328 Gallus gallus
403717 Canis lupus familiaris
100135566 Cavia porcellus
100008987 Oryctolagus cuniculus
574189 Macaca mulatta
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