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anti-ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 4 (ST8SIA4) Antibodies

The protein encoded by ST8SIA4 catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). Additionally we are shipping ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 4 Kits (26) and ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 4 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ST8SIA4 7903 Q92187
ST8SIA4 20452 Q64692
ST8SIA4 116696  
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Top anti-ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 4 Antibodies at antibodies-online.com

Showing 10 out of 37 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-ST8SIA4 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB ST8SIA4 Antibody (Center) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. ST8SIA4 Antibody (Center) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ST8SIA4 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Yeast Rabbit Un-conjugated EIA, WB Western blot analysis of TM yeast Pst1 protein (50 ng) with Pst1 Antibody  at 1 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-St8sia4 AntibodyTitration: 1.0 µg/mL  Positive Control: Rat Testis 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of ST8SIA4 Antibody (Center) (ABIN653728) in HL-60 cell line lysates (35 µg/lane). ST8SIA4 (arrow) was detected using the purified polyclonal antibody. Western blot analysis of ST8SIA4 Antibody (Center) (ABIN653728) in mouse spleen tissue lysates (35 µg/lane). ST8SIA4 (arrow) was detected using the purified polyclonal antibody. ST8SIA4 Antibody (Center) (ABIN653728) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB ST8SIA4 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Alkaline Phosphatase (AP) FACS, IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Rat Rabbit Un-conjugated WB   50 μg Log in to see 8 to 10 Days
$551.83
Details

ST8SIA4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
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Mouse (Murine)


Rat (Rattus)


Top referenced anti-ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 4 Antibodies

  1. Yeast Polyclonal ST8SIA4 Primary Antibody for EIA, WB - ABIN1450017 : Luallen, Lin, Fu, Cai, Agrawal, Mboudjeka, Lee, Montefiori, Smith, Doms, Geng: An engineered Saccharomyces cerevisiae strain binds the broadly neutralizing human immunodeficiency virus type 1 antibody 2G12 and elicits mannose-specific gp120-binding antibodies. in Journal of virology 2008 (PubMed)
    Show all 4 references for ABIN1450017

  2. Human Polyclonal ST8SIA4 Primary Antibody for IHC (p), WB - ABIN954963 : Foley, Swartzentruber, Colley: Identification of sequences in the polysialyltransferases ST8Sia II and ST8Sia IV that are required for the protein-specific polysialylation of the neural cell adhesion molecule, NCAM. in The Journal of biological chemistry 2009 (PubMed)
    Show all 2 references for ABIN954963

  3. Chicken Polyclonal ST8SIA4 Primary Antibody for WB - ABIN2783461 : Schreiber, Giehl, Kastilan, Hasel, Mühlenhoff, Adler, Wedlich, Menke: Polysialylated NCAM represses E-cadherin-mediated cell-cell adhesion in pancreatic tumor cells. in Gastroenterology 2008 (PubMed)

More Antibodies against ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 4 Interaction Partners

Human ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 4 (ST8SIA4) interaction partners

  1. ST8SIA4 gene is involved in the development of multidrug resistance via PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) pathway in chronic myeloid leukemia (show BCL11A Antibodies).

  2. this study indicated that sialylation involved in the development of MDR of AML (show RUNX1 Antibodies) cells probably through ST3GAL5 (show ST3GAL5 Antibodies) or ST8SIA4 regulating the activity of PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) signaling and the expression of P-gp (show ABCB4 Antibodies) and MRP1 (show MDM4 Antibodies).

  3. ST8SiaIV synthesized polySia selectively on a NRP2 (show NELL2 Antibodies) glycoform that was characterized by the presence of sialylated core 1 and core 2 O-glycans.

  4. The ST8SiaIV/PST polybasic region plays a critical role in substrate recognition.

  5. polysialylated NCAM (show NCAM1 Antibodies) persistence, up-regulated polysialyltransferase-1 mRNA and previously uncovered defective myelin-associated glycoprotein (show MAG Antibodies) may be early pathogenetic events in adult-onset autosomal-dominant leukodystrophy

  6. SIAT8D has a role in neural development and sialic acid synthesis on NCAM (show NCAM1 Antibodies)

  7. Pancreatitis risk was highest in individuals with abnormalities in pancreatic duct(CFTR (show CFTR Antibodies)) and acini (PST1) indicating that PST1 is a modifier gene for CFTR (show CFTR Antibodies)-related idiopathic chronic pancreatitis.

  8. The upregulation of ST8SIA4 and the donwregulation of ST8SIA2 (show ST8SIA2 Antibodies) by valproic acid in HUVEC and tumor cell lines are reported.

  9. polysialyltransferase ST8Sia IV/PST recognizes specific amino acids in the first fibronectin (show FN1 Antibodies) type III repeat of the neural cell adhesion molecule (show MCAM Antibodies)

  10. PSA (show PLAG1 Antibodies)-NCAM (show NCAM1 Antibodies) and ST8Sia-II (show ST8SIA2 Antibodies)/IV Expression Is Increased in Pancreatic Carcinomas

Pig (Porcine) ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 4 (ST8SIA4) interaction partners

  1. Pig cDNA provides a basis for uncovering the roles of ST8Sia IV during piglet development and maturation.

Mouse (Murine) ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 4 (ST8SIA4) interaction partners

  1. SULT1A1 (show SULT1A1 Antibodies) is responsible for bioactivation of food genotoxicants 5-hydroxymethylfurfural and furfuryl alcohol.

  2. NCAM (show NCAM1 Antibodies)-140 significantly promoted cell proliferation, motility and migration, while polysialylation of NCAM (show NCAM1 Antibodies)-140 catalyzed by STX (show ST8SIA2 Antibodies), but not by PST, enhanced NCAM (show NCAM1 Antibodies)-mediated cell migration, but not cell proliferation or motility.

  3. ST8SiaIV synthesized polySia selectively on a NRP2 (show NRP2 Antibodies) glycoform that was characterized by the presence of sialylated core 1 and core 2 O-glycans.

  4. Results indicate that the polySTs ST8SiaII (show ST8SIA2 Antibodies) and ST8SiaIV not only recognize an acidic patch in the FN1 (show FN1 Antibodies) domain of NCAM (show NCAM1 Antibodies) but also must contact sequences in the Ig5 domain for polysialylation of Ig5 N-glycans to occur.

  5. the negative and positive effects of ST8SiaIV overexpression observed during peripheral nerve regeneration suggest that an optimized time- and differentiation-dependent control of expression in Schwann cells may further improve nerve regeneration

  6. While both ST8SiaII (show ST8SIA2 Antibodies) and ST8SiaIV mRNA levels decrease around the time of eye opening in mouse visual cortex, only ST8SiaII (show ST8SIA2 Antibodies) mRNA level reduction is regulated by sensory experience

  7. ST8Sia4 knockout mice display a decreased motivation in social interaction. This deficit can be partly explained by olfactory deficits and was associated with a clear decrease in PSA (show NPEPPS Antibodies)-NCAM (show NCAM1 Antibodies) expression in all brain regions analyzed.

  8. This study demonistrated that mice lacking St8siaIV polysialyltransferase have an accelerated onset of remyelination after cuprizone-induced demyelination.

  9. In summary, the data suggest that the polysialic acid-neural cell adhesion molecule (show MCAM Antibodies) system is a putative target for the modulation of

  10. Focusing on the cerebral cortex, our results indicate that ST8SiaIV is solely responsible for PSA (show NPEPPS Antibodies) expression in mature interneurons and in most regions of cortical neuropil.

ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 4 (ST8SIA4) Antigen Profile

Protein Summary

The protein encoded by this gene catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). The encoded protein, which is a member of glycosyltransferase family 29, is a type II membrane protein that may be present in the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ST8SIA4

  • ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 (ST8SIA4) antibody
  • ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 (St8sia4) antibody
  • sulfotransferase family 1A, phenol-preferring, member 1 (Sult1a1) antibody
  • AI266890 antibody
  • PST antibody
  • PST-1 antibody
  • PST1 antibody
  • SIAT8-D antibody
  • Siat8d antibody
  • ST1A1 antibody
  • ST8Sia-IV antibody
  • ST8SiaIV antibody
  • Stp antibody
  • Stp1 antibody

Protein level used designations for ST8SIA4

CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase , sialyltransferase 8D (alpha-2, 8-polysialyltransferase) , CMP-N-acetylneuraminate-poly-alpha-2,8-sialyl transferase , SIAT8-D , ST8SiaIV , alpha-2,8-sialyltransferase 8D , polysialyltransferase-1 , sialyltransferase 8 (alpha-2, 8-polysialytransferase) D , sialyltransferase 8D , sialyltransferase St8Sia IV , sialytransferase St8Sia IV , alpha-2,8-polysialyltransferase IV , ST8Sia IV , sialyltransferase 8 (alpha-2, 8-sialyltransferase) D , polysialyltransferase , sialyltransferase 8 (alpha-2 8-polysialyltransferase) D , sialyltransferase 8 (alpha-2 8-polysialytransferase) D , sialyltransferase 8 (alpha-2, 8-polysialyltransferase) D , sialyltransferase 8 (alpha-2, 8-sialytransferase) D , polysialyltransferase 1 , ST1A4 , aryl sulfotransferase , arylsulfotransferase ST1A4 , mSTp1 , phenol sulfotransferase , phenol/aryl sulfotransferase , sulfokinase , sulfotransferase 1A1 , sulfotransferase, phenol preferring 1

GENE ID SPECIES
374155 Gallus gallus
7903 Homo sapiens
488886 Canis lupus familiaris
641356 Sus scrofa
407768 Bos taurus
20452 Mus musculus
116696 Rattus norvegicus
461971 Pan troglodytes
101112314 Ovis aries
20887 Mus musculus
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