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anti-Sestrin 2 (SESN2) Antibodies

SESN2 encodes a member of the sestrin family of PA26-related proteins. Additionally we are shipping Sestrin 2 Kits (12) and Sestrin 2 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SESN2 83667 P58004
SESN2 230784 P58043
SESN2 502988  
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Top anti-Sestrin 2 Antibodies at antibodies-online.com

Showing 10 out of 54 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis of Sestrin-2 Antibody (Center) (ABIN652222) in 293 cell line lysates (35 µg/lane). Sestrin-2 (arrow) was detected using the purified polyclonal antibody. Sestrin-2 Antibody (Center) (ABIN652222) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB (LEFT) Western blot analysis of Sestrin-2 Antibody (Center) in 293 cell line lysates (35ug/lane). Sestrin-2 (arrow) was detected using the purified Pab. (RIGHT) Western blot analysis of SESN2 (arrow) using rabbit polyclonal Sestrin-2 Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the SESN2 gene (Lane 2). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$456.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IF, IHC (p), IP, ELISA, WB Immunoperoxidase of monoclonal antibody to SESN2 on formalin-fixed paraffin-embedded human ovary, clear cell carcinoma. [antibody concentration 3 ug/ml] SESN2 monoclonal antibody (M03), clone 3B8 Western Blot analysis of SESN2 expression in K-562 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated DB 50 μg Log in to see 7 to 9 Days
$285.71
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of to SES2 on HeLa cell . SESN2 monoclonal antibody (M03), clone 3B8 Western Blot analysis of SESN2 expression in K-562. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IF, IHC, WB 100 μL Log in to see 14 Days
$527.15
Details

SESN2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Sestrin 2 Antibodies

  1. Human Polyclonal Sestrin 2 Primary Antibody for EIA, WB - ABIN492725 : Maiuri, Malik, Morselli, Kepp, Criollo, Mouchel, Carnuccio, Kroemer: Stimulation of autophagy by the p53 target gene Sestrin2. in Cell cycle (Georgetown, Tex.) 2009 (PubMed)
    Show all 8 references for ABIN492725

  2. Human Monoclonal Sestrin 2 Primary Antibody for IF, IHC (p) - ABIN566510 : Liu, Lee, Lee: Association of platelet-derived growth factor receptor ? accumulation with increased oxidative stress and cellular injury in sestrin 2 silenced human glioblastoma cells. in FEBS letters 2011 (PubMed)
    Show all 2 references for ABIN566510

  3. Human Polyclonal Sestrin 2 Primary Antibody for EIA, WB - ABIN453824 : Budanov, Sablina, Feinstein, Koonin, Chumakov: Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD. in Science (New York, N.Y.) 2004 (PubMed)

More Antibodies against Sestrin 2 Interaction Partners

Human Sestrin 2 (SESN2) interaction partners

  1. The up-regulation of SESN2 by mitochondrial dysfunction requires binding to ATF4 (show ATF4 Antibodies).

  2. Sesn2 has two subdomains. The N-terminal domain reduces alkylhydroperoxide radicals through its helix-turn-helix oxidoreductase (show TXNRD1 Antibodies) motif, and the C-terminal domain interacts with GATOR2 and subsequently inhibits mTORC1.

  3. SESN2-AMPK (show PRKAA1 Antibodies) signaling could exert a protective effect against glucose deprivation-induced cell death and that this effect is mediated by restoration of mitochondrial function.

  4. Sesn2 is a potential tumor suppressor in lung epithelial cells. The expression level of Sesn2 may serve as a prognostic marker for Chinese lung cancer patients in the clinic.

  5. The findings suggested that a decreased expression of sestrin 2 is associated with an unfavorable prognosis, which suggests that it is a novel and crucial predictor for colorectal cancer metastasis.

  6. an AMPK (show PRKAA1 Antibodies)-independent mechanism of mTORC1 inhibition by Sestrins mediated by their interaction with GATOR2, is reported.

  7. GAA (show GAA Antibodies) promotes FoxO3 (show FOXO3 Antibodies) nuclear translocation and binding to the SESN2 enhancer.

  8. Data indicate that inactivation of Sestrin 2 (Sesn2) or nuclear factor erythroid 2-related factor 2 (Nrf2 (show NFE2L2 Antibodies)) induced reactive oxygen species-mediated proteasomal inhibition and platelet-derived growth factor receptor beta (show PDGFRB Antibodies) (Pdgfrbeta) accumulation.

  9. Sesn2 is oncogenic in skin squamous cell carcinoma and melanoma.

  10. knockdown of SESN2 using small RNA interference promotes cellular toxicity of angiotensin II, as well as a reduction in cell viability, exacerbation of oxidative stress, and stimulation of apoptosis.

Mouse (Murine) Sestrin 2 (SESN2) interaction partners

  1. suggest that TLR-mediated Sesn2 induction is dependent on AP-1 (show JUN Antibodies), Nrf2 (show NFE2L2 Antibodies), and the inhibition of ubiquitin-mediated degradation of Sesn2 and might protect cells against endotoxin toxicity

  2. an AMPK (show PRKAA1 Antibodies)-independent mechanism of mTORC1 inhibition by Sestrins mediated by their interaction with GATOR2, is reported.

  3. Study found that Sestrins (1,2 and 3) can inhibit mTORC1 signaling in the absence of AMPK (show PRKAA1 Antibodies) or TSC2 (show TSC2 Antibodies). Surprisingly, when coexpressed with a GTP (show AK3 Antibodies)-bound constitutively active form of RagB (show RRAGB Antibodies) (RagBQ99L), Sestrins potentiate mTORC1 signaling in the absence of amino acids.

  4. Sestrin2 plays an important role in cardioprotection against I/R injury, serving as an LKB1 (show STK11 Antibodies)-AMPK (show PRKAA1 Antibodies) scaffold to initiate AMPK (show PRKAA1 Antibodies) activation during ischemic insults

  5. Data indicate that sestrin2 expression is upregulated by dopamine D2 receptor (show DRD2 Antibodies).

  6. this study identifies ULK1 as a new p62 Ser403 kinase and establishes Sestrin2 as a promoter of ULK1-mediated p62 phosphorylation.

  7. Sesn2 controls reactive oxygen species-dependent neuropathic pain signaling after peripheral nerve injury.

  8. results imply that SESN2 could serve as both a biomarker and as a drug target in the clinical management of COPD (show ARCN1 Antibodies)

  9. Ablation of Sesn2 blocked Keap1 (show KEAP1 Antibodies) degradation and Nrf2 (show NFE2L2 Antibodies) activation induced by refeeding and thereby increased the susceptibility of the liver to oxidative damage resulting from the acute stimulation of lipogenesis associated with refeeding.

  10. Sestrin2--encoded by the Sesn2 locus, whose expression is induced upon hypernutrition--maintains metabolic homeostasis in liver of obese mice.

Sestrin 2 (SESN2) Antigen Profile

Protein Summary

This gene encodes a member of the sestrin family of PA26-related proteins. The encoded protein may function in the regulation of cell growth and survival. This protein may be involved in cellular response to different stress conditions.

Gene names and symbols associated with anti-Sestrin 2 (SESN2) Antibodies

  • sestrin 2 (sesn2) antibody
  • sestrin 2 (SESN2) antibody
  • sestrin 2 (LOC100353543) antibody
  • sestrin 2 (Sesn2) antibody
  • HI95 antibody
  • MGC81239 antibody
  • RGD1566319 antibody
  • Ses2 antibody
  • SESN2 antibody
  • SEST2 antibody
  • Sestrin-2 antibody

Protein level used designations for anti-Sestrin 2 (SESN2) Antibodies

sestrin 2 , sestrin-2 , sestrin-2-like , hypoxia induced gene 95

GENE ID SPECIES
414641 Xenopus laevis
469167 Pan troglodytes
487335 Canis lupus familiaris
558966 Danio rerio
716904 Macaca mulatta
733499 Xenopus (Silurana) tropicalis
100056552 Equus caballus
100172219 Pongo abelii
100353543 Oryctolagus cuniculus
100397149 Callithrix jacchus
100469808 Ailuropoda melanoleuca
100592235 Nomascus leucogenys
83667 Homo sapiens
230784 Mus musculus
502988 Rattus norvegicus
509863 Bos taurus
Selected quality suppliers for anti-Sestrin 2 (SESN2) Antibodies
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