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Stim2 antibody (C-Term)

Stim2 Reactivity: Human, Mouse, Rat WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN500829
  • Target See all Stim2 Antibodies
    Stim2 (Stromal Interaction Molecule 2 (Stim2))
    Binding Specificity
    • 10
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 37
    • 13
    • 8
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 35
    • 1
    • 1
    Rabbit
    Clonality
    • 37
    Polyclonal
    Conjugate
    • 21
    • 5
    • 4
    • 3
    • 2
    • 2
    This Stim2 antibody is un-conjugated
    Application
    • 33
    • 27
    • 19
    • 4
    • 4
    • 4
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects STIM2 at C-term). It is predicted to have no cross-reactivity to STIM1.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Peptide affinity chromatography
    Immunogen
    STIM2 antibody was raised against a 18 amino acid peptide from near the carboxy terminus of human STIM2.
    Isotype
    IgG
    Top Product
    Discover our top product Stim2 Primary Antibody
  • Application Notes
    ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    Stim2 (Stromal Interaction Molecule 2 (Stim2))
    Alternative Name
    STIM2 (Stim2 Products)
    Synonyms
    STIM2 antibody, stromal interaction molecule 2 antibody, STIM2 antibody, stim2 antibody, Stim2 antibody
    Background
    In T lymphocytes, the sole pathway for Ca++ entry following antigen-receptor binding is through store-operated Ca++-release-activated Ca++ (CRAC) channels. These channels are made up of the pore-forming subunit ORAI1 and the stromal interaction molecule 1 (STIM1), a protein that functions as a Ca++ sensor and activates the CRAC channels, migrating to the plasma membrane from endoplasmic reticulum (ER)-like sites which act as the Ca++ store. A related molecule, STIM2, acts to inhibit the STIM1-mediated store-operated Ca++ entry, and can form complexes with STIM1, suggesting they may play a coordinated role in controlling Ca++ entry. At least three isoforms of STIM2 are known to exist.Synonyms: KIAA1482, Stromal interaction molecule 2
    Gene ID
    57620
    NCBI Accession
    NP_065911
    Pathways
    TCR Signaling, BCR Signaling
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