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RAB8A antibody (C-Term)

RAB8A Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3042554
  • Target See all RAB8A Antibodies
    RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))
    Binding Specificity
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 170-183, C-Term
    Reactivity
    • 37
    • 10
    • 9
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 21
    • 11
    • 4
    Rabbit
    Clonality
    • 25
    • 12
    Polyclonal
    Conjugate
    • 23
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This RAB8A antibody is un-conjugated
    Application
    • 21
    • 11
    • 6
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purpose
    Rabbit IgG polyclonal antibody for Ras-related protein Rab-8A(RAB8A) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Sequence
    KAKMDKKLEG NSPQ
    Cross-Reactivity (Details)
    No cross reactivity with other proteins.
    Characteristics
    Rabbit IgG polyclonal antibody for Ras-related protein Rab-8A(RAB8A) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: RAB8A, member RAS oncogene family
    Protein Name: Ras-related protein Rab-8A
    Purification
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the C-terminus of human RAB8A(170-183aa KAKMDKKLEGNSPQ), identical to the related mouse and rat sequences.
    Isotype
    IgG
    Top Product
    Discover our top product RAB8A Primary Antibody
  • Application Notes
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Comment

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Preservative
    Thimerosal (Merthiolate), Sodium azide
    Precaution of Use
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Target
    RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))
    Alternative Name
    RAB8A (RAB8A Products)
    Synonyms
    rab8A antibody, DDBDRAFT_0206521 antibody, DDBDRAFT_0214885 antibody, DDB_0206521 antibody, DDB_0214885 antibody, HSH2D antibody, mel antibody, rab8 antibody, c-mel antibody, MEL antibody, RAB8 antibody, zgc:162699 antibody, AA409338 antibody, Mel antibody, Rab8 antibody, rab8A protein antibody, Rab GTPase antibody, RAB8A, member RAS oncogene family antibody, RAB8A, member RAS oncogene family S homeolog antibody, rab8A antibody, RAB8A antibody, rab8a antibody, rab8a.S antibody, Rab8a antibody
    Background
    Ras-related protein Rab-8A is a protein that in humans is encoded by the RAB8A gene. It is mapped to 19p13.12. The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. RAB8A regulates cilia assembly by targeting and promoting fusion of vesicles near the ciliary membrane. This gene requires CEP290 for centrosome localization and that CEP290 regulates entry of RAB8A into the cilium during assembly of this organelle. RAB8A has been shown to interact with Optineurin and MAP4K2.

    Synonyms: AA409338 antibody|MEL antibody|Mel transforming oncogene(derived from cell line NK14) RAB8 homolog antibody|Mel transforming oncogene(derived from cell line NK14) antibody|Mel transforming oncogene(RAB8 homolog) antibody|Mel transforming oncogene antibody|MGC124948 antibody|Oncogene c mel antibody|Oncogene c-mel antibody|RAB8 antibody|RAB8A antibody|RAB8A member RAS oncogene family antibody|Ras associated protein RAB8 antibody|Ras related protein Rab 8A antibody|Ras-related protein Rab-8A antibody
    UniProt
    P61006
    Pathways
    M Phase, Regulation of long-term Neuronal Synaptic Plasticity, SARS-CoV-2 Protein Interactome
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