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anti-WD Repeat and FYVE Domain Containing 3 (WDFY3) Antibodies

WDFY3 encodes a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for aggregate clearance by autophagy. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
WDFY3 23001 Q8IZQ1
WDFY3 72145 Q6VNB8
WDFY3 305164  
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Top anti-WDFY3 Antibodies at antibodies-online.com

Showing 10 out of 32 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-WDFY3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: Human Muscle 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-WDFY3 Antibody Titration: 0.2-1 ug/mlPositive Control: Human brain 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged WDFY3 is 0.3 ng/ml as a capture antibody. Western Blot detection against Immunogen (71.94 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB WDFY3 antibody used at 0.2-1 ug/ml to detect target protein. 50 μg Log in to see 7 to 9 Days
$473.93
Details
Human Rabbit Un-conjugated WB WDFY3 antibody used at 0.2-1 ug/ml to detect target protein. 50 μg Log in to see 7 to 9 Days
$473.93
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

WDFY3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-WDFY3 Antibodies

  1. Cow (Bovine) Polyclonal WDFY3 Primary Antibody for WB - ABIN2784357 : Hillier, Graves, Fulton, Fulton, Pepin, Minx, Wagner-McPherson, Layman, Wylie, Sekhon, Becker, Fewell, Delehaunty, Miner, Nash, Kremitzki, Oddy, Du, Sun, Bradshaw-Cordum, Ali, Carter, Cordes, Harris et al.: Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ... in Nature 2005 (PubMed)

  2. Human Monoclonal WDFY3 Primary Antibody for ELISA, WB - ABIN949075 : Orosco, Ross, Cates, Scott, Wu, Sohn, Pleasure, Pleasure, Adamopoulos, Zarbalis: Loss of Wdfy3 in mice alters cerebral cortical neurogenesis reflecting aspects of the autism pathology. in Nature communications 2014 (PubMed)

More Antibodies against WDFY3 Interaction Partners

Human WD Repeat and FYVE Domain Containing 3 (WDFY3) interaction partners

  1. we demonstrate that normally ALFY attenuates the canonical Wnt (show WNT2 Antibodies) signaling pathway via autophagy-dependent removal specifically of aggregates of DVL3 (show DVL3 Antibodies) and not of Dvl1 (show DVL1 Antibodies) or Dvl2 (show DVL2 Antibodies).

  2. ALFY binds selectively to LC3C (show MAP1LC3C Antibodies) and the GABARAPs through a LC3 (show MAP1LC3A Antibodies)-interacting region in its WD40 domain (show DCAF12L2 Antibodies).

  3. increasing Alfy-mediated protein degradation may be beneficial in some organs, but may be detrimental in others

  4. Data suggest that p62 (show GTF2H1 Antibodies) and ALFY interact to organize misfolded, ubiquitinated proteins into protein bodies that become degraded by autophagy.

  5. The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy.

  6. Alfy might target cytosolic protein aggregates for autophagic degradation.

Mouse (Murine) WD Repeat and FYVE Domain Containing 3 (WDFY3) interaction partners

  1. Alfy translocalization likely is involved in the pathogenesis of amyotrophic lateral sclerosis.

  2. Wdfy3 is important in regulating neural progenitor divisions, neural migration, cerebral expansion and functional organization in the developing brain. Loss-of-function leads to pathological changes characteristic of autism spectrum disorders.

  3. gene expression profiling; in situ hybridization analysis revealed that the expressed BWF1 mRNA was restricted to the marginal region both in E14 (show NPAT Antibodies) and E16 (show SLC7A5 Antibodies) embryonic brain, but became diffuse after birth

WDFY3 Antigen Profile

Protein Summary

This gene encodes a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for aggregate clearance by autophagy. This protein shuttles from the nuclear membrane to colocalize with aggregated proteins, where it complexes with other autophagic components to achieve macroautophagy-mediated clearance of these aggregated proteins. However, it is not necessary for starvation-induced macroautophagy.

Gene names and symbols associated with WDFY3

  • WD repeat and FYVE domain containing 3 (WDFY3) antibody
  • WD repeat and FYVE domain-containing protein 3 (MGYG_03998) antibody
  • WD repeat and FYVE domain containing 3 (Wdfy3) antibody
  • 2610509D04Rik antibody
  • ALFY antibody
  • AW319683 antibody
  • B930017C24 antibody
  • Bchs antibody
  • BWF1 antibody
  • D5Ertd66e antibody
  • Ggtb3 antibody
  • mKIAA0993 antibody
  • ZFYVE25 antibody

Protein level used designations for WDFY3

WD repeat and FYVE domain containing 3 , WD repeat and FYVE domain-containing protein 3 , autophagy-linked FYVE protein , beach domain, WD repeat and FYVE domain-containing protein 1 , galactosyltransferase 3 beta 1, 4

GENE ID SPECIES
100157904 Sus scrofa
461201 Pan troglodytes
10029110 Arthroderma gypseum CBS 118893
422613 Gallus gallus
23001 Homo sapiens
487841 Canis lupus familiaris
537096 Bos taurus
72145 Mus musculus
305164 Rattus norvegicus
Selected quality suppliers for anti-WDFY3 (WDFY3) Antibodies
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