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anti-Ring Finger Protein 20 (RNF20) Antibodies

The protein encoded by RNF20 shares similarity with BRE1 of S. Additionally we are shipping RNF20 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RNF20 109331 Q5DTM8
RNF20 56254 Q5VTR2
RNF20 313216  
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Top anti-RNF20 Antibodies at antibodies-online.com

Showing 10 out of 66 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-RNF20 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-RNF20 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged RNF20 is approximately 0.03 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB RNF20 Antibody (N-term) (ABIN658113) western blot analysis in 293 cell line lysates (35 µg/lane). This demonstrates the RNF20 antibody detected the RNF20 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 14 Days
$527.15
Details
Human Rabbit Un-conjugated IF, IHC (p), ELISA, WB   50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB RNF20 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details

RNF20 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-RNF20 Antibodies

  1. Human Monoclonal RNF20 Primary Antibody for ELISA, WB - ABIN393482 : Svendsen, Smogorzewska, Sowa, OConnell, Gygi, Elledge, Harper: Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair. in Cell 2009 (PubMed)
    Show all 5 references for ABIN393482

  2. Chicken Polyclonal RNF20 Primary Antibody for WB - ABIN2774764 : Barber, McManus, Yuen, Reis, Parmigiani, Shen, Barrett, Nouhi, Spencer, Markowitz, Velculescu, Kinzler, Vogelstein, Lengauer, Hieter: Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)

More Antibodies against RNF20 Interaction Partners

Mouse (Murine) Ring Finger Protein 20 (RNF20) interaction partners

  1. RNF20 plays a critical role in the regulation of hepatic lipid metabolism by modulating the protein stability and transcriptional activity of SREBP1c (show SREBF1 Antibodies) during hormonal changes.

  2. results suggested that RNF20 may play roles in adipocyte differentiation by stimulating ubiquitin-proteasome-dependent degradation of AP-2alpha (show TFAP2A Antibodies).

  3. Bre1a-negative cells in the ventricular zone of early embryonic brains remain undifferentiated and are selected as self-renewing neural stem cells

  4. model whereby cotranscriptional recruitment of Rnf20 at MLL (show MLL Antibodies)-fusion target genes leads to amplification of Dot1l (show DOT1L Antibodies)-mediated H3K79 methylation, thereby rendering leukemia cells dependent on Rnf20 to maintain their oncogenic transcriptional program

  5. Loss of Bre1 (RNF20) disrupts gene silencing at telomeric chromatin. Most of the genomic instability in the Bre1-deficient cells is attributed to the formation of R-loops.

  6. We show that Bre1 (human BRE1A/B (RNF20/40) and mouse Bre1a/b (Rnf20/40)) acts as an important suppressor of chromosomal instability

  7. the observed defects in the radiation response of Bre1a/b-deficient cells

Human Ring Finger Protein 20 (RNF20) interaction partners

  1. It was observed that RE-IIBP induces MEIS1 (show MEIS1 Antibodies)-mediated apoptosis, which was dependent on H2BK120 ubiquitination by RNF20.

  2. A primary role for FACT in RNF20 recruitment chromatin remodeling for initiation of homologous recombination repair.

  3. Together, these results indicate that human adenovirus E1A (show BCKDHA Antibodies) uses hBre1 to recruit the hPaf1 (show PAF1 Antibodies) complex in order to optimally activate viral early transcription by enhancing transcriptional elongation.

  4. The ability of E1A (show BCKDHA Antibodies) to target hBre1 to simultaneously repress cellular IFN dependent transcription while activating viral transcription

  5. model whereby cotranscriptional recruitment of Rnf20 at MLL (show MLL Antibodies)-fusion target genes leads to amplification of Dot1l (show DOT1L Antibodies)-mediated H3K79 methylation, thereby rendering leukemia cells dependent on Rnf20 to maintain their oncogenic transcriptional program

  6. We show that Bre1 (human BRE1A/B (RNF20/40) and mouse Bre1a/b (Rnf20/40)) acts as an important suppressor of chromosomal instability

  7. our results suggest that RNF20 and RNF40, either via ubiquitylation of H2B or other targets, are coupled to the proliferation of prostate cancer cells.

  8. Studies indicate that H2B monoubiquitylation is driven primarily by an E3 ubiquitin ligase (show MUL1 Antibodies) composed of the two RING finger (show PCGF1 Antibodies) proteins RNF20 and RNF40 (show RNF40 Antibodies).

  9. RNF20, presumably via H2Bub, selectively represses oncogenic genes by interfering with chromatin recruitment of TFIIS (show TCEA1 Antibodies), a factor capable of relieving stalled RNA polymerase II. RNF20 inhibits the interaction between TFIIS (show TCEA1 Antibodies) and the PAF1 (show PEX2 Antibodies) complex.

  10. RNF20-mediated H2B ubiquitination at DSBs plays a critical role in HRR through chromatin remodeling

RNF20 Antigen Profile

Protein Summary

The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. This gene selectively suppresses the expression of some genes by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS).

Gene names and symbols associated with RNF20

  • ring finger protein 20 (RNF20) antibody
  • ring finger protein 20 (Rnf20) antibody
  • ring finger protein 20, E3 ubiquitin protein ligase (RNF20) antibody
  • ring finger protein 20, E3 ubiquitin protein ligase (Rnf20) antibody
  • 4833430L21Rik antibody
  • AW540162 antibody
  • BRE1 antibody
  • BRE1A antibody
  • C79397 antibody
  • hBRE1 antibody
  • mKIAA4116 antibody

Protein level used designations for RNF20

BRE1-A , E3 ubiquitin-protein ligase BRE1A , BRE1 E3 ubiquitin ligase homolog , homolog of S. cerevisiae BRE1

GENE ID SPECIES
513326 Bos taurus
109331 Mus musculus
56254 Homo sapiens
427310 Gallus gallus
474788 Canis lupus familiaris
313216 Rattus norvegicus
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