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May have a role in the regulation of spermatogenesis.. Additionally we are shipping PD-1 Antibodies (579) and PD-1 Proteins (75) and many more products for this protein.
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Human PD-1 ELISA Kit for Sandwich ELISA - ABIN1672863
Day, Kaufmann, Kiepiela, Brown, Moodley, Reddy, Mackey, Miller, Leslie, DePierres, Mncube, Duraiswamy, Zhu, Eichbaum, Altfeld, Wherry, Coovadia, Goulder, Klenerman, Ahmed, Freeman, Walker: PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. in Nature 2006
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Based on the PD-L1 (show CD274 ELISA Kits) receptor PD-1 expression on tumor-infiltrating cytotoxic cells, our data supported that expression of PD-L1 (show CD274 ELISA Kits) on TAM (show CCNA1 ELISA Kits) promoted apoptosis of T cells via interaction with PD-1 on CD8 (show CD8A ELISA Kits)(+)T cells.
The incidence of PD-1 inhibitor-related pneumonitis was higher in non-small cell lung cancer and renal cell carcinoma during combination therapy. These findings contribute to enhance awareness among clinicians and support further investigations to meet the clinical needs
Our findings support an association between the PD-1 rs2227982 polymorphism and decreased breast cancer risk, especially in Her-2 (show ERBB2 ELISA Kits) positive breast cancer patients in the Chinese population.
High PD-1 expression is associated with Hodgkin's lymphoma.
Our study revealed that RANK-L is a promising marker to forecast pts (show PTS ELISA Kits)' prognosis in AML (show RUNX1 ELISA Kits). Immune checkpoint receptor PD-1/L as well as RANK and HLA-ABC (show ABCB6 ELISA Kits) did not show an impact on pts (show PTS ELISA Kits)' survival.
The PD-1/PD-L1 (show CD274 ELISA Kits) checkpoint blockade, which targets regulatory pathways in T cells to overcome immune resistance, is correlated to PD-L1 (show CD274 ELISA Kits) expression pattern and the presence of tumor-infiltrating lymphocytes (TILs). Meanwhile, immunogenic mutation loads show significant response to checkpoint blockade, which is probably due to PD-1/L1 status and TIL (show TLR1 ELISA Kits) content
The expression rate of PDCD1 in extranodal NK/T-cell lymphoma patients was very low.
Study demonstrates that PD-1(+) TIMC and intratumoral PD-L1 (show CD274 ELISA Kits)(+) expression did not significantly impact tumor aggressiveness or clinical outcome in non-ccRCC specimens.
Immune surveillance is an important mechanism in prevention of cancer development and inhibition of growth of tumors and metastasis. Checkpoint pathways prevent immune response through multiple methods including CTLA-4 (show CTLA4 ELISA Kits) and PD-1/PD-L1 (show CD274 ELISA Kits) pathways.A variety of immune checkpoint inhibitors (PD-1/PD-L1 (show CD274 ELISA Kits) and CTLA-4 (show CTLA4 ELISA Kits) inhibitors) have been studied in recurrent and metastatic head and neck cancers with encouraging efficacy
n combination with anti-PD-1/PD-L1 (show CD274 ELISA Kits), the CTLA-4 (show CTLA4 ELISA Kits)-expanded T cells are prevented from being functionally inhibited when they enter into the tumor microenvironment.
Tim-3 (show HAVCR2 ELISA Kits)(+) PD-1(+) CD8 (show CD8A ELISA Kits)(+) T cells showed more evident properties associated with exhaustion than Tim-3 (show HAVCR2 ELISA Kits)(-) PD-1(+) CD8 (show CD8A ELISA Kits)(+) T cells.
that porcine islet-specific tolerance is dependent on PD-1, which could not be extended to skin grafts
Programmed cell death-1 engagement followed by zymosan stimulation might primarily attenuate the phosphorylation of tyrosine residue in Programmed cell death-1 receptor/ligand.
Study suggests that expression of the inhibitory receptors PD-1 and LAG-3 (show LAG3 ELISA Kits) on CD4 (show CD4 ELISA Kits)(+) T cells and their reduced IL-2 (show IL2 ELISA Kits) production are common characteristic features of Plasmodium infection.
these data suggest a scenario in which microglia are involved in the regulation of experimental autoimmune encephalomyelitis by suppressing Th1 (show HAND1 ELISA Kits)-cell differentiation via the PD-L1 (show CD274 ELISA Kits)-nitric oxide pathway.
Blockade of TGFbeta (show TGFB1 ELISA Kits) downregulated PD-1 and PD-L1 (show CD274 ELISA Kits) expression and precipitated graft rejection.
PD-1 regulates peripheral T-cell responses in both human and murine rheumatoid arthritis
LAG3 (show LAG3 ELISA Kits) and PD1 co-inhibitory molecules have roles in collaborating to limit CD8 (show CD8A ELISA Kits)+ T cell signaling and dampen antitumor immunity in a murine ovarian cancer model
Decidual NK, NKT (show CTSL1 ELISA Kits) and gamma/delta T cells showed increased PD-1 expression and reduced cytotoxic potential when compared to the periphery.
The endogenous PD-1/PD-L pathway does not limit acute experimental foreign antigen-induced circulating immune complex glomerulonephritis.
May have a role in the regulation of spermatogenesis.
programmed cell death 1
, programmed cell death protein 1
, protein PD-1
, programmed death 1
, spermatogenesis associated PD1
, spermatogenesis-associated protein 2
, spermatogenesis-associated protein PD1