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The protein encoded by RNF138 contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions. Additionally we are shipping Ring Finger Protein 138 Proteins (9) and many more products for this protein.
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Cow (Bovine) Polyclonal RNF138 Primary Antibody for WB - ABIN2777704
Yamada, Ohnishi, Ohkawara, Iemura, Satoh, Hyodo-Miura, Kawachi, Natsume, Shibuya: NARF, an nemo-like kinase (NLK)-associated ring finger protein regulates the ubiquitylation and degradation of T cell factor/lymphoid enhancer factor (TCF/LEF). in The Journal of biological chemistry 2006
Data show that ubiquitin E3 ligase RNF138 regulates Ku80 (show XRCC5 Antibodies) antigen ubiquitylation in response to DNA damage.
Data show that ubiquitin E2 enzymes UBE2D1 (show UBE2D1 Antibodies)/2/3 and E3 ligase RNF138 accumulate at DNA-damage sites and act at early resection stages by promoting CtIP (show RBBP8 Antibodies) protein ubiquitylation and accrual.
The RNF138 gene is highly expressed in glioma tissue and glioma cell lines and plays an important role in glioma cell proliferation, apoptosis, and cell cycle.
NARF functions as a novel ubiquitin-ligase to regulate ubiquitylation and degradation of T cell factor/lymphoid enhancer factor
The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
E3 ubiquitin-protein ligase RNF138
, NLK-associated RING finger protein
, Nemo-like kinase-associated RING finger protein
, nemo-like kinase associated ring finger protein
, nemo-like kinase-associated RING finger protein