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anti-Protein Kinase D3 (PRKD3) Antibodies

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. Additionally we are shipping Protein Kinase D3 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PRKD3 5312  
PRKD3 75292 Q8K1Y2
PRKD3 313834  
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Top anti-Protein Kinase D3 Antibodies at antibodies-online.com

Showing 10 out of 108 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-PKCnu C-term Pab (ABIN391015) in NCI-H46... Upper panel, western blot analysis of GFP fusion protein expression in... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of Prkd3 (arrow) using rabbit polyclonal Mouse P... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF, IHC (p), WB TOP: Upper panel, western blot analysis of GFP fusion protein expressi... Western blot analysis of anti-PKCnu Pab in lysate of HL60 cells stimul... 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-PKCnu Pab (ABIN391014) in lysate of HL60... Upper panel, western blot analysis of GFP fusion protein expression in... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF, IHC (p), WB TOP: Upper panel, western blot analysis of GFP fusion protein expressi... Western blot analysis of anti-PKCnu C-term Pab in NCI-H460 cell lysate... 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged PRKD3 is approximately 1ng/... Western Blot detection against Immunogen (36.63 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human colon carcinoma labeled wit... Formalin-fixed and paraffin embedded rat kidney tissue labeled with An... 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 8 to 10 Days
$463.83
Details
Human Rabbit Un-conjugated IP, WB   100 μL Log in to see 8 to 10 Days
$683.83
Details
Human Rabbit Un-conjugated IHC, WB 400 μL Log in to see 6 Days
$457.14
Details

PRKD3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
,
Mouse (Murine) , , , ,

Rat (Rattus) , , , ,

Top referenced anti-Protein Kinase D3 Antibodies

  1. Human Polyclonal PRKD3 Primary Antibody for IF, IHC (p) - ABIN359071 : Yeaman, Ayala, Wright, Bard, Bossard, Ang, Maeda, Seufferlein, Mellman, Nelson, Malhotra: Protein kinase D regulates basolateral membrane protein exit from trans-Golgi network. in Nature cell biology 2004 (PubMed)
    Show all 6 references for ABIN359071

  2. Human Polyclonal PRKD3 Primary Antibody for IF, IHC (p) - ABIN359072 : Rey, Yuan, Young, Rozengurt: Protein kinase C nu/protein kinase D3 nuclear localization, catalytic activation, and intracellular redistribution in response to G protein-coupled receptor agonists. in The Journal of biological chemistry 2003 (PubMed)
    Show all 5 references for ABIN359072

  3. Human Polyclonal PRKD3 Primary Antibody for IHC (p), WB - ABIN391014 : Matthews, Dayalu, Thompson, Scharenberg: Regulation of protein kinase Cnu by the B-cell antigen receptor. in The Journal of biological chemistry 2003 (PubMed)
    Show all 4 references for ABIN391014

  4. Human Polyclonal PRKD3 Primary Antibody for IHC (p), WB - ABIN658062 : Ellwanger, Pfizenmaier, Lutz, Hausser: Expression patterns of protein kinase D 3 during mouse development. in BMC developmental biology 2008 (PubMed)
    Show all 2 references for ABIN658062

  5. Human Monoclonal PRKD3 Primary Antibody for ELISA, WB - ABIN565151 : Borges, Döppler, Perez, Andorfer, Sun, Anastasiadis, Thompson, Geiger, Storz: Pharmacologic reversion of epigenetic silencing of the PRKD1 promoter blocks breast tumor cell invasion and metastasis. in Breast cancer research : BCR 2014 (PubMed)

More Antibodies against Protein Kinase D3 Interaction Partners

Human Protein Kinase D3 (PRKD3) interaction partners

  1. Data show that similar to a knockdown of serine/threonine kinase (show TLK2 Antibodies) protein kinase D3 (PKD3), treatment with this inhibitor targets all tumorigenic processes in vitro and decreases growth of primary tumors and metastasis in vivo

  2. Studies indicate that the loss of protein kinase D PKD1 is thought to promote invasion and metastasis, while PKD2 (show PKD2 Antibodies) and upregulated PKD3 to be positive regulators of proliferation.

  3. Loss of PKD2 (show PKD2 Antibodies) enhanced KC proliferative potential while loss of PKD3 resulted in a progressive proliferation defect, loss of clonogenicity and diminished tissue regenerative ability.

  4. for the first time, PKD3 is implicated in the transcription activation of latent HIV-1 provirus, and our results revealed a molecular mechanism of prostratin-induced HIV-1 transcription via PKCepsilon (show PRKCE Antibodies)/PKD3/NF-kappaB (show NFKB1 Antibodies) signaling pathway.

  5. Activation of PKD2 (show PKD2 Antibodies) and further increase of PKD3 activity leads to additional phosphorylation and inhibition of endogenous phosphatase slingshot 1L (show SSH1 Antibodies).

  6. PKD3 in TNBC cells provides a molecular connection between the Golgi and endolysosomal compartments to enhance proliferative mTORC1-S6K1 (show RPS6KB1 Antibodies) signaling.

  7. PKD3 negatively regulates human airway epithelial barrier formation and integrity through down-regulation of claudin-1 (show CLDN7 Antibodies), which is a key component of tight junctions.

  8. PKD3 may contribute to the malignant progression of prostate cancer cells through negative regulation of MMP-7 (show MMP7 Antibodies) expression.

  9. PKD3 contributes to the proliferation and malignant growth of androgen-dependent prostate cancer cells in part by upregulating PSA (show PLAG1 Antibodies) expression.

  10. these data suggest that PKD2 (show PKD2 Antibodies) and PKD3 coordinate to promote prostate cancer cell invasion through p65 NF-kappaB (show NFkBP65 Antibodies)- and HDAC1 (show HDAC1 Antibodies)-mediated expression and activation of uPA (show PRAP1 Antibodies).

Mouse (Murine) Protein Kinase D3 (PRKD3) interaction partners

  1. Erythropoietin (show EPO Antibodies) regulates GATA1 (show GATA1 Antibodies) through protein kinase D (show PRKD1 Antibodies) activation, promoting histone deacetylase 5 (show HDAC5 Antibodies) dissociation from GATA1 (show GATA1 Antibodies), and subsequent GATA1 (show GATA1 Antibodies) acetylation.

  2. These data validate PKD3 as a promising therapeutic target in prostate cancer and shed light on the role of secreted tumor-promoting factors in prostate cancer progression.

  3. PKCnu is an important component of signaling pathways downstream from novel PKC enzymes after B-cell receptor engagement

  4. the catalytic activity of PKD3 may regulate its nuclear import through autophosphorylation and/or interaction with another protein

  5. PKD3 is increasingly expressed in neuronal as well as in the supporting connective tissue and in skeletal muscles

  6. reveal a novel distinction between the exocrine and endocrine cells of the pancreas and further identify PKD3 as a signaling molecule that promotes hormone-stimulated amylase (show AMY Antibodies) secretion

Protein Kinase D3 (PRKD3) Antigen Profile

Protein Summary

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members.

Gene names and symbols associated with PRKD3

  • protein kinase D3 (PRKD3) antibody
  • protein kinase D3 (prkd3) antibody
  • polycystic kidney disease 3 (autosomal dominant) (PKD3) antibody
  • protein kinase D3 (Prkd3) antibody
  • 4930557O20Rik antibody
  • 5730497N19Rik antibody
  • EPK2 antibody
  • nPKC-NU antibody
  • PKC-NU antibody
  • Pkcnu antibody
  • PKD3 antibody
  • Prkcn antibody
  • PRKD3 antibody

Protein level used designations for PRKD3

protein kinase D3 , serine/threonine-protein kinase D3-like , protein kinase C nu type , protein kinase C, nu , protein kinase EPK2 , protein-serine/threonine kinase , serine/threonine-protein kinase D3 , nPKC-nu

GENE ID SPECIES
459158 Pan troglodytes
709647 Macaca mulatta
100397078 Callithrix jacchus
100438207 Pongo abelii
100466224 Ailuropoda melanoleuca
100077901 Ornithorhynchus anatinus
100563064 Anolis carolinensis
100581692 Nomascus leucogenys
5312 Homo sapiens
23683 Homo sapiens
75292 Mus musculus
313834 Rattus norvegicus
483036 Canis lupus familiaris
100523181 Sus scrofa
100712662 Cavia porcellus
538447 Bos taurus
421478 Gallus gallus
Selected quality suppliers for anti-Protein Kinase D3 (PRKD3) Antibodies
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