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The protein encoded by THBS1 is a subunit of a disulfide-linked homotrimeric protein. Additionally we are shipping Thrombospondin 1 Antibodies (175) and Thrombospondin 1 Proteins (28) and many more products for this protein.
Showing 10 out of 48 products:
Mouse (Murine) Thrombospondin 1 ELISA Kit for Sandwich ELISA - ABIN415440
Kang, Lim, Lee, Yeo, Kang: Anthocyanin-rich purple corn extract inhibit diabetes-associated glomerular angiogenesis. in PLoS ONE 2013
Rat (Rattus) Thrombospondin 1 ELISA Kit for Sandwich ELISA - ABIN416163
Garcia-Diaz, Arellano, Milagro, Moreno-Aliaga, Portillo, Martinez, Campion: Glucose and insulin modify thrombospondin 1 expression and secretion in primary adipocytes from diet-induced obese rats. in Journal of physiology and biochemistry 2011
ELL (show ELL ELISA Kits) (Eleven-Nineteen Lysine-rich Leukemia) acts as a transcription factor for direct thrombospondin-1 regulation
quercetin could increase TSP-1 expression to inhibit angiogenesis resulting in antagonizing prostate cancer PC-3 (show PCSK1 ELISA Kits) cell and xenograft tumor growth
The anti-angiogenic activity of the native TSP-1 active fragment was maintained in the new TSP-1 mimetics and the results provide a new chemical approach for the design of TSP-1 mimetics.
In the current study Factor V Leiden (show F5 ELISA Kits), prothrombin (show F2 ELISA Kits) G20210A, and thrombospondin-1 polymorphisms showed no association with severity of hepatic fibrosis.
Triptolide can down regulates the expression of thrombospondin 1 and TGF-beta-1 (show TGFB1 ELISA Kits) in renal tubular cells. This plays a role in the pathogenesis of renal tubular fibrosis.
increased plasma thrombospondin-1 concentrations following ICH (show COL4a2 ELISA Kits) are independently associated with injury severity and short-term and long-term clinical outcomes
Novel role of TNFalpha (show TNF ELISA Kits) in inducing inflammatory stress response in human microvascular endothelial cells through Akt (show AKT1 ELISA Kits)- and P38 MAPK (show MAPK14 ELISA Kits)-mediated expression of TSP-1, independent of NFkappaB (show NFKB1 ELISA Kits) signaling.
Plasma thrombospondin-1 concentrations are elevated obviously and are highly associated with long-term outcome of ischemic stroke
TSP1 up regulation might be critically involved in the disease progression with rheumatoid arthritis.
The THBS1 N700S polymorphism was associated with coronary artery disease risk.
DLL4 (show DLL4 ELISA Kits)/Notch1 (show NOTCH1 ELISA Kits) and BMP9 (show GDF2 ELISA Kits) interdependent signaling induces endothelial cell quiescence via P27KIP1 (show CDKN1B ELISA Kits)/thrombospondin pathway.
Data suggest THBS1 expression predominates in luteal endothelial cells; THBS2 (show THBS2 ELISA Kits) expression predominates in luteinized granulosa cells. Luteinization down-regulates expression of THBS1/THBS2 (show THBS2 ELISA Kits), up-regulates expression of FGF2 (fibroblast growth factor 2 (show FGF2 ELISA Kits)).
Thrombospondin has a role in inducing RhoA (show RHOA ELISA Kits) inactivation through FAK (show PTK2 ELISA Kits)-dependent signaling to stimulate focal adhesion disassembly
Thrombospondin-1 and -2 were coordinately expressed in the extravascular compartment of the ovary during early follicle development. VEGF was inversely expressed, with expression increasing as follicles developed.
Preincubation of erythroid cells with thrombospondin 1 eliminated the inhibitory activity of insulin (show INS ELISA Kits)-like growth factor
The cell-specific regulation of TSP-1 suggests a potential mechanism for the aberrant angiogenesis in diabetics and TSP-1 involvement in development of various vascular diabetic complications
The novel finding that TSP-1-induced migration is dependent on the CD44 (show CD44 ELISA Kits) receptor links 2 pathways thought to be disparate (ie, TSP-1 and HyA (show KDM5D ELISA Kits)).
demonstrate that HIF-2alpha (show EPAS1 ELISA Kits) is clearly implicated in the TSP1 (show GZMA ELISA Kits) pulmonary regulation and provide new insights on its contribution to pulmonary arterial hypertension-driven vascular remodelling and vasoconstriction
Thrombospondin-1 was differentially expressed according to tumor grade, but not affected by p53 (show TP53 ELISA Kits) expression or mutational status
Data suggest neutrophil protease- Tsp-1 (thrombospondin-1) axis as a potential antimetastatic therapeutic target.
These results contribute new insights on the controversial role of TSP-1 (show GZMA ELISA Kits) in cancer.
TSP1 (show GZMA ELISA Kits) contributes to progression of chronic kidney disease by catalyzing activation of latent TGF-beta1 (show TGFB1 ELISA Kits), resulting in promotion of a fibroproliferative response over an inflammatory response.
Thrombospondin1 deficiency did not affect the development of obesity associated macro-vascular complication in ApoE (show APOE ELISA Kits)-/- mice, but attenuated obesity associated micro-vascular complications.
Thrombospondin-1 expression plays a significant role in regulation of migration and adhesion of mononuclear cells, contributing to vascular inflammation during AAA (show AAAS ELISA Kits) development.
findings prove that the TSP-1 (show GZMA ELISA Kits)/CD47 (show CD47 ELISA Kits)/SIRP (show SIRPA ELISA Kits)-alpha signal axis is important to the evolution of tumor cells in the microenvironment of immunotherapy and identify thrombospondin-1 as a key signal
ADAMTS-7 (show ADAMTS7 ELISA Kits) was directly associated with thrombospondin-1 by its C terminus and degraded thrombospondin-1 in vivo and in vitro. The inhibitory effect of ADAMTS-7 (show ADAMTS7 ELISA Kits) on postinjury endothelium recovery was circumvented in Tsp1 (show GZMA ELISA Kits)(-/-) mice.
Thrombospondin-1 and CD47 (show CD47 ELISA Kits) signaling regulate healing of thermal injury in mice.
These current studies were undertaken to determine how TSP-1 functions to modulate the smooth muscle cell response to IGF-I (show IGF1 ELISA Kits) and the mechanisms by which hyperglycemia regulates TSP-1 protein.
Increased TSP-1 expression in non-heart-beating donors may indicate a compensatory response to the reported diminished TGF-beta1 (show TGFB1 ELISA Kits) expression.
The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis.
, cancer/testis antigen 36
, glyceraldehyde-3-phosphate dehydrogenase-like 5
, testis specific protein 1 (probe H4-1 p3-1)
, testis-specific protein TPX-1