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May have a role in the regulation of spermatogenesis.. Additionally we are shipping PD-1 Antibodies (426) and PD-1 Proteins (71) and many more products for this protein.
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Human PD-1 ELISA Kit for Sandwich ELISA - ABIN1672863
Day, Kaufmann, Kiepiela, Brown, Moodley, Reddy, Mackey, Miller, Leslie, DePierres, Mncube, Duraiswamy, Zhu, Eichbaum, Altfeld, Wherry, Coovadia, Goulder, Klenerman, Ahmed, Freeman, Walker: PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. in Nature 2006
Show all 2 references for ABIN1672863
Pulmonary LELC have remarkably high incidence of PD-L1 (show CD274 ELISA Kits) expression. PD-L1 (show CD274 ELISA Kits) was a negative prognostic factor for DFS (show FST ELISA Kits) in surgically resected pulmonary LELC.
High PD-1 expression is associated with brain metastases.
PD-1 regulates peripheral T-cell responses in both human and murine rheumatoid arthritis
PD-1 might be an independent, universal marker of CLL cells and a part of their activated phenotype, and subsequently might modulate the function of ZAP-70 (show ZAP70 ELISA Kits).
expression of PD-1 identifies a diverse and patient-specific antitumor T cell response in peripheral blood, providing a novel noninvasive strategy to develop personalized therapies using neoantigen-reactive lymphocytes or TCRs to treat cancer
PDCD1 single nucleotide genes polymorphisms confer susceptibility to juvenile-onset systemic lupus erythematosus.
Data suggest signaling via CD279/PDCD1 and its ligand CD274/PD-L1 (show CD274 ELISA Kits) is effective chemotherapy target in non-small cell lung cancer; PD-L1 (show CD274 ELISA Kits) is best currently available immunohistochemistry biomarker for response to immune checkpoint inhibitors. [REVIEW]
After stimulation, a defect in T regulatory cell proliferation was observed in diabetics and the percentages of total PD-1, PD-1low and PD-1high expressing cells were lower in patients.
Binding of PD-L1 (show CD274 ELISA Kits) to PD-1 causes inhibition of T-cell proliferation and cytokine release. Read More: http://www.atsjournals.org/doi/full/10.1164/rccm.201504-0782OC#.V5gEONLrtNs
Studies indicate that program death receptor-1 (PD-1) blockade represents successful mismatch repair (MMR (show MRC1 ELISA Kits))-deficient tumor therapy.
LAG3 (show LAG3 ELISA Kits) and PD1 co-inhibitory molecules have roles in collaborating to limit CD8 (show CD8A ELISA Kits)+ T cell signaling and dampen antitumor immunity in a murine ovarian cancer model
Decidual NK, NKT (show CTSL1 ELISA Kits) and gamma/delta T cells showed increased PD-1 expression and reduced cytotoxic potential when compared to the periphery.
The endogenous PD-1/PD-L pathway does not limit acute experimental foreign antigen-induced circulating immune complex glomerulonephritis.
AE2 (show SLC4A2 ELISA Kits) deficiency results in intrahepatic T-cell activation and PD-1/PD-L1 (show CD274 ELISA Kits) mediated deletion, favoring autoimmune cholangitis.
Burkholderia pseudomallei appears to upregulate the expression of PD-1 on T cells to evade host immune responses, which likely facilitates bacterial persistence in the host.
increased programmed death-1 signaling pathway expression by conventional natural killer cells promotes host protection at the intestinal mucosa during acute infection with a bacterial gut (show GUSB ELISA Kits) pathogen.
Poxvirus-Based Active Immunotherapy with PD-1 and LAG-3 (show LAG3 ELISA Kits) Dual Immune Checkpoint Inhibition Overcomes Compensatory Immune Regulation, Yielding Complete Tumor Regression in Mice.
genetic mechanism of tumor immune escape caused by structural variations commonly disrupting the 3' region of the PD-L1 (show CD274 ELISA Kits) gene
The results demonstrated that blockade of PD-1/B7H1 (show CD274 ELISA Kits) pathway could promote mouse NK cells to kill the GL261GSCs, and the PD-1-inhibited NK cells could be a feasible immune therapeutic approach against Glioblastoma multiforme.
May have a role in the regulation of spermatogenesis.
programmed cell death 1
, programmed cell death protein 1
, protein PD-1
, programmed death 1
, spermatogenesis associated PD1
, spermatogenesis-associated protein 2
, spermatogenesis-associated protein PD1