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Details for Product No. ABIN1098128

LIM Domain Only 2 (Rhombotin-Like 1) (LMO2) (AA 1-158) antibody

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Antigen
Synonyms wu:fc83a08, zgc:111930, LMO-2, lmo2-A, xlmo2, TTG2, RBTN2, RHOM2, RBTNL1, Rbtn-2, Rbtn2, Rhom-2, Ttg2, rhombotin-2
Epitope
»Alternatives AA 1-158
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Western Blotting (WB), Fluorescence Microscopy (FM)
Pubmed 2 references available
Catalog no. ABIN1098128
Quantity 0.1 mg
Price
396.00 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 3 to 4 Business Days
Immunogen Purified recombinant fragment of human LMO2 (AA 1-158) expressed in E. coli.
Clone 4D8
Isotype IgG1
Purification Purified
Alternative Name LMO2
Background Synonyms:
TTG2, RBTN2, RHOM2, RBTNL1
LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms. ,,
Molecular Weight 18.4 kDa
Gene ID 4005
Research Area Cardiovascular
Application Notes Recommended Dilution:
ELISA: Propose dilution 1/10000, WB: 1/500 - 1/2000, FCM: 1/200 - 1/400
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Buffer PBS with 0.05 % sodium azide and 0.5 % protein stabilizer
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Product cited in: Baecklund, Backlin, Mansouri et al.: "LMO2 protein expression predicts survival in patients with rheumatoid arthritis and diffuse large B-cell lymphoma." in: Leukemia & lymphoma, Vol. 52, Issue 6, pp. 1146-9, 2011 (PubMed).

Cubedo, Maurin, Jiang et al.: "PRDM1/Blimp1 downregulates expression of germinal center genes LMO2 and HGAL." in: The FEBS journal, Vol. 278, Issue 17, pp. 3065-75, 2011 (PubMed).

Alternatives for antigen "LIM Domain Only 2 (Rhombotin-Like 1) (LMO2)", type "Antibodies"
Hosts (45), (45), (3)
Reactivities (87), (19), (18), (17), (13), (13), (4), (1), (1), (1), (1), (1), (1)
Applications (57), (48), (16), (15), (14), (10), (8), (7), (5), (2), (2), (1), (1)
Conjugates (4), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (6), (5), (4), (3), (2)
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