Browse our MICA Proteins (MICA)

Full name:
MHC Class I Polypeptide-Related Sequence A Proteins (MICA)
On are 18 MHC Class I Polypeptide-Related Sequence A (MICA) Proteins from 8 different suppliers available. Additionally we are shipping MICA Antibodies (152) and MICA Kits (31) and many more products for this protein. A total of 213 MICA products are currently listed.
FLJ60820, Ica, MGC111087, MIC-A, mICA, PERB11.1
list all proteins Gene Name GeneID UniProt
Mouse MICA MICA 71775 Q9DBD0
MICA 4276  

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MICA Proteins (MICA) by Origin

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Top referenced MICA Proteins

  1. Human MICA Protein expressed in HEK-293 Cells - ABIN2181502 : Groh, Steinle, Bauer, Spies: Recognition of stress-induced MHC molecules by intestinal epithelial gammadelta T cells. in Science (New York, N.Y.) 1998 (PubMed)
    Show all 3 references for 2181502

  2. Human MICA Protein expressed in Human Cells - ABIN2005167 : Xiang, Liu, Zheng, Liu, Lv, Gao, Hu, Lam, Chan, Yang, Chen, Tsao, Bonneville, Lau, Tu: Targeted activation of human V?9V?2-T cells controls epstein-barr virus-induced B cell lymphoproliferative disease. in Cancer cell 2014 (PubMed)
    Show all 2 references for 2005167

More Proteins for MICA Interaction Partners

Mouse (Murine) MHC Class I Polypeptide-Related Sequence A (MICA) interaction partners

  1. Murine inhibitor of carbonic anhydrase was a glycoprotein that associated with carbonic anhydrase in a 1:1 stoichiometry.[ICA]

Human MHC Class I Polypeptide-Related Sequence A (MICA) interaction partners

  1. New truncated MICA isoforms exhibit a range of functions that may drive unexpected immune mechanisms and provide new tools for immunotherapy

  2. data reveal that MICA and PVR (show PVR Proteins) are directly regulated by human cytomegalovirus immediate early (show JUN Proteins) proteins, and this may be crucial for the onset of an early host antiviral response

  3. This demonstrates for the first time that MICA/B is more broadly expressed in normal tissue and that expression is mainly intracellular with only a small fraction appearing on the cell surface of some epithelia and tumour cells.

  4. selecting a MICA-matched donor significantly influences key clinical outcomes of HCT in which a marked reduction of GVHD is paramount. The tight linkage disequilibrium between MICA and HLA-B renders identifying a MICA-matched donor readily feasible in clinical practice.

  5. MICA-129 matching is relevant in unrelated hematopoietic stem cell transplantation.

  6. No evidence of an association between MICA*Del and nasopharyngeal carcinoma in the southern Chinese Han population.

  7. These findings identify the major histocompatibility complex-related MICA as an immunogenetic factor that may functionally influence anti-BK polyomavirus immune responses and infection outcomes.

  8. This study provided information on the distribution of MICA polymorphisms and linkage disequilibrium with HLA-B alleles in Brazilian renal-transplant candidates. A total of 19 MICA allele groups were identified. The most frequent allele groups were MICA*008 (21.6%), MICA*002 (17.0%) and MICA*004 (14.8%). The most common haplotypes were MICA*009-B*51 (7.8%), MICA*004-B*44 (6.06%) and MICA*002-B*35 (5.63%).

  9. MICA*A4 protects against ulcerative colitis, whereas MICA*A5.1 is associated with abscess formation and age of onset.

  10. MICA*012:05 differs from MICA*012:01 by a single synonymous C to T substitution at nucleotide position 269 in exon

MICA Protein Profile

Protein Summary

MICA encodes the higly polymorphic MHC (HLA) class I chain-related gene A. The protein product is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with MICA

  • RIKEN cDNA 1300017J02 gene (1300017J02Rik)
  • MHC class I polypeptide-related sequence A (MICA)
  • FLJ60820 protein
  • Ica protein
  • MGC111087 protein
  • MIC-A protein
  • mICA protein
  • PERB11.1 protein

Protein level used designations for MICA

inhibitor of carbonic anhydrase , MHC class I polypeptide-related sequence A , HLA class I antigen , Stress inducible class I homolog , MHC class I chain-related protein A , MHC class I chain-related gene A protein , stress inducible class I homolog , F10 alpha chain-like , class I histocompatibility antigen

71775 Mus musculus
4276 Homo sapiens
100507436 Homo sapiens
417067 Gallus gallus
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