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anti-WNK Lysine Deficient Protein Kinase 1 (WNK1) Antibodies

WNK1 encodes a member of the WNK subfamily of serine/threonine protein kinases. Additionally we are shipping WNK1 Kits (4) and WNK1 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
WNK1 65125 Q9H4A3
WNK1 232341 P83741
WNK1 116477 Q9JIH7
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Top anti-WNK1 Antibodies at antibodies-online.com

Showing 10 out of 125 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from 293 cells treated with EGF 200ng/ml 30', using WNK1 (Phospho-Thr58) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using WNK1 (Phospho-Thr58) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from 293 cells, treated with EGF 200ng/ml 30', using WNK1 (Ab-58) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using WNK1 (Ab-58) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC (p) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC (p) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC (p) Anti-WNK1 antibody  ABIN1049464 IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA Human Skeletal Muscle (formalin-fixed, paraffin-embedded) stained with WNK1 antibody ABIN213554 at 4 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Gibbon Rabbit Un-conjugated IHC 0.05 mg Log in to see 2 to 3 Days
$481.25
Details
Bat Rabbit Un-conjugated IHC, ELISA 0.05 mg Log in to see 2 to 3 Days
$481.25
Details

WNK1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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More Antibodies against WNK1 Interaction Partners

Horse (Equine) WNK Lysine Deficient Protein Kinase 1 (WNK1) interaction partners

  1. HSN2 is a nervous system-specific exon of the WNK1 gene (WNK1/HSN2 isoform).

Chimpanzee WNK Lysine Deficient Protein Kinase 1 (WNK1) interaction partners

  1. HSN2 is a nervous system-specific exon of the WNK1 gene (WNK1/HSN2 isoform).

Xenopus laevis WNK Lysine Deficient Protein Kinase 1 (WNK1) interaction partners

  1. HSN2 is a nervous system-specific exon of the WNK1 gene (WNK1/HSN2 isoform).

Zebrafish WNK Lysine Deficient Protein Kinase 1 (WNK1) interaction partners

  1. wnk1 is a downstream target for Vegfr2 (vascular endothelial growth factor receptor-2 (show KDR Antibodies)) and Akt (show AKT1 Antibodies)/PI3K signaling and thereby affects angiogenesis in zebrafish embryos.

  2. loss-of-function mutation in WNK1 induces an overexpression of KCC2 (show SLC12A5 Antibodies) and hinders proper peripheral sensory nerve development, a hallmark of HSANII

Rhesus Monkey WNK Lysine Deficient Protein Kinase 1 (WNK1) interaction partners

  1. HSN2 is a nervous system-specific exon of the WNK1 gene (WNK1/HSN2 isoform).

Human WNK Lysine Deficient Protein Kinase 1 (WNK1) interaction partners

  1. Single nucleotide polymorphisms STK39 (show STK39 Antibodies) and WNK were associated with hypertension and BP in our multicenter Belgian case-control study

  2. these data provide insight into the mechanism regulating Cl(-) homeostasis in immature neurons, and suggest that WNK1-regulated changes in KCC2 (show SLC12A5 Antibodies) phosphorylation contribute to the developmental excitatory-to-inhibitory GABA sequence.

  3. Identify a new chimeric transcript generated by the fusion of WNK1 and B4GALNT3 genes, correlated with B4GALNT3 overexpression in papillary thyroid carcinoma.

  4. a novel gene, WNK1, for susceptibility to pelvic organ prolapse

  5. findings indicate that the proline-rich exons are modular cassettes that convert WNK1 into a NEDD4-2 (show NEDD4L Antibodies) substrate, thereby linking aldosterone and other NEDD4-2 (show NEDD4L Antibodies)-suppressing antinatriuretic hormones to NCC (show SLC12A3 Antibodies) phosphorylation status.

  6. enhances BK channel (show KCNMA1 Antibodies) function by reducing ERK1/2 (show MAPK1/3 Antibodies) signaling-mediated lysosomal degradation of the channel

  7. conclude that although multiple candidate genes are involved in development of hypertension, the genetic polymorphism in WNK1 is not a major contributor to the observed variability in blood pressure and familial clustering risk of hypertension

  8. study identifies a separation of functions for the WNK1-activated protein kinases OSR1 (show OXSR1 Antibodies) and SPAK (show STK39 Antibodies) in mediating proliferation, invasion, and gene expression in endothelial cells

  9. Report generation of WNK1 knockout cell lines and effects on WNK signaling.

  10. data suggest that WNK1 functions as a chloride sensor through direct binding of a regulatory chloride ion to the active site, which inhibits autophosphorylation

Mouse (Murine) WNK Lysine Deficient Protein Kinase 1 (WNK1) interaction partners

  1. A high-K(+) diet induced an increase in L-WNK1 expression selectively in intercalated cells and may contribute to enhanced BK channel (show KCNMA1 Antibodies) expression and K(+) secretion in collecting ducts.

  2. these data provide insight into the mechanism regulating Cl(-) homeostasis in immature neurons, and suggest that WNK1-regulated changes in KCC2 (show SLC12A5 Antibodies) phosphorylation contribute to the developmental excitatory-to-inhibitory GABA sequence.

  3. findings indicate that the proline-rich exons are modular cassettes that convert WNK1 into a NEDD4-2 (show NEDD4L Antibodies) substrate, thereby linking aldosterone and other NEDD4-2 (show NEDD4L Antibodies)-suppressing antinatriuretic hormones to NCC (show SLC12A3 Antibodies) phosphorylation status.

  4. enhances BK channel (show KCNMA1 Antibodies) function by reducing ERK1/2 (show MAPK1/3 Antibodies) signaling-mediated lysosomal degradation of the channel

  5. increased protein expression levels of WNK1 and WNK4 (show WNK4 Antibodies) kinases cause PHAII by KLHL3 (show KLHL3 Antibodies) R528H mutation due to impaired KLHL3 (show KLHL3 Antibodies)-Cullin3-mediated ubiquitination.

  6. study identifies a separation of functions for the WNK1-activated protein kinases OSR1 (show OSR1 Antibodies) and SPAK (show STK39 Antibodies) in mediating proliferation, invasion, and gene expression in endothelial cells

  7. WNK1 stimulates the activity of the Na-Cl cotransporter (show SLC12A3 Antibodies) via SPAK (show STK39 Antibodies), an effect antagonized by WNK4 (show WNK4 Antibodies).

  8. Results show that the expression profiles of Wnk1 isoforms change during the development, and that the expression of the Wnk1 splice variant containing the Hsn2 exon is prominent during developing and in adult mouse tissues.

  9. subset of integral membrane proteins, therefore, requires an early dislocation event to expose part of their luminal domain to the cytosol, before HRD1 (show SYVN1 Antibodies)-mediated polyubiquitination and dislocation

  10. In Wnk1 knockout mice, levels of Lhx8 (show LHX8 Antibodies) expression were reduced, inhibiting neural specification.

Pig (Porcine) WNK Lysine Deficient Protein Kinase 1 (WNK1) interaction partners

  1. HSN2 is a nervous system-specific exon of the WNK1 gene (WNK1/HSN2 isoform).

WNK1 Antigen Profile

Protein Summary

This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II. Alternatively spliced transcript variants encoding different isoforms have been described but the full-length nature of all of them has yet to be determined.

Gene names and symbols associated with WNK1

  • WNK lysine deficient protein kinase 1 (WNK1) antibody
  • WNK lysine deficient protein kinase 1 (wnk1.3) antibody
  • WNK lysine deficient protein kinase 1b (wnk1b) antibody
  • WNK lysine deficient protein kinase 1 (wnk1.2) antibody
  • WNK lysine deficient protein kinase 1 (wnk1) antibody
  • WNK lysine deficient protein kinase 1 (LOC100350906) antibody
  • serine/threonine-protein kinase WNK1 (WNK1) antibody
  • WNK lysine deficient protein kinase 1 (Wnk1) antibody
  • 6430573H23Rik antibody
  • ATWNK1 antibody
  • EG406236 antibody
  • fc14f06 antibody
  • HSAN2 antibody
  • Hsn2 antibody
  • KDP antibody
  • mKIAA0344 antibody
  • p65 antibody
  • pha2c antibody
  • Prkwnk1 antibody
  • PSK antibody
  • si:ch211-240l19.1 antibody
  • T9J14.14 antibody
  • T9J14_14 antibody
  • with no lysine (K) kinase 1 antibody
  • wnk1 antibody
  • wu:fc14f06 antibody
  • ZIK4 antibody

Protein level used designations for WNK1

WNK lysine deficient protein kinase 1 , serine/threonine-protein kinase WNK1-like , WNK lysine deficient protein kinase 1 isoform , erythrocyte 65 kDa protein , prostate-derived sterile 20-like kinase , protein kinase with no lysine 1 , serine/threonine-protein kinase WNK1 , protein kinase lysine-deficient 1

GENE ID SPECIES
100056745 Equus caballus
451739 Pan troglodytes
496095 Xenopus laevis
561159 Danio rerio
706493 Macaca mulatta
733420 Xenopus laevis
734160 Xenopus laevis
100017207 Monodelphis domestica
100036683 Xenopus (Silurana) tropicalis
100350906 Oryctolagus cuniculus
100436057 Pongo abelii
100594288 Nomascus leucogenys
819651 Arabidopsis thaliana
65125 Homo sapiens
232341 Mus musculus
116477 Rattus norvegicus
477728 Canis lupus familiaris
406235 Sus scrofa
506433 Bos taurus
427925 Gallus gallus
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