CD6 (CD6) (AA 472-668) antibody
| Antigen |
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| Synonyms |
TP120, FLJ44171 |
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Binding Site
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| Clonality |
Monoclonal (6B9) |
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Host
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Reactivity
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Conjugate
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FITC (13), Biotin (12), PE (9), APC (3), Alexa Fluor 647 (3), RPE (3), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), PerCP (1)
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Application
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 Alternatives ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
Flow Cytometry (FACS) (75), Western Blotting (WB) (38), Immunoprecipitation (IP) (34), Immunofluorescence (IF) (23), Immunohistochemistry (IHC) (19), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (18), Immunohistochemistry (Fixed) (IHC (fx)) (11), ELISA (9), Functional Studies (Func) (5), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunohistochemistry (Frozen Sections) (IHC (fro)) (2), Immunoelectron Microscopy (IEM) (1)
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| Catalog no. |
ABIN1098118 |
| Quantity |
0.1ml |
| Price |
396.00 $ Plus shipping costs $45.00
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Bulk discount
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| Shipping to |
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| Availability |
Will be delivered in 3 to 4 Business Days |
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Alternative name
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CD6
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Immunogen
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Purified recombinant fragment of human CD6 (AA: 472-668) expressed in E. Coli.
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Isotype
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IgG1
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Clone
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6B9
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Description
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Synonyms: TP120, FLJ44171.
This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene.
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Molecular Weight
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71.8kDa
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Application Notes
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ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000
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Buffer
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PBS + 0.5% protein stabilizer
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Preservative
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0.05% sodium azide
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Storage
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Store at 4°C, for long term storage, store at -20°C
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Research Area
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CD Antigens, Surface Receptors of Immune Cells
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Restrictions
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For Research Use only
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Product
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Sarrias, Farnós, Mota et al.: "CD6 binds to pathogen-associated molecular patterns and protects from LPS-induced septic shock." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 28, pp. 11724-9, 2007 (PubMed).
Alonso, Buors, Le Dantec et al.: "Aberrant expression of CD6 on B-cell subsets from patients with Sjögren's syndrome." in: Journal of autoimmunity, Vol. 35, Issue 4, pp. 336-41, 2010 (PubMed).
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Alternatives for antigen "CD6 (CD6)", type "Antibodies"
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Hosts
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Mouse (79), Rabbit (25), Rat (1)
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Reactivities
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Human (83), Rat (Rattus) (31), Mouse (Murine) (20), Cow (Bovine) (7), Pig (Porcine) (4), Cat (Feline) (1), Chicken (1), Dog (Canine) (1)
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Applications
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Flow Cytometry (FACS) (75), Western Blotting (WB) (38), Immunoprecipitation (IP) (34), Immunofluorescence (IF) (23), Immunohistochemistry (IHC) (19), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (18), Immunohistochemistry (Fixed) (IHC (fx)) (11), ELISA (9), Functional Studies (Func) (5), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunohistochemistry (Frozen Sections) (IHC (fro)) (2), Immunoelectron Microscopy (IEM) (1)
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Conjugates
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FITC (13), Biotin (12), PE (9), APC (3), Alexa Fluor 647 (3), RPE (3), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), PerCP (1)
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Epitopes
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C-Term (2), Center (2), AA 18-396 (1)
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2013 BioMed Central Research Awards
