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anti-Ring Finger Protein 2 (RNF2) Antibodies

Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. Additionally we are shipping RNF2 Proteins (7) and RNF2 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RNF2 6045 Q99496
RNF2 19821 Q9CQJ4
RNF2 304850 Q4KLY4
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Top anti-RNF2 Antibodies at antibodies-online.com

Showing 10 out of 64 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-RNF2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:3... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated IHC, WB WB Suggested Anti-RNF2 Antibody Titration: 1.25ug/mlELISA Titer: 1:312... 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Mouse Un-conjugated WB Western Blot analysis of RNF2 expression in transfected 293T cell line... 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Hamster Mouse Un-conjugated IP, WB 0.1 mg Log in to see 6 to 8 Days
$456.50
Details
Human Goat Un-conjugated ELISA, WB ABIN184925 staining (0.5 µg/ml) of K562 lysate (RIPA buffer, 35µg tota... 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Mouse Un-conjugated WB RNF2 monoclonal antibody (M14), clone 2B4. Western Blot analysis of RN... 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Chicken Goat Un-conjugated EIA, IF, IHC (p), WB   0.1 mg Log in to see 6 to 8 Days
$500.50
Details
Cow Goat Un-conjugated EIA, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Mouse Un-conjugated ChIPSeq, ChIP, ICC, IF, IP, WB Ring1B antibody (mAb) tested by ChIP-chip. ChIP was performed using th... 100 μg Log in to see 1 to 2 Days
$478.33
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of RING2/RING1B/RNF2 expression in rat brain ext... RING2/RING1B/RNF2 was detected in paraffin-embedded sections of human ... 100 μg Log in to see 4 to 6 Days
$200.00
Details

RNF2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
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Top referenced anti-RNF2 Antibodies

  1. Human Monoclonal RNF2 Primary Antibody for WB - ABIN393566 : Zaaroor-Regev, de Bie, Scheffner, Noy, Shemer, Heled, Stein, Pikarsky, Ciechanover: Regulation of the polycomb protein Ring1B by self-ubiquitination or by E6-AP may have implications to the pathogenesis of Angelman syndrome. in Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)
    Show all 5 references for ABIN393566

  2. Human Monoclonal RNF2 Primary Antibody for WB - ABIN393851 : Suzuki, Iwamura, Shinoda, Tumes, Kimura, Hosokawa, Endo, Horiuchi, Tokoyoda, Koseki, Yamashita, Nakayama: Polycomb group gene product Ring1B regulates Th2-driven airway inflammation through the inhibition of Bim-mediated apoptosis of effector Th2 cells in the lung. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)
    Show all 5 references for ABIN393851

  3. Chicken Polyclonal RNF2 Primary Antibody for EIA, IF - ABIN117940 : Tuckfield, Clouston, Wilanowski, Zhao, Cunningham, Jane: Binding of the RING polycomb proteins to specific target genes in complex with the grainyhead-like family of developmental transcription factors. in Molecular and cellular biology 2002 (PubMed)
    Show all 4 references for ABIN117940

  4. Human Monoclonal RNF2 Primary Antibody for ChIPSeq, ChIP - ABIN2668629 : Basu, Wilkinson, Colavita, Fennelly, Atchison: YY1 DNA binding and interaction with YAF2 is essential for Polycomb recruitment. in Nucleic acids research 2014 (PubMed)
    Show all 3 references for ABIN2668629

  5. Hamster Monoclonal RNF2 Primary Antibody for IP, WB - ABIN1449179 : Atsuta, Fujimura, Moriya, Vidal, Akasaka, Koseki: Production of monoclonal antibodies against mammalian Ring1B proteins. in Hybridoma 2001 (PubMed)
    Show all 2 references for ABIN1449179

  6. Chicken Polyclonal RNF2 Primary Antibody for IHC, WB - ABIN2775705 : Voncken, Roelen, Roefs, de Vries, Verhoeven, Marino, Deschamps, van Lohuizen: Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition. in Proceedings of the National Academy of Sciences of the United States of America 2003 (PubMed)

More Antibodies against RNF2 Interaction Partners

Zebrafish Ring Finger Protein 2 (RNF2) interaction partners

  1. The polycomb group protein (show CBX4 Antibodies) ring1b/rnf2 is specifically required for craniofacial development.

  2. These results reveal that, in the absence of functional Ring1b, fin bud cells fail to execute the pectoral fin developmental program.

Human Ring Finger Protein 2 (RNF2) interaction partners

  1. O-GlcNAc (show OGT Antibodies) modifies and regulates an essential epigenetic tool, RING1B, which may contribute to human embryonic stem cells pluripotency maintenance and differentiation.

  2. The enzymatic activity of BMI1 (show BMI1 Antibodies) and RING1B were evaluated and compared.

  3. Bmi1 (show BMI1 Antibodies) and possibly RNF2 may be attractive biomarkers of gemcitabine resistance in the context of RRM1 (show RRM1 Antibodies) expression.

  4. combinatorial silencing along with Ezh2 (show EZH2 Antibodies) depleted epigenetically modified H2- and H3-histones and inhibited pancreatic cancer cell growth in vitro and in vivo (xenograft model)

  5. BAP1 deficiency causes increased expression of FoxK2 (show FOXK2 Antibodies) target genes in a Ring1B-Bmi1 (show BMI1 Antibodies)-dependent manner

  6. Authors describe a critical role for the polycomb group protein Ring1b in nonhomologous end-joining (NHEJ)-mediated end-to-end chromosome fusions.

  7. we identify p63 (show RPE65 Antibodies) as a target of Ring1B to regulate Fak (show PTK2 Antibodies) expression in breast cancer epithelial cells

  8. Ring1B and the SNAG-associated chromatin modifier EZH2 formed distinct protein complexes with Snail and that EZH2 was required for Snail-Ring1A/B recruitment to the target promoter.

  9. The acidic patch functions within the nucleosome as nucleosomes containing a mutated acidic patch exhibit defective H2A/H2AXub by RNF168 (show RNF168 Antibodies) and RING1B/BMI1 (show BMI1 Antibodies) in vitro

  10. Data indicate that RING finger protein 2 (RNF2) knockdown can increase the sensitivity of U87 cells to X ray radiation.

Mouse (Murine) Ring Finger Protein 2 (RNF2) interaction partners

  1. the ability of RING1B, a core component of PRC1 (show PRC1 Antibodies), to ubiquitinate histone H2A is dispensable for early mouse embryonic development and much of the gene repression activity of PRC1 (show PRC1 Antibodies)

  2. RNF2 associates with AMBRA1 (show AMBRA1 Antibodies) to act as an E3 ligase to ubiquitinate AMBRA1 (show AMBRA1 Antibodies) via K48 linkage.

  3. The polycomb (show CBX2 Antibodies) component Ring1B regulates the timed termination of Fezf2 (show FEZF2 Antibodies) expression and thus subcerebral projection neuron production during mouse neocortical development.

  4. Expansion of hepatic stem/progenitor cells requires Ring1B-mediated epigenetic silencing of Cdkn1a (show CDKN1A Antibodies) and Cdkn2a (show CDKN2A Antibodies), demonstrating that Ring1B simultaneously regulates multiple CDKIs in tissue stem/progenitor cells.

  5. Af9 (show MLLT3 Antibodies) mediates site-selective physical and functional recruitment of Rnf2 to the alpha-ENaC (show SCNN1A Antibodies) promoter to constrain basal alpha-ENaC (show SCNN1A Antibodies) transcription in collecting duct cells.

  6. Ring1b mediates Meis2 (show MEIS2 Antibodies) promoter and midbrain-specific enhancer association.

  7. Aurora B (show AURKC Antibodies) and Ring1B co-occupy active promoters in resting lymphocytes.

  8. Fbxl10 (show KDM2B Antibodies) has a key role in regulating Ring1B recruitment to its target genes and H2AK119 ubiquitylation in embryonic stem cells.

  9. identification of gene-dosage-dependent roles in primordial germ cell development for Ring1 (show RING1 Antibodies) and Rnf2, two central components of the Polycomb (show CBX2 Antibodies) repressive complex 1 (PRC1 (show PRC1 Antibodies))

  10. Ring1b inactivation in differentiated islet beta cells (Ring1b(betaKO)) did not cause derepression, even after multiple rounds of cell division, suggesting a role for Ring1b in the establishment but not the maintenance of repression

RNF2 Antigen Profile

Protein Summary

Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.

Gene names and symbols associated with RNF2

  • ring finger protein 2 (rnf2) antibody
  • ring finger protein 2 (RNF2) antibody
  • ring finger protein 2 (Rnf2) antibody
  • AI326319 antibody
  • AI450156 antibody
  • AU019207 antibody
  • bap-1 antibody
  • bap1 antibody
  • ding antibody
  • fa19h05 antibody
  • hipi3 antibody
  • Ring1B antibody
  • ring2 antibody
  • wu:fa19h05 antibody
  • wz4556 antibody

Protein level used designations for RNF2

E3 ubiquitin-protein ligase RING2 , ring finger protein 1b , wz4566 , RING finger protein 1B , HIP2-interacting protein 3 , RING finger protein BAP-1 , huntingtin-interacting protein 2-interacting protein 3 , protein DinG , RING1b

GENE ID SPECIES
327035 Danio rerio
424452 Gallus gallus
457581 Pan troglodytes
100174504 Pongo abelii
6045 Homo sapiens
480042 Canis lupus familiaris
540090 Bos taurus
19821 Mus musculus
304850 Rattus norvegicus
100127274 Xenopus laevis
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