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PRKAR1A Proteins

(Protein Kinase, CAMP-Dependent, Regulatory, Type I, alpha (Tissue Specific Extinguisher 1) (PRKAR1A))

cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. This gene encodes one of the regulatory subunits. This protein was found to be a tissue-specific extinguisher that down-regulates the expression of seven liver genes in hepatoma x fibroblast hybrids. Mutations in this gene cause Carney complex (CNC). This gene can fuse to the RET protooncogene by gene rearrangement and form the thyroid tumor-specific chimeric oncogene known as PTC2. A nonconventional nuclear localization sequence (NLS) has been found for this protein which suggests a role in DNA replication via the protein serving as a nuclear transport protein for the second subunit of the Replication Factor C (RFC40). Several alternatively spliced transcript variants encoding two different isoforms have been observed. [provided by RefSeq, Jan 2013].

recommended

PRKAR1A Protein (AA 1-381) (GST tag) (ABIN1316241)

PRKAR1A Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA

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recommended

PRKAR1A Protein (AA 1-100) (GST tag) (ABIN1316243)

PRKAR1A Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA

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recommended

PRKAR1A Protein (AA 1-381) (Strep Tag) (ABIN3082471)

Crystallography grade PRKAR1A Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS

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PRKAR1A Proteins by Grade

Find PRKAR1A Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

PRKAR1A Proteins by Origin

Find PRKAR1A Proteins for a variety of species such as anti-Human PRKAR1A, anti-Mouse PRKAR1A, anti-Chicken PRKAR1A. The species listed below are among those available. Click on a link to go to the corresponding products.

PRKAR1A Proteins by Source

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PRKAR1A Proteins by Protein Type

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PRKAR1A Proteins by Application

Find PRKAR1A Proteins validated for a specific application such as ELISA, WB, SDS, AbP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular PRKAR1A Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

PRKAR1A Protein (AA 1-381) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1316241

Quantity 10 μg

Datasheet Datasheet

PRKAR1A Protein (AA 1-100) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1316243

Quantity 10 μg

Datasheet Datasheet

PRKAR1A Protein (AA 1-381) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3082471

Quantity 1 mg

Datasheet Datasheet

PRKAR1A Protein (AA 2-381) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN3082472

Quantity 1 mg

Datasheet Datasheet

PRKAR1A Protein (AA 1-381) (Strep Tag)

Reactivity Mouse

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3129544

Quantity 1 mg

Datasheet Datasheet

PRKAR1A Protein (AA 2-381) (His tag)

Reactivity Mouse

Source Insect Cells

Validations

Cat. No. ABIN3129545

Quantity 1 mg

Datasheet Datasheet

PRKAR1A Protein (His tag)

Reactivity Human

Source Human Cells

Validations

Cat. No. ABIN7318228

Quantity 50 μg

Datasheet Datasheet

PRKAR1A Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2729580

Quantity 20 μg

Datasheet Datasheet

PRKAR1A Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2729581

Quantity 20 μg

Datasheet Datasheet

PRKAR1A Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2729582

Quantity 20 μg

Datasheet Datasheet

PRKAR1A Protein (AA 2-381) (His tag)

Reactivity Human

Source Human Cells

Validations

Cat. No. ABIN7313304

Quantity 50 μg

Datasheet Datasheet

PRKAR1A Protein (His tag)

Reactivity Human

Source Insect cells (Sf9)

Validations

Cat. No. ABIN6700424

Quantity 50 μg

Datasheet Datasheet

PRKAR1A Protein (AA 1-167) (His tag)

Reactivity Golden Syrian Hamster

Source Yeast

Validations

Cat. No. ABIN1609698

Quantity 1 mg

Datasheet Datasheet

PRKAR1A Protein (AA 1-380) (His tag)

Reactivity Cow

Source Yeast

Validations

Cat. No. ABIN1460087

Quantity 1 mg

Datasheet Datasheet

PRKAR1A Protein (AA 1-380) (His tag)

Reactivity Pig

Source Yeast

Validations

Cat. No. ABIN1472631

Quantity 1 mg

Datasheet Datasheet

Aliases for PRKAR1A Proteins

protein kinase cAMP-dependent type I regulatory subunit alpha (PRKAR1A) Proteins
protein kinase, cAMP dependent regulatory, type I, alpha (Prkar1a) Proteins
protein kinase cAMP-dependent type 1 regulatory subunit alpha (Prkar1a) Proteins
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) a (prkar1aa) Proteins
cAMP-dependent protein kinase type I-alpha regulatory subunit pseudogene (LOC707275) Proteins
protein kinase cAMP-dependent type I regulatory subunit alpha (Prkar1a) Proteins
protein kinase cAMP-dependent type I regulatory subunit alpha S homeolog (prkar1a.S) Proteins
1300018C22Rik Proteins
ACRDYS1 Proteins
ADOHR Proteins
CAR Proteins
CNC Proteins
CNC1 Proteins
cnc1 Proteins
im:7047729 Proteins
PKR1 Proteins
pkr1 Proteins
PPNAD1 Proteins
ppnad1 Proteins
PRKAR1 Proteins
prkar1 Proteins
prkar1a Proteins
RIalpha Proteins
RIIA Proteins
Tse-1 Proteins
TSE1 Proteins
Tse1 Proteins
tse1 Proteins
zgc:92515 Proteins

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PRKAR1A Proteins by Grade

PRKAR1A Proteins by Origin

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Popular PRKAR1A Proteins

Aliases for PRKAR1A Proteins

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