Sestrin 2 antibody (AA 1-480)

Catalog No. ABIN566510

Product Details anti-Sestrin 2 Antibody

Target: Sestrin 2 (SESN2)

Binding Specificity: AA 1-480

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Sestrin 2 antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), ELISA, Western Blotting (WB)

Purpose: Mouse monoclonal antibody raised against a full length recombinant SESN2.

Sequence: MIVADSECRA ELKDYLRFAP GGVGDSGPGE EQRESRARRG PRGPSAFIPV EEVLREGAES LEQHLGLEAL MSSGRVDNLA VVMGLHPDYF TSFWRLHYLL LHTDGPLASS WRHYIAIMAA ARHQCSYLVG SHMAEFLQTG GDPEWLLGLH RAPEKLRKLS EINKLLAHRP WLITKEHIQA LLKTGEHTWS LAELIQALVL LTHCHSLSSF VFGCGILPEG DADGSPAPQA PTPPSEQSSP PSRDPLNNSG GFESARDVEA LMERMQQLQE SLLRDEGTSQ EEMESRFELE KSESLLVTPS ADILEPSPHP DMLCFVEDPT FGYEDFTRRG AQAPPTFRAQ DYTWEDHGYS LIQRLYPEGG QLLDEKFQAA YSLTYNTIAM HSGVDTSVLR RAIWNYIHCV FGIRYDDYDY GEVNQLLERN LKVYIKTVAC YPEKTTRRMY NLFWRHFRHS EKVHVNLLLL EARMQAALLY ALRAITRYMT

Cross-Reactivity: Human

Immunogen: SESN2 (AAH13304.1, 1 a.a. ~ 480 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 3B8

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Product Quality tested by: Antibody Reactive Against Recombinant Protein.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-Sestrin 2 antibody (ABIN566510)

Li, Sun, Wu, Chen, Deng, Jiang, Feng, Pan, Zhang, Zeng, Zhu: "The inhibition of autophagy sensitises colon cancer cells with wild-type p53 but not mutant p53 to topotecan treatment." in: PLoS ONE, Vol. 7, Issue 9, pp. e45058, (2012) (PubMed).

Liu, Lee, Lee: "Association of platelet-derived growth factor receptor ? accumulation with increased oxidative stress and cellular injury in sestrin 2 silenced human glioblastoma cells." in: FEBS letters, Vol. 585, Issue 12, pp. 1853-8, (2011) (PubMed).

Target Details for Sestrin 2

Target: Sestrin 2 (SESN2)

Alternative Name: SESN2 (SESN2 Products)

Synonyms: HI95 antibody, SES2 antibody, SEST2 antibody, Ses2 antibody, MGC81239 antibody, SESN2 antibody, sestrin-2 antibody, hi95 antibody, ses2 antibody, sest2 antibody, Sestrin-2 antibody, RGD1566319 antibody, sestrin 2 antibody, sestrin 2 L homeolog antibody, SESN2 antibody, Sesn2 antibody, sesn2.L antibody, sesn2 antibody

Background: Full Gene Name: sestrin 2
Synonyms: DKFZp761M0212,DKFZp761M02121,HI95,SES2,SEST2

Gene ID: 83667