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LIM Domain Only 2 (Rhombotin-Like 1) (LMO2) (AA 1-158) antibody

Antigen

LIM Domain Only 2 (Rhombotin-Like 1) (LMO2)
Synonyms TTG2, RBTN2, RHOM2, RBTNL1, wu:fc83a08, zgc:111930, MGC124678, MGC139114
Binding Site
Alternatives

AA 1-158
Clonality Monoclonal (4D8)
Host
Alternatives

Mouse
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives ELISA, Western Blotting (WB), Flow Cytometry (FACS)
2 references available
Catalog no. ABIN1098128
Quantity 0.1mg
Price 396.00 $   Plus shipping costs $45.00
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Additional Information
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Alternative name LMO2
Immunogen Purified recombinant fragment of human LMO2 (AA: 1-158) expressed in E. Coli.
Isotype IgG1
Clone 4D8
Description Synonyms: TTG2, RBTN2, RHOM2, RBTNL1.
LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.
Molecular Weight 18.4kDa

Application Details
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Application Notes ELISA: 1/10000, WB: 1/500 - 1/2000, FCM: 1/200 - 1/400
Buffer PBS + 0.5% protein stabilizer
Preservative 0.05% sodium azide
Storage Store at 4°C, for long term storage, store at -20°C
Research Area Cardiovascular
Restrictions For Research Use only

Publications
Application Details Alternatives back to top

Product Baecklund, Backlin, Mansouri et al.: "LMO2 protein expression predicts survival in patients with rheumatoid arthritis and diffuse large B-cell lymphoma." in: Leukemia & lymphoma, Vol. 52, Issue 6, pp. 1146-9, 2011 (PubMed).

Cubedo, Maurin, Jiang et al.: "PRDM1/Blimp1 downregulates expression of germinal center genes LMO2 and HGAL." in: The FEBS journal, Vol. 278, Issue 17, pp. 3065-75, 2011 (PubMed).

Alternatives
Application Details Publications back to top

Alternatives for antigen "LIM Domain Only 2 (Rhombotin-Like 1) (LMO2)", type "Antibodies"
Hosts Rabbit (27), Mouse (11), Sheep (3)
Reactivities Human (40), Mouse (Murine) (21), Rat (Rattus) (20), Chicken (19), Cow (Bovine) (19), Dog (Canine) (18), Horse (Equine) (18), Xenopus laevis (1)
Applications Immunofluorescence (IF) (19), Western Blotting (WB) (18), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (15), ELISA (6), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunoprecipitation (IP) (3), Flow Cytometry (FACS) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (IHC) (1)
Conjugates Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE-Cy3 (1), PE-Cy5 (1), PE-Cy5.5 (1), PE-Cy7 (1), Un-conjugated (1)
Epitopes C-Term (2), N-Term (2)