LIM Domain Only 2 (Rhombotin-Like 1) (LMO2) (AA 1-158) antibody

Details for Product No. ABIN1098128
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Antigen
Synonyms Rbtn-2, Rbtn2, Rhom-2, Ttg2, RBTN2, RBTNL1, RHOM2, TTG2, wu:fc83a08, zgc:111930, LMO-2, lmo2-A, xlmo2, rhombotin-2
Epitope
AA 1-158
(18), (7), (6), (4), (4), (2), (1), (1)
Reactivity
Human
(91), (16), (15), (13), (13), (12), (3), (1)
Host
Mouse
(51), (45), (3)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB), Fluorescence Microscopy (FM)
(66), (45), (23), (14), (11), (10), (9), (8), (3), (1), (1)
Pubmed 2 references available
Quantity 0.1 mg
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Catalog No. ABIN1098128
396.00 $
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Immunogen Purified recombinant fragment of human LMO2 (AA 1-158) expressed in E. coli.
Clone 4D8
Isotype IgG1
Purification Purified
Alternative Name LMO2
Background Synonyms:
TTG2, RBTN2, RHOM2, RBTNL1
LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms. ,,
Molecular Weight 18.4 kDa
Gene ID 4005
Research Area Cardiovascular
Application Notes Recommended Dilution:
ELISA: Propose dilution 1/10000, WB: 1/500 - 1/2000, FCM: 1/200 - 1/400
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Buffer PBS with 0.05 % sodium azide and 0.5 % protein stabilizer
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Supplier Images
anti-LIM Domain Only 2 (Rhombotin-Like 1) (LMO2) (AA 1-158) antibody Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng)
anti-LIM Domain Only 2 (Rhombotin-Like 1) (LMO2) (AA 1-158) antibody (2) anti-LIM Domain Only 2 (Rhombotin-Like 1) (LMO2) (AA 1-158) antibody (Image 2)
anti-LIM Domain Only 2 (Rhombotin-Like 1) (LMO2) (AA 1-158) antibody (3) Figure 1: Western blot analysis using LMO2 mAb against human LMO2 recombinant protein. (Expected MW is 43.9 kDa)
anti-LIM Domain Only 2 (Rhombotin-Like 1) (LMO2) (AA 1-158) antibody (4) Figure 2: Western blot analysis using LMO2 mAb against HEK293 (1) and LMO2 (AA: 1-158) -hIgGFc transfected HEK293 (2) cell lysate.
Product cited in: Baecklund, Backlin, Mansouri et al.: "LMO2 protein expression predicts survival in patients with rheumatoid arthritis and diffuse large B-cell lymphoma." in: Leukemia & lymphoma, Vol. 52, Issue 6, pp. 1146-9, 2011 (PubMed).

Cubedo, Maurin, Jiang et al.: "PRDM1/Blimp1 downregulates expression of germinal center genes LMO2 and HGAL." in: The FEBS journal, Vol. 278, Issue 17, pp. 3065-75, 2011 (PubMed).

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