Browse our PRKAB2 Proteins (PRKAB2)

On are 9 Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) Proteins from 6 different suppliers available. Additionally we are shipping PRKAB2 Antibodies (67) and many more products for this protein. A total of 78 PRKAB2 products are currently listed.
5730553K21Rik, AW049591, BB124140, DKFZp469M1118, MGC64365, PRKAB2
list all proteins Gene Name GeneID UniProt
PRKAB2 5565 O43741
PRKAB2 108097 Q6PAM0
PRKAB2 64562 Q9QZH4

PRKAB2 Proteins (PRKAB2) by Origin

More Proteins for PRKAB2 Interaction Partners

Human Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) interaction partners

  1. Sumoylation of AMPKbeta2 subunit enhances AMP-activated protein kinase (show PRKAA2 Proteins) activity.

  2. Data indicate that except AMPK (show PRKAA1 Proteins)-alpha1, expressions of the other five AMPK (show PRKAA1 Proteins) subunits -alpha2, -beta1, -beta2, -gamma1 and -gamma2 are significantly higher in ovarian carcinomas.

  3. Studies suggest insights into the regulation of AMPK (show PRKAA1 Proteins), its diverse biological actions, and therapeutic potential in the heart.

  4. results of this study demonistrated that the novel findings that intronic SNPs in the genes coding for the regulatory beta2(PRKAB2) of AMPK (show PRKAA1 Proteins) are associated with antipsychotic-induced weight gain in schizophrenia or schizoaffective disorder patients

  5. These results suggest that the modification introduced by the laforin (show EPM2A Proteins)-malin (show NHLRC1 Proteins) complex could affect the subcellular distribution of AMPK (show PRKAA1 Proteins) beta subunits.

  6. Purification and characterization of truncated human AMPK alpha 2 (show PRKAA2 Proteins) beta 2 gamma 3 heterotrimer from baculovirus-infected insect cells

  7. variants in PRKAB2 are unlikely to contribute to the type 2 diabetes mellitus susceptibility in Pima Indians

Mouse (Murine) Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) interaction partners

  1. AMPK (show PRKAA1 Proteins) directly relaxes vascular smooth muscle cell by a decrease of [Ca(2 (show CA2 Proteins)+)]i. This is achieved by calcium sequestration via SERCA (show ATP2A3 Proteins) activation, as well as activation of BKCa (show KCNMA1 Proteins) channels.

  2. AMPK (show PRKAA1 Proteins) beta1beta2 have a role in preventing myopathy due to loss of capillary density in nonpostural muscles

  3. The beta2 subunit plays an important role in regulating glucose, glycogen (show GYS1 Proteins), and lipid metabolism during metabolic stress. beta2 mutant animals failed to maintain euglycemia and muscle ATP levels during fasting.

  4. Deletion of AMPK (show PRKAA1 Proteins) beta2 reduces AMPK (show PRKAA1 Proteins) activity in skeletal muscle resulting in impaired exercise capacity.

  5. Germline deletion of either AMPK (show PRKAA1 Proteins) beta1 or beta2 subunit isoforms resulted in reduced trabecular bone density and mass, but without effects on osteoclast (OC) or osteoblast (OB) numbers.

  6. Results suggest that p38 MAPK (show MAPK14 Proteins) is not a downstream component of AMPK (show PRKAA1 Proteins)-mediated signaling in skeletal muscle.

PRKAB2 Protein Profile

Protein Summary

The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles.

Alternative names and synonyms associated with PRKAB2

  • protein kinase, AMP-activated, beta 2 non-catalytic subunit (prkab2)
  • protein kinase, AMP-activated, beta 2 non-catalytic subunit (PRKAB2)
  • protein kinase, AMP-activated, beta 2 non-catalytic subunit (LOC100218045)
  • protein kinase, AMP-activated, beta 2 non-catalytic subunit (Prkab2)
  • 5730553K21Rik protein
  • AW049591 protein
  • BB124140 protein
  • DKFZp469M1118 protein
  • MGC64365 protein
  • PRKAB2 protein

Protein level used designations for PRKAB2

protein kinase, AMP-activated, beta 2 non-catalytic subunit , AMP-activated protein kinase beta 2 non-catalytic subunit , 5'-AMP-activated protein kinase subunit beta-2 , 5'-AMP-activated protein kinase, beta-2 subunit , AMPK beta 2 , AMPK beta-2 chain , AMPK subunit beta-2 , AMP-activated protein kinase beta-2 regulatory subunit , AMPK beta-2

380372 Xenopus laevis
457245 Pan troglodytes
512665 Bos taurus
612807 Canis lupus familiaris
699806 Macaca mulatta
100127782 Xenopus (Silurana) tropicalis
100172154 Pongo abelii
100218045 Taeniopygia guttata
5565 Homo sapiens
108097 Mus musculus
64562 Rattus norvegicus
427017 Gallus gallus
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