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May have a role in the regulation of spermatogenesis.. Additionally we are shipping PD-1 Antibodies (426) and PD-1 Proteins (71) and many more products for this protein.
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Human PD-1 ELISA Kit for Sandwich ELISA - ABIN1672863
Day, Kaufmann, Kiepiela, Brown, Moodley, Reddy, Mackey, Miller, Leslie, DePierres, Mncube, Duraiswamy, Zhu, Eichbaum, Altfeld, Wherry, Coovadia, Goulder, Klenerman, Ahmed, Freeman, Walker: PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. in Nature 2006
Show all 2 references for ABIN1672863
expression of PD-1 identifies a diverse and patient-specific antitumor T cell response in peripheral blood, providing a novel noninvasive strategy to develop personalized therapies using neoantigen-reactive lymphocytes or TCRs to treat cancer
PDCD1 single nucleotide genes polymorphisms confer susceptibility to juvenile-onset systemic lupus erythematosus.
Data suggest signaling via CD279/PDCD1 and its ligand CD274/PD-L1 (show CD274 ELISA Kits) is effective chemotherapy target in non-small cell lung cancer; PD-L1 (show CD274 ELISA Kits) is best currently available immunohistochemistry biomarker for response to immune checkpoint inhibitors. [REVIEW]
After stimulation, a defect in T regulatory cell proliferation was observed in diabetics and the percentages of total PD-1, PD-1low and PD-1high expressing cells were lower in patients.
Binding of PD-L1 (show CD274 ELISA Kits) to PD-1 causes inhibition of T-cell proliferation and cytokine release. Read More: http://www.atsjournals.org/doi/full/10.1164/rccm.201504-0782OC#.V5gEONLrtNs
Studies indicate that program death receptor-1 (PD-1) blockade represents successful mismatch repair (MMR (show MRC1 ELISA Kits))-deficient tumor therapy.
genetic mechanism of tumor immune escape caused by structural variations commonly disrupting the 3' region of the PD-L1 (show CD274 ELISA Kits) gene
feasibility of using anti-PD-L1 (show CD274 ELISA Kits) antibody for radionuclide imaging and radioimmunotherapy and highlight a new opportunity to optimize and monitor the efficacy of immune checkpoint inhibition therapy.
The patients with chronic renal allograft rejection have a characteristic increase in circulating Tfh cells with a decrease in PD-1 expression.
Oncogenic activation of the AKT (show AKT1 ELISA Kits)-mTOR (show FRAP1 ELISA Kits) pathway promotes immune escape by driving expression of PD-L1 (show CD274 ELISA Kits).
LAG3 (show LAG3 ELISA Kits) and PD1 co-inhibitory molecules have roles in collaborating to limit CD8 (show CD8A ELISA Kits)+ T cell signaling and dampen antitumor immunity in a murine ovarian cancer model
Decidual NK, NKT (show CTSL1 ELISA Kits) and gamma/delta T cells showed increased PD-1 expression and reduced cytotoxic potential when compared to the periphery.
The endogenous PD-1/PD-L pathway does not limit acute experimental foreign antigen-induced circulating immune complex glomerulonephritis.
AE2 (show SLC4A2 ELISA Kits) deficiency results in intrahepatic T-cell activation and PD-1/PD-L1 (show CD274 ELISA Kits) mediated deletion, favoring autoimmune cholangitis.
Burkholderia pseudomallei appears to upregulate the expression of PD-1 on T cells to evade host immune responses, which likely facilitates bacterial persistence in the host.
increased programmed death-1 signaling pathway expression by conventional natural killer cells promotes host protection at the intestinal mucosa during acute infection with a bacterial gut (show GUSB ELISA Kits) pathogen.
Poxvirus-Based Active Immunotherapy with PD-1 and LAG-3 (show LAG3 ELISA Kits) Dual Immune Checkpoint Inhibition Overcomes Compensatory Immune Regulation, Yielding Complete Tumor Regression in Mice.
The results demonstrated that blockade of PD-1/B7H1 (show CD274 ELISA Kits) pathway could promote mouse NK cells to kill the GL261GSCs, and the PD-1-inhibited NK cells could be a feasible immune therapeutic approach against Glioblastoma multiforme.
Upregulation of PD-1 and PD-L1 (show CD274 ELISA Kits) was associated with marked increases in GADD153 (show DDIT3 ELISA Kits) during myocardial ischemic reperfusion injury
May have a role in the regulation of spermatogenesis.
programmed cell death 1
, programmed cell death protein 1
, protein PD-1
, programmed death 1
, spermatogenesis associated PD1
, spermatogenesis-associated protein 2
, spermatogenesis-associated protein PD1