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anti-Stromal Interaction Molecule 2 (Stim2) Antibodies

Stim2 is a member of the stromal interaction molecule (STIM) family and likely arose, along with related family member STIM1, from a common ancestral gene. Additionally we are shipping Stim2 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Stim2 57620 Q9P246
Stim2 116873 P83093
Stim2 117087  
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Top anti-Stim2 Antibodies at antibodies-online.com

Showing 10 out of 73 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin fixed, paraffin embedded human kidney tissue stained with STIM2 Antibody (N-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of STIM2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. Western blot analysis of STIM2 Antibody (N-term) in UM cell line lysates (35ug/lane). This demonstrates the STIM2 antibody detected the STIM2 protein (arrow 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry of STIM2 in human spleen tissue with this product at 2.5 μg/ml. Western blot analysis of STIM2 in A-20 cell lysate AP30838PU-N at (A) 0.5 and (B) 1 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry of STIM2 in human spleen tissue with this product at 2.5 μg/ml. Western blot analysis of STIM2 in A-20 cell lysate with this product at (A) 0.5, (B) 1 and (C) 2 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated WB Host: Rabbit  Target Name: Stim2  Sample Tissue: Mouse Pancreas lysates  Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB STIM2 Antibody (N-term) (ABIN656476) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$368.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Human Small Intestine (formalin-fixed, paraffin-embedded) stained with STIM2 antibody ABIN461903 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Pancreas (formalin-fixed, paraffin-embedded) stained with STIM2 antibody ABIN461903 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC (p), WB Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with STIM2 antibody ABIN213834 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg Log in to see 15 to 19 Days
$455.07
Details

Stim2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
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Mouse (Murine)



Rat (Rattus)



Top referenced anti-Stim2 Antibodies

  1. Human Polyclonal Stim2 Primary Antibody for IHC, ELISA - ABIN1003212 : Luik, Lewis: New insights into the molecular mechanisms of store-operated Ca2+ signaling in T cells. in Trends in molecular medicine 2007 (PubMed)
    Show all 4 references for ABIN1003212

  2. Human Polyclonal Stim2 Primary Antibody for EIA, IHC (p) - ABIN954979 : Darbellay, Arnaudeau, Ceroni, Bader, Konig, Bernheim: Human muscle economy myoblast differentiation and excitation-contraction coupling use the same molecular partners, STIM1 and STIM2. in The Journal of biological chemistry 2010 (PubMed)
    Show all 3 references for ABIN954979

More Antibodies against Stim2 Interaction Partners

Human Stromal Interaction Molecule 2 (Stim2) interaction partners

  1. While STIM1 (show STIM1 Antibodies) is a full Orai1 (show ORAI1 Antibodies)-agonist, leucine-replacement of this crucial residue in STIM2 endows it with partial agonist properties, which may be critical for limiting Orai1 (show ORAI1 Antibodies) activation stemming from its enhanced sensitivity to store-depletion

  2. STIM2.1 cannot activate Orai1 (show ORAI1 Antibodies) due to splicing in residues within the channel-activating domain (CAD (show CAD Antibodies)). STIM2.1 confers a calcium dependent dominant-negative function on both STIM1 (show STIM1 Antibodies) and STIM2 (STIM2.2). Affinity of the STIM2.1 calmodulin (show CALM1 Antibodies) binding site within the CAD (show CAD Antibodies) domain is increased compared to STIM2.2.

  3. STIM2 enhances receptor-stimulated Ca(2 (show CA2 Antibodies)) signaling by promoting recruitment of STIM1 (show STIM1 Antibodies) to the endoplasmic reticulum-plasma membrane junctions.

  4. STIM2beta does not by itself strongly bind Orai1 (show ORAI1 Antibodies), it is recruited to Orai1 (show ORAI1 Antibodies) channels by forming heterodimers with other STIM isoforms.

  5. Imin channels are regulated by STIM2, TRPC3 (show TRPC3 Antibodies)-containing INS (show INS Antibodies) channels are induced by STIM1 (show STIM1 Antibodies), and TRPC1 (show TRPC1 Antibodies)-composed Imax channels are activated by both STIM1 (show STIM1 Antibodies) and STIM2.

  6. The higher amplitude of store-operated Ca2 (show CA2 Antibodies)+ entry was associated to the over-expression for Stim2, Orai2 (show ORAI2 Antibodies)-3, and TRPC1 (show TRPC1 Antibodies) while Stim2 levels remained constant and Stim1 (show STIM1 Antibodies), Orai1 (show ORAI1 Antibodies), Orai3 (show ORAI3 Antibodies), TRPC1 (show TRPC1 Antibodies) and TRPC4 (show TRPC4 Antibodies) proteins were over-expressed in primary myelofibrosis.

  7. the reciprocal shift in transient receptor potential channel 1 (TRPC1 (show TRPC1 Antibodies)) and stromal interaction molecule 2 (STIM2) contributes to Ca2 (show CA2 Antibodies)+ remodeling and cancer hallmarks in colorectal carcinoma cells

  8. STIM2 is highly expressed and controls store-operated Ca(2 (show CA2 Antibodies)+) entry in human melanoma. The invasive and migratory potential of melanoma cells was reduced upon silencing of STIM2.

  9. Binding of the lysine rich domains of STIM1 (show STIM1 Antibodies) and STIM2 to phosphatidylinositol 4,5 biphosphate rich liposomes depends on their oligomerization.

  10. STIM2 is involved in spatial l (show STIM1 Antibodies)earning and plays an important rol (show CA2 Antibodies)e in ischemic-induced neuronal cell death du (show CA2 Antibodies)ring brain hypoxia. The absence of STIM2 reduces life expectancy in mice by sudden death.

Mouse (Murine) Stromal Interaction Molecule 2 (Stim2) interaction partners

  1. Expression of STIM2 protein rescued CaMKII (show CAMK2G Antibodies) activity and protected mushroom spines from Abeta42 oligomer toxicity in vitro and in vivo.

  2. SOCE blockers or ablation of STIM1 (show STIM1 Antibodies), STIM2, or Orai1 (show TMEM132A Antibodies) severely impaired nucleotide-induced migration and phagocytosis in microglia.

  3. The data from this study indicate that upregulation of STIM2 and Orai2 (show ORAI2 Antibodies) is involved in the phenotypic transition of pulmonary arterial smooth muscle cells from a contractile state to a proliferative state.

  4. STIM1 (show STIM1 Antibodies), STIM2, and CRAC channel function play distinct but synergistic roles in CD4 (show CD4 Antibodies)+ and CD8 (show CD8A Antibodies)+ T cells during antiviral immunity

  5. STIM2 deficiency significantly delays onset and attenuates the clinical course of experimental allergic encephalitis.

  6. Using mice lacking STIM1 (show STIM1 Antibodies) and its homologue STIM2, authors find that store-operated calcium entry in CD8 (show CD8A Antibodies)(+) T cells is required to prevent the engraftment of melanoma and colon carcinoma cells and to control tumour growth.

  7. STIM1 (show STIM1 Antibodies) and STIM2-mediated store-operated Ca2 (show CA2 Antibodies)+ influx, leading to efficient activation of NFAT (show NFATC1 Antibodies) (nuclear factor of activated T cells), is critical for the postselection maturation of agonist-selected T cells.

  8. STIM1 (show STIM1 Antibodies) and STIM2 protein deficiency in T lymphocytes underlies development of the exocrine gland autoimmune disease, Sjogren's syndrome.

  9. show that endoplasmic reticulum calcium sensors STIM1 (show STIM1 Antibodies)- and STIM2-induced store-operated Ca(2 (show CA2 Antibodies)+) influx is critical for B cell regulatory function

  10. Absence of STIM2 in mouse embryonic fibroblasts results in a decreased store-operated calcium ion entry, although this inhibition is less pronounced than for STIM1 (show STIM1 Antibodies).

Stim2 Antigen Profile

Protein Summary

This gene is a member of the stromal interaction molecule (STIM) family and likely arose, along with related family member STIM1, from a common ancestral gene. The encoded protein functions to regulate calcium concentrations in the cytosol and endoplasmic reticulum, and is involved in the activation of plasma membrane Orai Ca(2+) entry channels. This gene initiates translation from a non-AUG (UUG) start site. A signal peptide is cleaved from the resulting protein. Multiple transcript variants result from alternative splicing.

Gene names and symbols associated with Stim2

  • stromal interaction molecule 2 (STIM2) antibody
  • stromal interaction molecule 2 (stim2) antibody
  • stromal interaction molecule 2 (Stim2) antibody
  • STIM2 antibody

Protein level used designations for Stim2

stromal interaction molecule 2

GENE ID SPECIES
100083707 Ornithorhynchus anatinus
100471703 Ailuropoda melanoleuca
100566248 Anolis carolinensis
422799 Gallus gallus
461155 Pan troglodytes
541299 Bos taurus
694980 Macaca mulatta
733739 Xenopus (Silurana) tropicalis
100540015 Meleagris gallopavo
57620 Homo sapiens
116873 Mus musculus
117087 Rattus norvegicus
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