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anti-RAB8A, Member RAS Oncogene Family (RAB8A) Antibodies

The protein encoded by RAB8A is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. Additionally we are shipping RAB8A Kits (14) and RAB8A Proteins (14) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RAB8A 4218 P61006
RAB8A 17274 P55258
RAB8A 117103 P35280
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Top anti-RAB8A Antibodies at antibodies-online.com

Showing 10 out of 82 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-RAB8A Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: 721_B cell lysate Sample Type: 1. Human Cervical Cancer Cell Lysate (15ug)2. Monkey Fibroblast Cell Lysate (15ug)3. Human Cervical Cancer Cell transfected with mouse Rab8A-GFP  (15ug)Primary Dilution: 1:1000Secondary Antibody: goat anti-RabbitSecondary Dilution: 1:40,000Image Submitted by:  Dr. Jakob Szwedo, Dr. Lupashin's LabUniversity of Arkansas for Medical Sciences. 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, WB ABIN238664 (0.1µg/ml) staining of Human Brain (Cerebellum) lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Cow Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Dog Mouse Un-conjugated IF, IP, IHC, WB Western blot analysis of Rab8 on a Jurkat cell lysate. Lane 1: 1:1000, lane 2: 1:2000, lane 3: 1:4000 dilution of the anti- Rab8 antibody. Immunofluorescence staining of WI-38 cells (human lung fibroblasts, ATCC CCL-75). 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB RAB8A Antibody (ABIN1881723) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. RAB8A Antibody (ABIN1881723) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-RAB8A antibody, IHC(P) IHC(P): Human Intestinal Cancer Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human esophageal carcinoma labeled with Anti-RAB8 Polyclonal Antibody, Unconjugated (ABIN715316) at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Dog Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details

RAB8A Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-RAB8A Antibodies

  1. Dog (Canine) Monoclonal RAB8A Primary Antibody for IF, IP - ABIN968210 : Bahadoran, Aberdam, Mantoux, Buscà, Bille, Yalman, de Saint-Basile, Casaroli-Marano, Ortonne, Ballotti: Rab27a: A key to melanosome transport in human melanocytes. in The Journal of cell biology 2001 (PubMed)
    Show all 5 references for ABIN968210

  2. Human Polyclonal RAB8A Primary Antibody for FACS, IHC (p) - ABIN1881723 : Kato, Sekine, Oh, Kim, Umezawa, Abe, Yokoyama-Kobayashi, Aoki: Construction of a human full-length cDNA bank. in Gene 1995 (PubMed)
    Show all 2 references for ABIN1881723

  3. Cow (Bovine) Polyclonal RAB8A Primary Antibody for ELISA, WB - ABIN374945 : Yoshimura, Egerer, Fuchs, Haas, Barr: Functional dissection of Rab GTPases involved in primary cilium formation. in The Journal of cell biology 2007 (PubMed)

  4. Chicken Polyclonal RAB8A Primary Antibody for WB - ABIN2792290 : Roland, Kenworthy, Peranen, Caplan, Goldenring: Myosin Vb interacts with Rab8a on a tubular network containing EHD1 and EHD3. in Molecular biology of the cell 2007 (PubMed)

More Antibodies against RAB8A Interaction Partners

Human RAB8A, Member RAS Oncogene Family (RAB8A) interaction partners

  1. Data demonstrate that EHBP1L1 links Rab8 and the Bin1 (show BIN1 Antibodies)-dynamin (show DNM1 Antibodies) complex, which generates membrane curvature and excises the vesicle at the endocytic recycling compartment for apical transport.

  2. Further exploration of the NINL (show NINL Antibodies)-associated interactome identifies MICAL3, a protein known to interact with Rab8 and to play an important role in vesicle docking and fusion.

  3. The small GTPase (show RACGAP1 Antibodies) Rab8 interacts with VAMP-3 (show VAMP3 Antibodies) to regulate the delivery of recycling T-cell receptors to the immune synapse.

  4. the role of Rabin8 (show RAB3IP Antibodies) (a mammalian ortholog of Sec2p) with Rab8-nucleotide-exchange factor activity in autophagy in mammalian cells, was examined.

  5. DLC3 (show STARD8 Antibodies) is recruited to Rab8-positive membrane tubules and is required for the integrity of the Rab8 and Golgi compartments.

  6. Rab8A GTPase (show RACGAP1 Antibodies) Ser (show SIGLEC1 Antibodies)(111) phosphorylation is not directly regulated by PINK1 (show PINK1 Antibodies) in vitro and demonstrate in cells the time course of Ser (show SIGLEC1 Antibodies)(111) phosphorylation of Rab8A, 8B and 13 is markedly delayed compared to phosphorylation of Parkin (show PARK2 Antibodies) at Ser (show SIGLEC1 Antibodies)(65).

  7. Intercellular transfer of transferrin receptor by a contact-, Rab8-dependent mechanism involving tunneling nanotubes.

  8. High expression of RAB8A is associated with endometrial cancer.

  9. Study established a direct interaction between alpha-synclein and Rab8a and provided unique insights into the molecular mechanisms of alpha-synclein toxicity

  10. Rab8a and Drebrin E (show DBN1 Antibodies) act as key proteins in the regulation of apical trafficking in intestinal epithelial cells.

Zebrafish RAB8A, Member RAS Oncogene Family (RAB8A) interaction partners

  1. Cc2d2a (show CC2D2A Antibodies), localized at the photoreceptor connecting cilium/transition zone, facilitates protein transport through a role in Rab8-dependent vesicle trafficking and fusion.

  2. Data show that elipsa (show TRAF3IP1 Antibodies) encodes a coiled-coil polypeptide that localizes to cilia, and that it interacts genetically with Rabaptin5, a well-studied regulator of endocytosis, which in turn interacts with Rab8, a small GTPase (show RACGAP1 Antibodies), known to localize to cilia.

Mouse (Murine) RAB8A, Member RAS Oncogene Family (RAB8A) interaction partners

  1. Data demonstrate that EHBP1L1 links Rab8 and the Bin1 (show BIN1 Antibodies)-dynamin (show DNM1 Antibodies) complex, which generates membrane curvature and excises the vesicle at the endocytic recycling compartment for apical transport.

  2. The small GTPase (show RACGAP1 Antibodies) Rab8 interacts with VAMP-3 (show VAMP3 Antibodies) to regulate the delivery of recycling T-cell receptors to the immune synapse.

  3. Rab8a thus controls Wnt (show WNT2 Antibodies) delivery in producing cells and is crucial for Paneth cell maturation.

  4. Rab8a acts as an activator of Fsp27 (show CIDEC Antibodies)-mediated LD fusion and growth.

  5. Simultaneous loss of Rab8a and Rab8b (show RAB8B Antibodies) has little effect on ciliogenesis, whereas additional loss of Rab10 (show RAB10 Antibodies) greatly affects ciliogenesis.

  6. acidosis-induced NBCe1 (show SLC4A4 Antibodies)-A, but not NBCe1 (show SLC4A4 Antibodies)-B/C, trafficking is mediated by Rab8a.

  7. AS160 (show TBC1D4 Antibodies) and Rab8a regulate membrane recruitment of CD36 (show CD36 Antibodies).

  8. Cdc42 (show CDC42 Antibodies) and Rab8a are critical for intestinal stem cell division, survival, and differentiation in mice

  9. Rab8a colocalizes with IL-1b (show IL1B Antibodies) and LC3 (show MAP1LC3A Antibodies) and controls IL-1b (show IL1B Antibodies) secretion

  10. Rab13 (show RAB13 Antibodies) and Rab8A are Rab (show HRB Antibodies)-GTPases activated by insulin (show INS Antibodies) and downstream of AS160 (show TBC1D4 Antibodies) they regulate traffic of GLUT4 (show SLC2A4 Antibodies) vesicles.

RAB8A Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1.

Gene names and symbols associated with RAB8A

  • rab8A protein (rab8A) antibody
  • Rab GTPase (rab8A) antibody
  • RAB8A, member RAS oncogene family (RAB8A) antibody
  • RAB8A, member RAS oncogene family (rab8a) antibody
  • RAB8A, member RAS oncogene family (Rab8a) antibody
  • AA409338 antibody
  • c-mel antibody
  • DDBDRAFT_0206521 antibody
  • DDBDRAFT_0214885 antibody
  • DDB_0206521 antibody
  • DDB_0214885 antibody
  • HSH2D antibody
  • Mel antibody
  • Rab8 antibody
  • rab8A antibody
  • zgc:162699 antibody

Protein level used designations for RAB8A

rab8A protein , hematopoietic SH2 domain containing , ras-related protein Rab-8A , RAB8A, member RAS oncogene family , member RAS oncogene family , Ras-related protein Rab-8A , mel transforming oncogene (RAB8 homolog) , mel transforming oncogene (derived from cell line NK14) , mel transforming oncogene (derived from cell line NK14)- RAB8 homolog , oncogene c-mel , ras-associated protein RAB8 , RAB8, member RAS oncogene family , cell line NK14 derived transforming oncogene

GENE ID SPECIES
553899 Lotus japonicus
8622514 Dictyostelium discoideum AX4
468760 Pan troglodytes
100125217 Xenopus (Silurana) tropicalis
100380328 Salmo salar
4218 Homo sapiens
403773 Canis lupus familiaris
100125881 Bos taurus
571897 Danio rerio
100037230 Xenopus laevis
428352 Gallus gallus
17274 Mus musculus
117103 Rattus norvegicus
100174026 Pongo abelii
101092668 Felis catus
100511006 Sus scrofa
100302063 Ovis aries
100734132 Cavia porcellus
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