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SP7 encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Additionally we are shipping SP7 Kits (21) and SP7 Proteins (4) and many more products for this protein.
Showing 10 out of 33 products:
Human Polyclonal SP7 Primary Antibody for IF (p), IHC (p) - ABIN737811
Chen, Lazarenko, Zhang, Blackburn, Ronis, Badger: Diet-derived phenolic acids regulate osteoblast and adipocyte lineage commitment and differentiation in young mice. in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2014
Show all 2 references for ABIN737811
Cow (Bovine) Polyclonal SP7 Primary Antibody for IHC, WB - ABIN2779512
Rich, Rosová, Nolta, Myckatyn, Sandell, McAlinden: Upregulation of Runx2 and Osterix during in vitro chondrogenesis of human adipose-derived stromal cells. in Biochemical and biophysical research communications 2008
Cow (Bovine) Polyclonal SP7 Primary Antibody for IHC, WB - ABIN2777381
Milona, Gough, Edgar: Expression of alternatively spliced isoforms of human Sp7 in osteoblast-like cells. in BMC genomics 2004
Human Polyclonal SP7 Primary Antibody for WB - ABIN2777382
Morsczeck: Gene expression of runx2, Osterix, c-fos, DLX-3, DLX-5, and MSX-2 in dental follicle cells during osteogenic differentiation in vitro. in Calcified tissue international 2006
Human Polyclonal SP7 Primary Antibody for EIA - ABIN191530
Gao, Jheon, Nourkeyhani, Kobayashi, Ganss: Molecular cloning, structure, expression, and chromosomal localization of the human Osterix (SP7) gene. in Gene 2004
FGF and Wnt (show WNT2 Antibodies)/beta-Catenin (show CTNNB1 Antibodies) pathways act in part by directing transcription of osx to promote osteoblast differentiation at sites of bone formation.
Data show the endogenous sp7 gene expression in the otic placode and vesicle, and in forming skeletal structures in Tg(sp7:EGFP)b1212 line.
Data suggest that beta-catenin (beta-cat) signaling upregulates the expression of osterix (OSX) in pre-osteoblastic and bone marrow stromal cells.
The 2 genes RUNX1 (show RUNX1 Antibodies) and SP7 resulted differently expressed in cells cultured on metallic supports if compared with the expression recorded for OIC
c-Src (show SRC Antibodies) signaling modulates osteoblast differentiation at least in part through phosphorylation of Osterix.
Pin1 (show PIN1 Antibodies) regulates the osteogenic activity of Osterix.
Runx2 (show RUNX2 Antibodies)-Sp7 molecular complex functionally cooperate for maximal induction of cell-phenotype-restricted genes
Osterix is a novel target of protein kinase A, and protein kinase A modulates osteoblast differentiation partially through the regulation of Osterix.
results provide a molecular description of a mechanism for Osx (show MID1 Antibodies) and Runx2 (show RUNX2 Antibodies) transcriptional cooperation that is subject to further regulation by MAPK (show MAPK1 Antibodies)-activating signals during osteogenesis.
In adamantinomatous craniopharyngioma, Bmp2 (show BMP2 Antibodies) was expressed primarily in the stellate reticulum and whorl-like array cells; Runx2 (show RUNX2 Antibodies) and Osterix tended to be expressed in calcification-related epithelia.
MiR (show MLXIP Antibodies)-31, controls Osterix expression through association to the 3' untranslated region of this transcription factor.
These results suggest that Osterix is a novel target of CaMKII (show CAMK2G Antibodies) and the activity of Osterix can be modulated by a novel mechanism involving CaMKII (show CAMK2G Antibodies) during osteoblast differentiation.
cells expressing osterix are mesenchymal progenitors contributing to all relevant cell types during morphogenesis.
Results propose that Utx (show KDM6A Antibodies) plays important roles in osteoblast differentiation by controlling the expressions of Runx2 (show RUNX2 Antibodies) and Osterix.
Decreased expression of Osterix, as well as impaired TGFbeta (show TGFB1 Antibodies) and BMP2 (show BMP2 Antibodies) signaling, contribute to the observed osteopenic bone phenotype of TIEG1 (show KLF10 Antibodies) KO mice.
Intermittent stretching promotes osteogenic differentiation of bone marrow derived mesenchymal stem cells; the p38MAPK (show MAPK14 Antibodies)-osterix pathway has an important role in the control of osteogenesis related gene expression.
CHIP targets Osx for ubiquitination and degradation in osteoblasts after chronic exposure to TNF-alpha (show TNF Antibodies).
conclude that OSX, one of the key downstream molecules of NFIC (show NFIC Antibodies), plays a critical role in root, but not crown, formation
Cbl-b and c-Cbl regulate the degradation of Osterix through the ubiquitin-proteasome pathway.
The key role of Osx in control of cementoblast proliferation and differentiation is to maintain a low level of Wnt (show WNT2 Antibodies)-beta-catenin (show CTNNB1 Antibodies) via direct up-regulation of DKK1 (show DKK1 Antibodies).
These data suggest that Osx-Cre containing controls should be used for both in vivo and in vitro skeletal analyses of conditional knockout mice generated with this Osx-Cre mouse strain
This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein is a bone specific transcription factor and is required for osteoblast differentiation and bone formation.
transcription factor Sp7
, transcription factor osterix
, Sp7 transcription factor
, transcription factor Sp7-like
, zinc finger protein osterix
, trans-acting transcription factor 7