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anti-RAN Binding Protein 1 (RANBP1) Antibodies

Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. Additionally we are shipping RANBP1 Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RANBP1 5902 P43487
RANBP1 19385 P34022
RANBP1 360739  
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Top anti-RANBP1 Antibodies at antibodies-online.com

Showing 10 out of 47 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-RANBP1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: 721_B cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IF, WB Western blot analysis of RanBP1 on HepG2 lysate. Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of RanBP1. Immunofluorescence staining of Human Fibroblast cells. 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Goat Un-conjugated ELISA, WB ABIN185257staining (0.1µg/ml) of HepG2 lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. ABIN185257 (0.05 µg/mL) staining of HELA lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Goat Un-conjugated EIA, IHC (p), WB 20 μg Log in to see 6 to 8 Days
$203.50
Details
Human Rabbit Un-conjugated ICC, IF, WB ICC/IF Image Ran BP1 antibody [N1C3] detects Ran BP1 protein at cytoplasm by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: Ran BP1 protein stained by Ran BP1 antibody [N1C3] , diluted at 1:500. Red: alpha Tubulin, a cytoskeleton marker, stained by alpha Tubulin antibody [B-5-1-2] , diluted at 1:10000. Blue: Hoechst 33342 staining. WB Image Sample (50 ug of whole cell lysate) A: Mouse brain 12% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Goat Un-conjugated IHC (p), ELISA, WB Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$595.83
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human rectal carcinoma labeled with Anti-RanBP1 Polyclonal Antibody, Unconjugated (ABIN1387616) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Cow Rabbit Un-conjugated IF, WB AP19035PU-N Ran BP1 antibody staining of Paraformaldehyde-fixed HeLa by Immunofluorescence at 1/200 dilution. AP19035PU-N Ran BP1 antibody staining of HeLaS3 (A) whole cell lysate (30 µg) at 1/1000 dilution, 12% SDS PAGE. 0.1 mL Log in to see 6 to 8 Days
$401.50
Details
Cow Rabbit Un-conjugated WB Western blot analysis of RANBP1 expression in HeLa (A), mouse brain (B), rat brain (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details

RANBP1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-RANBP1 Antibodies

  1. Human Monoclonal RANBP1 Primary Antibody for IF, WB - ABIN968158 : Bischoff, Krebber, Smirnova, Dong, Ponstingl: Co-activation of RanGTPase and inhibition of GTP dissociation by Ran-GTP binding protein RanBP1. in The EMBO journal 1995 (PubMed)
    Show all 3 references for ABIN968158

  2. Cow (Bovine) Polyclonal RANBP1 Primary Antibody for WB - ABIN2773873 : Tedeschi, Ciciarello, Mangiacasale, Roscioli, Rensen, Lavia: RANBP1 localizes a subset of mitotic regulatory factors on spindle microtubules and regulates chromosome segregation in human cells. in Journal of cell science 2007 (PubMed)

More Antibodies against RANBP1 Interaction Partners

Xenopus laevis RAN Binding Protein 1 (RANBP1) interaction partners

  1. findings reveal an important mitotic role for RanBP1, controlling the spatial distribution and magnitude of mitotic Ran-GTP (show AK3 Antibodies) production and thereby ensuring accurate execution of Ran-dependent mitotic events

Human RAN Binding Protein 1 (RANBP1) interaction partners

  1. Sgk1 (show SGK1 Antibodies)-dependent regulation of RANBP1 has functional consequences on both mitotic microtubule activity and taxol sensitivity of cancer cells.

  2. in vitro and in vivo phosphorylation of RanBP1 by Plk1 (show PLK1 Antibodies) as well as the importance of phosphorylation of RanBP1 in the interaction between Plk1 (show PLK1 Antibodies) and Ran during early mitosis, is demonstrated.

  3. RANBP1 on 22q11.21 locus might be causally related to the smooth pursuit eye movement abnormality rather than the development of schizophrenia.

  4. Downregulation of the Ran GTPase (show RAN Antibodies) effector RanBP1 is required for nuclear reorganisation.

  5. structure of the Ran-RanBP1-RanGAP complex

  6. Phosphorylated wild type RanGAP1 (show RANGAP1 Antibodies), but not a mutant harboring a mutation at the phosphorylation site 358S, efficiently formed a stable ternary complex with Ran and RanBP1 in vivo, suggesting that the 358S phosphorylation of RanGAP1 (show RANGAP1 Antibodies) affects the Ran system.

  7. These data indicate that RANBP1 activity is required for the proper localization of specific factors that regulate microtubule function; loss of this activity contributes to the generation of aneuploidy in a microtubule-dependent manner.

  8. RanBP1-interfered cells show an increased apoptotic response to taxol compared to their counterpart with normal or high RanBP1 levels, and this response is caspase-3 (show CASP3 Antibodies) dependent.

  9. Generation of Ran-GTP (show AK3 Antibodies) from Ran-GDP by importin-beta (show KPNB1 Antibodies) is activated by Ran-binding protein-1 (RanBP1) that forms a trimeric complex with Ran-GDP and importin-beta (show KPNB1 Antibodies).

Mouse (Murine) RAN Binding Protein 1 (RANBP1) interaction partners

  1. Ranbp1 emerges as a microcephaly gene within the 22q11.2 deleted region that may contribute to altered cortical precursor proliferation and neurogenesis associated with broader 22q11.2 deletion.

  2. Data suggest Ran activation by RanBP1 in macrophages promotes Legionella phagosome formation and phagocytosis; LegG1 functions as bacterial Ran activator, localizes to phagosomes, and promotes microtubule stabilization, phagocytosis, and replication.

  3. The dramatic decrease in "RanBP" activity impairs germ cell viability and affects spermatogenesis decisively in RanBP1-knockout mice.

  4. Downregulation of the Ran GTPase (show RAN Antibodies) effector RanBP1 is required for nuclear reorganisation.

  5. expressed in the frontonasal processes, branchial arches, aortic arches, and limb buds. At these sites, RanBP1 apparently coincides with neural crest-derived mesenchymal cells. In addition, RanBP1 is expressed in the forebrain

  6. RanBP1 interferes with crucial factor(s) that control structural and dynamic features of centrosomes during mitosis

  7. Tax (show CNTN2 Antibodies) directly binds Ran and Ran-binding protein-1, locates to centrosomes/spindle poles, and causes supernumerary centrosomes

RANBP1 Antigen Profile

Protein Summary

Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.

Gene names and symbols associated with RANBP1

  • RAN binding protein 1 (ranbp1) antibody
  • Ran binding protein 1 (LOC397932) antibody
  • ran binding protein 1 (PVX_090070) antibody
  • RAN binding protein 1 (GL50803_16969) antibody
  • RAN binding protein 1 (LOC100343953) antibody
  • RAN binding protein 1 (RANBP1) antibody
  • RAN binding protein 1 (Ranbp1) antibody
  • hm:zeh1094 antibody
  • Htf9a antibody
  • MGC64314 antibody
  • wu:fa96a09 antibody
  • wu:fj39g07 antibody
  • zeh1094 antibody
  • zgc:85649 antibody

Protein level used designations for RANBP1

RAN binding protein 1 , Ran binding protein 1 , ran binding protein 1 , ran-specific GTPase-activating protein , HpaII tiny fragments locus 9A , Htf9-a/RanBP1 , hpaII tiny fragments locus 9a protein , ran-binding protein 1

GENE ID SPECIES
379454 Xenopus laevis
397932 Xenopus laevis
5474397 Plasmodium vivax Sal-1
5701654 Giardia lamblia ATCC 50803
100343953 Oryctolagus cuniculus
337046 Danio rerio
5902 Homo sapiens
19385 Mus musculus
360739 Rattus norvegicus
533251 Bos taurus
416787 Gallus gallus
477563 Canis lupus familiaris
100151896 Sus scrofa
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