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anti-Sphingosine-1-Phosphate Receptor 4 (S1PR4) Antibodies

S1PR4 is a member of the endothelial differentiation, G-protein-coupled (EDG)) receptor gene family. Additionally we are shipping S1PR4 Kits (6) and S1PR4 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
S1PR4 8698 O95977
S1PR4 13611 Q9Z0L1
S1PR4 314649  
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Top anti-S1PR4 Antibodies at antibodies-online.com

Showing 10 out of 100 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from K562 cells, using EDG6 Antibody... Immunofluorescence analysis of HepG2 cells, using EDG6 Antibody. The p... 100 μg Log in to see 2 to 3 Days
$275.00
Details
Human Rabbit Un-conjugated IF, ELISA Immunofluorescence analysis of A549 cells, using EDG6 Antibody. The pi... 100 μg Log in to see 2 to 3 Days
$275.00
Details
Human Rabbit Un-conjugated WB EDG6 Antibody (R23) (ABIN652182) western blot analysis in NCI-H292 cel... EDG6 Antibody (R23) (ABIN652182) western blot analysis in mouse spleen... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated FACS, IF, WB 0.1 mg Log in to see 6 to 8 Days
$643.50
Details
Human Mouse FITC FACS, WB   0.1 mg Log in to see 6 to 8 Days
$643.50
Details
Human Rabbit Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$643.50
Details
Human Rabbit Un-conjugated IHC (p) Immunohistochemical staining of Lymph node using anti- EDG6 antibody A... 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated WB AP31093PU-N EDG6 antibody staining of HepG2 (A) whole cell lysate (30 ... 0.1 mL Log in to see 6 to 8 Days
$253.00
Details
Human Rabbit Un-conjugated IHC (p) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IF, ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details

S1PR4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
,
Mouse (Murine) , , , ,

Rat (Rattus) , , , ,

Top referenced anti-S1PR4 Antibodies

  1. Human Polyclonal S1PR4 Primary Antibody for WB - ABIN652182 : Contos, Ye, Sah, Chun: Tandem genomic arrangement of a G protein (Gna15) and G protein-coupled receptor (s1p(4)/lp(C1)/Edg6) gene. in FEBS letters 2002 (PubMed)
    Show all 4 references for ABIN652182

  2. Human Monoclonal S1PR4 Primary Antibody for FACS, WB - ABIN264452 : Yamazaki, Kon, Sato, Tomura, Sato, Yoneya, Okazaki, Okajima, Ohta: Edg-6 as a putative sphingosine 1-phosphate receptor coupling to Ca(2+) signaling pathway. in Biochemical and biophysical research communications 2000 (PubMed)
    Show all 3 references for ABIN264452

  3. Human Monoclonal S1PR4 Primary Antibody for FACS, IF - ABIN264453 : Van Brocklyn, Gräler, Bernhardt, Hobson, Lipp, Spiegel: Sphingosine-1-phosphate is a ligand for the G protein-coupled receptor EDG-6. in Blood 2000 (PubMed)
    Show all 3 references for ABIN264453

  4. Human Polyclonal S1PR4 Primary Antibody for WB - ABIN265012 : Takuwa, Okamoto, Takuwa, Gonda, Sugimoto, Sakurada: Subtype-specific, differential activities of the EDG family receptors for sphingosine-1-phosphate, a novel lysophospholipid mediator. in Molecular and cellular endocrinology 2001 (PubMed)
    Show all 3 references for ABIN265012

  5. Human Polyclonal S1PR4 Primary Antibody for IF, ELISA - ABIN1535592 : Gräler, Bernhardt, Lipp: EDG6, a novel G-protein-coupled receptor related to receptors for bioactive lysophospholipids, is specifically expressed in lymphoid tissue. in Genomics 1998 (PubMed)
    Show all 2 references for ABIN1535592

More Antibodies against S1PR4 Interaction Partners

Human Sphingosine-1-Phosphate Receptor 4 (S1PR4) interaction partners

  1. Ig-like transcript 7 is rapidly internalized upon receptor-mediated endocytosis of TLR7 (show TLR7 Antibodies)/9 ligands to allow high IFN-alpha (show IFNA Antibodies) production. This is antagonized by S1PR4 signaling, thus decreasing TLR-induced IFN-alpha (show IFNA Antibodies) secretion.

  2. S1P2 (show S1PR2 Antibodies) translocation to the nucleus is regulated by an autocrine loop involving S1P (show MBTPS1 Antibodies) and S1P4. In contrast, the translocation of Y416 phosphorylated c-Src (show SRC Antibodies) to the nucleus appears to be regulated by a mechanism that does not involve S1P3 (show S1PR3 Antibodies) or S1P4.

  3. analysis of novel potent and selective sphingosine-1-phosphate 4 receptor (S1P (show MBTPS1 Antibodies)-R) agonists

  4. findings highlight an important role for S1P (show MBTPS1 Antibodies)(4) and SK1 (show KCNN1 Antibodies) in ER(-) breast cancer progression.

  5. Data show that S1P4 uses HER2 (show ERBB2 Antibodies) to regulate extracellular signal regulated kinase-1/2 (show MAPK3 Antibodies) MDA-MB-453 breast cancer cells.

  6. Data report that sphingosine 1-ph (show MBTPS1 Antibodies)osphate receptor 4 (S1P(4)) is specifically up-regulated during the development of human megakaryocytes from progenitor cells

  7. Mutation of the ligand selectivity residue from glutamic acid to glutamine confers lysophosphatidic acid sensitivity with preference for short-chain species

  8. FOXO1 (show FOXO1 Antibodies) controls the expression of L-selectin (show SELL Antibodies) and EDG1 (show HEXIM1 Antibodies) and EDG6, receptors that regulate lymphocyte trafficking

Mouse (Murine) Sphingosine-1-Phosphate Receptor 4 (S1PR4) interaction partners

  1. Data shows a reduced abundance of pDC (show PDC Antibodies), particularly CD4 (show CD4 Antibodies)- pDC (show PDC Antibodies), in all organs of S1PR4-deficient vs. wildtype mice.

  2. analysis of novel potent and selective sphingosine-1-phosphate 4 receptor (S1P (show S1PR1 Antibodies)-R) agonists

  3. S1P4 signaling is involved in the regulation of dendritic cell function and TH17 T-cell differentiation. S1P4-mediated S1P (show S1PR1 Antibodies) signaling also modifies the course of various immune diseases in a murine model

  4. Megakaryocytes generated from S1P (show S1PR1 Antibodies)(4)-deficient murine bone marrow showed atypical and reduced formation of proplatelets in vitro.

  5. s1p (show S1PR1 Antibodies)(4) maps to mouse chromosome 10 and has similar tissue distribution to mouse Gna15 (show GNA15 Antibodies); transcription of the two genes may be under control of the same enhancer elements

  6. binding pocket of mS1P4 (mouse S1P4) has recognition sites for the anionic phosphate and cationic ammonium groups that are equidistant from the end of the non-polar tail

  7. S1P4 mediates immunosuppressive effects of S1P (show S1PR1 Antibodies) by inhibiting proliferation and secretion of effector cytokines, while enhancing secretion of the suppressive cytokine IL-10 (show IL10 Antibodies)

S1PR4 Antigen Profile

Protein Summary

This gene is a member of the endothelial differentiation, G-protein-coupled EDG receptor gene family. EDG receptors bind lysophospholipids or lysosphingolipids as ligands, and are involved in cell signalling in many different cell types. This EDG receptor gene is intronless and is specifically expressed in the lymphoid tissue.

Gene names and symbols associated with S1PR4

  • sphingosine-1-phosphate receptor 4 (S1PR4) antibody
  • sphingosine-1-phosphate receptor 4 (s1pr4) antibody
  • sphingosine-1-phosphate receptor 4 (S1pr4) antibody
  • Edg6 antibody
  • Lpc1 antibody
  • S1p4 antibody
  • SLP4 antibody

Protein level used designations for S1PR4

endothelial differentiation, G protein coupled receptor 6 , endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 6 , sphingosine 1-phosphate receptor 4 , sphingosine-1-phosphate receptor 4 , S1P receptor 4 , S1P receptor Edg-6 , endothelial differentiation G-protein coupled receptor 6 , endothelial differentiation, G-protein-coupled receptor 6 , sphingosine 1-phosphate receptor Edg-6 , S1p receptor 4 , endothelial differentiation G-protein-coupled receptor 6 , lysophospholipid receptor C1 , endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor 6

GENE ID SPECIES
455581 Pan troglodytes
539534 Bos taurus
612082 Canis lupus familiaris
712637 Macaca mulatta
100380986 Xenopus laevis
8698 Homo sapiens
13611 Mus musculus
314649 Rattus norvegicus
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