WDFY3 antibody (Biotin)

Catalog No. ABIN1405471

This Rabbit Polyclonal antibody specifically detects WDFY3 in IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for WDFY3 antibody (Biotin) (ABIN1405471)

Target: WDFY3 (WD Repeat and FYVE Domain Containing 3 (WDFY3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDFY3 antibody is conjugated to Biotin

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-WDFY3 Antibody (Biotin)

Purpose: WDFY3 Polyclonal Antibody, Biotin Conjugated

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human WDFY3

Isotype: IgG

Application Details

Application Notes: IHC-P(IHC-P=1:100-500), IHC-F(IHC-F=1:100-500)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for WDFY3

Target: WDFY3 (WD Repeat and FYVE Domain Containing 3 (WDFY3))

Alternative Name: WDFY3

Background:

Synonyms: Alfy, Autophagy linked FYVE protein, KIAA0993, MGC16461, WD repeat and FYVE domain containing 3, ZFYVE25, WDFY3_HUMAN.

Background: WDFY3 was identified in a screen for phosphatidylinositol 3 phosphate binding proteins. The FYVE domain is a zinc binding domain found in many PtdIns binding proteins and is proposed to target proteins to membrane lipids. WDFY3 has been shown localized to the nuclear membrane and within autophagic membranes and it is proposed to function as a link between protein aggregates and the autophagic machinery. WDFY3 is also known as autophagy linked FYVE protein.

Gene ID: 23001