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SP7 Products

(Sp7 Transcription Factor (SP7))
This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein is a bone specific transcription factor and is required for osteoblast differentiation and bone formation.[provided by RefSeq, Jul 2010].

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Featured SP7 Categories

SP7 Antibodies

High quality antibodies with extensive validation data.

SP7 ELISA Kits

Reliable ELISA kits for a wide range of species.

SP7 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SP7 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rabbit
Application ELISA, IF (cc), IF (p), IHC (fro), IHC (p), WB
Validations
  • (11)
  • (5)
Cat. No. ABIN737811
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application IHC, WB
Validations
  • (1)
  • (4)
Cat. No. ABIN2777381
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
Cat. No. ABIN7270510
Quantity 100 μL
Datasheet Datasheet

Recommended SP7 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970381
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959649
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6959650
Quantity 96 tests
Datasheet Datasheet

Recommended SP7 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3077254
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3127212
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321042
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our SP7 products

Zhang, Xie, Wang, Zhang, Yang: "Anti-osteoporosis activity of Sanguinarine in preosteoblast MC3T3-E1 cells and an ovariectomized rat model." in: Journal of cellular physiology, Vol. 233, Issue 6, pp. 4626-4633, (2018) (PubMed).

Li, Xu, Xing, Qian, Chen, Gu, Guo, Lai, Zhao, Li, Wang, Wang, Deng: "A Conditional Knockout Mouse Model Reveals a Critical Role of PKD1 in Osteoblast Differentiation and Bone Development." in: Scientific reports, Vol. 7, pp. 40505, (2017) (PubMed).

Qian, Yan, Bai, Chen, Zhang, Yao, Xia: "Differential circRNA expression profiles during the BMP2-induced osteogenic differentiation of MC3T3-E1 cells." in: Biomedicine & pharmacotherapy, Vol. 90, pp. 492-499, (2017) (PubMed).

Agarwal, Loder, Cholok, Peterson, Li, Fireman, Breuler, Hsieh, Ranganathan, Hwang, Drake, Li, Chan, Longaker, Levi: "Local and Circulating Endothelial Cells Undergo Endothelial to Mesenchymal Transition (EndMT) in Response to Musculoskeletal Injury." in: Scientific reports, Vol. 6, pp. 32514, (2016) (PubMed).

Tang, Tan, Ni, Wang, Zhu, Fan, Chen, Yang, Zhang: "Comparison of ectopic bone formation process induced by four calcium phosphate ceramics in mice." in: Materials science & engineering. C, Materials for biological applications, Vol. 70, Issue Pt 2, pp. 1000-1010, (2016) (PubMed).

Agarwal, Loder, Sorkin, Li, Shrestha, Zhao, Mishina, James, Levi: "Analysis of Bone-Cartilage-Stromal Progenitor Populations in Trauma Induced and Genetic Models of Heterotopic Ossification." in: Stem cells (Dayton, Ohio), Vol. 34, Issue 6, pp. 1692-701, (2016) (PubMed).

Pérez-Campo, Santurtún, García-Ibarbia, Pascual, Valero, Garcés, Sañudo, Zarrabeitia, Riancho: "Osterix and RUNX2 are Transcriptional Regulators of Sclerostin in Human Bone." in: Calcified tissue international, Vol. 99, Issue 3, pp. 302-9, (2016) (PubMed).

Wang, He, Liu, Liu, Zhou, Hao, Sun, Wang: "Synergistic effects of overexpression of BMP‑2 and TGF‑β3 on osteogenic differentiation of bone marrow mesenchymal stem cells." in: Molecular medicine reports, Vol. 14, Issue 6, pp. 5514-5520, (2016) (PubMed).

Rajshankar, Wang, McCulloch: "Osteogenesis requires FAK-dependent collagen synthesis by fibroblasts and osteoblasts." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 31, Issue 3, pp. 937-953, (2016) (PubMed).

Ranganathan, Agarwal, Cholok, Loder, Li, Sung Hsieh, Wang, Buchman, Levi: "The role of the adaptive immune system in burn-induced heterotopic ossification and mesenchymal cell osteogenic differentiation." in: The Journal of surgical research, Vol. 206, Issue 1, pp. 53-61, (2016) (PubMed).

Synonyms and alternative names related to SP7

midline 1 (MID1), Sp7 transcription factor (SP7), Sp7 transcription factor (Sp7), Sp7 transcription factor (sp7), uncharacterized LOC100063836 (LOC100063836), Sp7 transcription factor L homeolog (sp7.L), Sp7 transcription factor 7 (Sp7), 6430578P22Rik, BBBG1, C22, FXY, GBBB1, MIDIN, OGS1, OI11, OI12, OS, osterix, OSX, Osx, osx, RNF59, SP7, sp7, TRIM18, XPRF, ZNFXY

Protein level used designations for SP7

  • RING finger protein 59
  • midline 1 RING finger protein
  • midline-1
  • putative transcription factor XPRF
  • tripartite motif protein TRIM18
  • tripartite motif-containing protein 18
  • zinc finger on X and Y, mouse, homolog of
  • transcription factor Sp7
  • zinc finger protein osterix
  • osterix
  • transcription factor osterix
  • Sp7 transcription factor
  • transcription factor Sp7-like
  • trans-acting transcription factor 7
  • Sp7 transcription factor 7
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