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human Splunc2 (AA 16-250) antibody
ELISA, Western Blotting (WB), Flow Cytometry (FACS)
|2 references available|
|Price||396.00 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 3 to 4 Business Days|
|Immunogen||Purified recombinant fragment of human Splunc2 (AA: 16-250) expressed in E. Coli.|
Synonyms: BPIFA2, PSP, SPLUNC2, C20orf70, bA49G10.1.
SPLUNC2 is one member of PLUNC family, the gene undergoes alternative splicing using two 5' non-coding exons, suggesting that the gene is regulated by alternative promoters.multiple SPLUNC2 isoforms are found in the oral cavity and suggest that these proteins may be differentially regulated in distinct tissues where they may function in the innate immune response. Mucin plugs, mucous and intermediate cells of mucoepidermoid carcinomas were positive for LPLUNC1 and SPLUNC2, but areas composed of epidermoid and clear cells were negative for all PLUNCs. Papillary cystadenocarcinoma was positive for all PLUNCs.
|Application Notes||ELISA: 1/10000, WB: 1/500 - 1/2000, FCM: 1/200 - 1/400|
|Buffer||PBS + 0.5% protein stabilizer|
|Preservative||0.05% sodium azide|
|Storage||Store at 4°C, for long term storage, store at -20°C|
|Restrictions||For Research Use only|
Vargas, Speight, Bingle et al.: "Expression of PLUNC family members in benign and malignant salivary gland tumours." in: Oral diseases, Vol. 14, Issue 7, pp. 613-9, 2008 (PubMed).
Bingle, Barnes, Lunn et al.: "Characterisation and expression of SPLUNC2, the human orthologue of rodent parotid secretory protein." in: Histochemistry and cell biology, Vol. 132, Issue 3, pp. 339-49, 2009 (PubMed).