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anti-Zinc Finger Protein ZIC 1 (ZIC1) Antibodies

ZIC1 encodes a member of the ZIC family of C2H2-type zinc finger proteins. Additionally we are shipping ZIC1 Kits (9) and ZIC1 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ZIC1 7545 Q15915
ZIC1 64618  
ZIC1 22771 P46684
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Top anti-ZIC1 Antibodies at antibodies-online.com

Showing 10 out of 62 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB ZIC1 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35 µg/lane). This demonstrates the ZIC1 antibody detected the ZIC1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged ZIC1 is approximately 0.3 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-ZIC1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: ACHN cell lysate WB Suggested Anti-ZIC1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:12500  Positive Control: ACHN cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB ZIC1 Antibody (N-term)  western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the ZIC1 antibody detected the ZIC1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated ICC, IHC, WB 100 μg Log in to see 8 to 10 Days
$595.83
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Immunohistochemistry (IHC) analyzes of Zic1/2/3 antibody in paraffin-embedded human brain tissue. Western blot (WB) analysis of Zic1/2/3 antibody in extracts from Jurkat cells. 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (36.08 KDa) . 200 μL Log in to see 9 Days
$430.00
Details
Human Rabbit FITC ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details

ZIC1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-ZIC1 Antibodies

  1. Human Polyclonal ZIC1 Primary Antibody for EIA, WB - ABIN955670 : Brill, Gobble, Angeles, Lagos-Quintana, Crago, Laxa, Decarolis, Zhang, Antonescu, Socci, Taylor, Sander, Koff, Singer: ZIC1 overexpression is oncogenic in liposarcoma. in Cancer research 2010 (PubMed)
    Show all 5 references for ABIN955670

  2. Human Monoclonal ZIC1 Primary Antibody for ELISA, WB - ABIN394292 : Wang, Jin, Wang, Lam, Zhang, Liu, Chan, Si, Sung: ZIC1 is downregulated through promoter hypermethylation in gastric cancer. in Biochemical and biophysical research communications 2009 (PubMed)
    Show all 5 references for ABIN394292

More Antibodies against ZIC1 Interaction Partners

Human Zinc Finger Protein ZIC 1 (ZIC1) interaction partners

  1. down-regulated expression of ZIC1 contributed to the inhibition of cell proliferation, and inhibited the growth of tumor

  2. our results suggest that the Zic1 promoter methylation rate in plasma-derived DNA is of great significance for the early screening of gastric cancer and monitoring of tumorigenesis

  3. Gain-of-Function Mutations in ZIC1 Are Associated with Coronal Craniosynostosis and Learning Disability.

  4. ZIC1 might play a role in the development of Ovarian Cancer, and may be a therapeutic target in OC.

  5. aberrant methylation is an important mechanism for ZIC1 inactivation in Hepatocellular carcinoma (HCC (show FAM126A Antibodies)).

  6. ZIC1 is frequently inactivated by promoter hypermethyaltion and functions as a tumor suppressor in thyroid cancer through modulating PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) and MAPK (show MAPK1 Antibodies) signaling pathways and transcription factor FOXO3a (show FOXO3 Antibodies).

  7. Loss of ZIC1 expression is associated with malignant pleural mesothelioma.

  8. Methylation of ZIC1, a putative tumor suppressor, may be a novel determinant of ovarian cancer outcome

  9. Zic transcription factors function in patterning hindbrain motor neurons through their regulation of embryonic retinoic acid signaling

  10. Overexpression of ZIC1 results in inactivation of Shh (show SHH Antibodies), PI(3 (show PI3 Antibodies))K and MAPK (show MAPK1 Antibodies) signaling pathways, as well as regulation of multiple downstream targets which are essential for the development and progression of gastric cancer.

Xenopus laevis Zinc Finger Protein ZIC 1 (ZIC1) interaction partners

  1. Zic1 (show ZIC5 Antibodies), expressed at the anterior neural plate, is necessary and sufficient to promote placode fate.

  2. Pax3 (show PAX3 Antibodies) and Zic1 (show ZIC5 Antibodies) trigger the early neural crest gene regulatory network by the direct activation of multiple key neural crest specifiers.

  3. Pax3 (show PAX3 Antibodies) and Zic1 (show ZIC5 Antibodies) drive induction and differentiation of multipotent, migratory, and functional neural crest in Xenopus embryos.

  4. XMeis3 (show MEIS3 Antibodies) protein knock down also causes a loss of primary neuron and neural crest cell lineages, without altering expression of Zic, Sox (show PIPOX Antibodies) or Pax3 (show PAX3 Antibodies) genes.

  5. Co-activation of Pax3 (show PAX3 Antibodies) and Zic1 (show ZIC5 Antibodies), in concert with Wnt (show WNT2 Antibodies), plays a decisive role for early neural crest determination in the correct place of the Xenopus ectoderm.

  6. These data suggest that interruption of BMP signaling facilitates neural determination via a complex mechanism, involving multiple regulatory factors that cooperate to control zic1 (show ZIC5 Antibodies) expression

  7. Zic1 (show ZIC5 Antibodies) directly upregulated the Xfeb gene during early neural development.

  8. Zic1 (show ZIC5 Antibodies) is an activator of Wnt (show WNT2 Antibodies) signaling.

  9. Data show that Pax3 (show PAX3 Antibodies) and Zic1 (show ZIC5 Antibodies) are necessary and sufficient to promote hatching gland and preplacodal fates, respectively, and that their combined activity is essential to specify the neural crest.

  10. aqp-3b was upregulated by Zic1 (show ZIC5 Antibodies)

Mouse (Murine) Zinc Finger Protein ZIC 1 (ZIC1) interaction partners

  1. Brn2 (show POU3F2 Antibodies)-Zic1 axis is essential to specify neural fate in retinoic-acid-treated embryonic stem cells.

  2. Zic1 and Zic2 (show ZIC2 Antibodies) are required for coordinating mature neuronal gene expression patterns.

  3. Association with DNA-bound Pax3 (show PAX3 Antibodies) strengthens the ability of both Zic1 and Gli2 (show GLI2 Antibodies) to transactivate Myf5 (show MYF5 Antibodies) in the epaxial somite.

  4. Zic1 and Zic4 (show ZIC4 Antibodies) have both Shh (show SHH Antibodies)-dependent and -independent roles during cerebellar development and multiple developmental disruptions underlie Zic1/4-related Dandy-walker malformation.

  5. Myf5 (show MYF5 Antibodies) activation in newly forming somites is delayed in Zic2 (show ZIC2 Antibodies) mutant embryos until the time of Zic1 activation, and both Zic2 (show ZIC2 Antibodies) and Myf5 (show MYF5 Antibodies) require noggin (show NOG Antibodies) for their activation

  6. Zic1, a neural developmental transcription factor, plays an important role in shear flow mechanotransduction in osteocytes.

  7. findings suggest that Zic1 controls the expansion of neuronal precursors by inhibiting the progression of neuronal differentiation

  8. The functions of Zic1 and Zic3 (show ZIC3 Antibodies) may be essential to increasing neural cell numbers regionally in the medial telencephalon and to proper mediolateral patterning of the telencephalon.

  9. This study reveal a new role for Zic1 as a cell-autonomous regulator of key aspects of nucleus formation and axon pathway choice in the ventral brain stem.

ZIC1 Antigen Profile

Protein Summary

This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development. Aberrant expression of this gene is seen in medulloblastoma, a childhood brain tumor. This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 4, a related family member on chromosome 3. This gene encodes a transcription factor that can bind and transactivate the apolipoprotein E gene.

Gene names and symbols associated with ZIC1

  • Zic family member 1 (ZIC1) antibody
  • Zic family member 1 (Zic1) antibody
  • Zic family member 1 (zic1) antibody
  • zinc finger protein of the cerebellum 1 (Zic1) antibody
  • opl antibody
  • ZIC antibody
  • ZNF201 antibody

Protein level used designations for ZIC1

Zic family member 1 (odd-paired homolog, Drosophila) , Zinc finger protein of the cerebellum 1 , zinc finger protein 201 , zinc finger protein ZIC 1 , zic protein member 1 , zinc finger protein of the cerebellum 1 , XZic1 , ZIC-r1 , ZIC-related protein 1 , Zic family member 1 (odd-paired homolog) , Zic-related-1 , xlZic1 , xopl , odd-paired homolog

GENE ID SPECIES
7545 Homo sapiens
64618 Rattus norvegicus
374103 Gallus gallus
399124 Xenopus laevis
22771 Mus musculus
Selected quality suppliers for anti-ZIC1 (ZIC1) Antibodies
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