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WFDC2 encodes a protein that is a member of the WFDC domain family. Additionally we are shipping WFDC2 Proteins (21) and WFDC2 Kits (14) and many more products for this protein.
Showing 10 out of 141 products:
Human Monoclonal WFDC2 Primary Antibody for ELISA, WB - ABIN396057
Hellstrom, Heagerty, Swisher, Liu, Jaffar, Agnew, Hellstrom: Detection of the HE4 protein in urine as a biomarker for ovarian neoplasms. in Cancer letters 2010
Show all 5 references for ABIN396057
Human Polyclonal WFDC2 Primary Antibody for DB, EIA - ABIN492984
Galgano, Hampton, Frierson: Comprehensive analysis of HE4 expression in normal and malignant human tissues. in Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2006
Show all 4 references for ABIN492984
Human Polyclonal WFDC2 Primary Antibody for DB, EIA - ABIN2712091
Alberti, Bachelot, Duc, Biota, Blay: A spliced isoform of interleukin 6 mRNA produced by renal cell carcinoma encodes for an interleukin 6 inhibitor. in Cancer research 2005
Show all 4 references for ABIN2712091
Dog (Canine) Polyclonal WFDC2 Primary Antibody for EIA, WB - ABIN569663
Huhtinen, Suvitie, Hiissa, Junnila, Huvila, Kujari, Setälä, Härkki, Jalkanen, Fraser, Mäkinen, Auranen, Poutanen, Perheentupa: Serum HE4 concentration differentiates malignant ovarian tumours from ovarian endometriotic cysts. in British journal of cancer 2009
Human Monoclonal WFDC2 Primary Antibody for ELISA, WB - ABIN564522
Yuan, Duan, Yang, Luo, Xi: Detection of serum human epididymis secretory protein 4 in patients with ovarian cancer using a label-free biosensor based on localized surface plasmon resonance. in International journal of nanomedicine 2012
optimal cut-off values (HE4: 70pmol/l for all; CA125 (show MUC16 Antibodies): 60U/ml for pre- and 35U/ml for postmenopausal women) could notably improve diagnostic performance in EOC detection in patients in southern China
Results show that recombinant HE4 proteins are able to promote the proliferation of pancreatic and endometrial cancer cells suggesting that HE4 secreted from cancer cells may carry out paracrine and endocrine functions in cancer patients.
Increased WFDC2 expression plays an important role in altering the estrogen pathway in ovarian cancer.
Endometrial cancer patients with high HE4 expression have a poor prognosis.
Data show that serum neuron-specific enolase (show ENO2 Antibodies), cytokeratin 19 (show KRT19 Antibodies) fragment 21-1, pro-gastrin-releasing peptide (show GRP Antibodies), squamous cell carcinoma antigen, tissue inhibitor of metalloproteinase-1, and human epididymis protein 4 are not associated with brain metastases.
In this report, we describe our use of capillary electrophoresis (CE) as the separation mechanism in the process of selecting DNA aptamers with affinity for the ovarian cancer biomarker HE4.
Expression levels of ANXA2 (show ANXA2 Antibodies) and HE4 were closely related to the malignant biological behavior of endometrial carcinoma
High serum HE4 level at diagnosis is an independent determinant of poor prognosis in NSCLC.
Authors examined the serum concentration of human epididymis protein (HE4) in patients with benign gynecological diseases complicated with chronic renal deficiency
Body mass index does not influence HE4 levels in serum.
Causal testing implicates Wfdc2 and Hdac3 (show HDAC3 Antibodies) as novel genes affecting high density lipoprotein levels
This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation.
WAP four-disulfide core domain 2
, WAP four-disulfide core domain 3
, WAP four-disulfide core domain protein 2
, WAP domain containing protein HE4-V4
, epididymal protein 4
, epididymal secretory protein E4
, epididymis-specific, whey-acidic protein type, four-disulfide core
, major epididymis-specific protein E4
, putative protease inhibitor WAP5
, WAP domain-containing protein HE4
, epididymal secretory protein 4
, epididymal protein BE-20