RNF2 antibody (Middle Region)

Catalog No. ABIN2775705

The Rabbit Polyclonal anti-RNF2 antibody (ABIN2775705) specifically detects RNF2 in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Horse, Rabbit and Guinea Pig samples.

Quick Overview for RNF2 antibody (Middle Region) (ABIN2775705)

Target: RNF2 (Ring Finger Protein 2 (RNF2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-RNF2 Antibody

Binding Specificity: Middle Region

Purpose: RNF2 Antibody - middle region

Sequence: LVFRPHPTLM EKDDSAQTRY IKTSGNATVD HLSKYLAVRL ALEELRSKGE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against RNF2. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RNF2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8110857

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for RNF2

Target: RNF2 (Ring Finger Protein 2 (RNF2))

Alternative Name: RNF2

Background:

Background Information: Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by RNF2 is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.

Gene Name: Ring finger protein 2

Alternative Symbols: BAP1, DING, BAP-1, HIPI3, RING2, RING1B

Protein Name: E3 ubiquitin-protein ligase RING2

Molecular Weight: 29kDa

Gene ID: 6045

NCBI Accession: NP_009143

UniProt: Q5TEN1