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anti-Ring Finger Protein 139 (RNF139) Antibodies

The protein encoded by RNF139 is a multi-membrane spanning protein containing a RING-H2 finger. Additionally we are shipping Ring Finger Protein 139 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RNF139 11236 Q8WU17
RNF139 75841 Q7TMV1
RNF139 315000  
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Top anti-Ring Finger Protein 139 Antibodies at antibodies-online.com

Showing 10 out of 50 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-RNF139 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Dog Goat Un-conjugated EIA, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Mouse Un-conjugated WB RNF139 monoclonal antibody (M01), clone 3D10 Western Blot analysis of RNF139 expression in HepG2 on formalin-fixed paraffin-embedded human tonsil (antibody concentration 3 µg/mL). 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to RNF139 on formalin-fixed paraffin-embedded human tonsil. [antibody concentration 3 ug/ml] RNF139 monoclonal antibody (M01), clone 3D10 Western Blot analysis of RNF139 expression in HepG2 . 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Goat Un-conjugated IHC, ELISA, WB (1µg/ml) staining of Human Skeletal Muscle lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated IHC (p), ELISA, WB 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details

RNF139 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-Ring Finger Protein 139 Antibodies

  1. Human Monoclonal RNF139 Primary Antibody for WB - ABIN393698 : Lee, Brauweiler, Rudolph, Hooper, Drabkin, Gemmill: The TRC8 ubiquitin ligase is sterol regulated and interacts with lipid and protein biosynthetic pathways. in Molecular cancer research : MCR 2010 (PubMed)
    Show all 5 references for ABIN393698

  2. Human Polyclonal RNF139 Primary Antibody for ELISA, WB - ABIN564886 : Brauweiler, Lorick, Lee, Tsai, Chan, Weissman, Drabkin, Gemmill: RING-dependent tumor suppression and G2/M arrest induced by the TRC8 hereditary kidney cancer gene. in Oncogene 2007 (PubMed)
    Show all 4 references for ABIN564886

  3. Dog (Canine) Polyclonal RNF139 Primary Antibody for EIA, IHC (p) - ABIN375132 : Gemmill, West, Boldog, Tanaka, Robinson, Smith, Li, Drabkin: The hereditary renal cell carcinoma 3;8 translocation fuses FHIT to a patched-related gene, TRC8. in Proceedings of the National Academy of Sciences of the United States of America 1998 (PubMed)
    Show all 2 references for ABIN375132

  4. Cow (Bovine) Polyclonal RNF139 Primary Antibody for WB - ABIN2774685 : Poland, Azim, Folsom, Goldfarb, Naeem, Korch, Drabkin, Gemmill, Plon: A constitutional balanced t(3;8)(p14;q24.1) translocation results in disruption of the TRC8 gene and predisposition to clear cell renal cell carcinoma. in Genes, chromosomes & cancer 2007 (PubMed)

  5. Human Monoclonal RNF139 Primary Antibody for IHC (p), ELISA - ABIN564887 : Adams, Simms, Abdelhamed, Dawe, Szymanska, Logan, Wheway, Pitt, Gull, Knowles, Blair, Cross, Sayer, Johnson: A meckelin-filamin A interaction mediates ciliogenesis. in Human molecular genetics 2012 (PubMed)

More Antibodies against Ring Finger Protein 139 Interaction Partners

Human Ring Finger Protein 139 (RNF139) interaction partners

  1. TRC8 and TMEM129 are endoplasmic reticulum-associated degradation ubiquitin E3 ligases for viral and cellular targeting of MHC class I. (Review)

  2. TRC8 suppresses tumorigenesis through targeting heme oxygenase-1 (show HMOX1 Antibodies) for ubiquitination and degradation.

  3. TRC8 function may provide a regulatory link between the lipid and protein biosynthetic pathways.

  4. TRC8 modulation of sterol response element binding protein activity comprises a novel regulatory link between growth control and the cholesterol/lipid homeostasis pathway.

  5. The presence of diploid and tetraploid tumor cells with and without TRC8 deletions on the nontranslocated chromosome suggest that loss of the remaining normal allele of TRC8 may contribute to tumor development at later stages.

  6. TRC8 is a novel sterol-sensing endoplasmic reticulum membrane protein (show SLC39A6 Antibodies) that hinders SREBP-2 (show SREBF2 Antibodies) processing through interaction with SREBP-2 (show SREBF2 Antibodies) and SCAP (show SH2D2A Antibodies), regulating its own turnover rate by means of its E3 ubiquitin ligase (show MUL1 Antibodies) activity

  7. Data show that the TRC8 E3 ligase is required for MHC I dislocation from the ER and identify a new complex associated with mammalian ERAD.

Ring Finger Protein 139 (RNF139) Antigen Profile

Protein Summary

The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.

Gene names and symbols associated with RNF139

  • ring finger protein 139 (RNF139) antibody
  • ring finger protein 139 (Rnf139) antibody
  • 4930555P18Rik antibody
  • DKFZp469C1333 antibody
  • HRCA1 antibody
  • RCA1 antibody
  • RNF139 antibody
  • TRC8 antibody

Protein level used designations for RNF139

ring finger protein 139 , E3 ubiquitin-protein ligase RNF139 , multiple membrane spanning receptor TRC8 , patched related protein translocated in renal cancer , translocation in renal carcinoma on chromosome 8 protein , RING finger protein 139

GENE ID SPECIES
100067392 Equus caballus
100172342 Pongo abelii
11236 Homo sapiens
609422 Canis lupus familiaris
788471 Bos taurus
75841 Mus musculus
315000 Rattus norvegicus
420338 Gallus gallus
100156613 Sus scrofa
100447707 Pongo abelii
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