CCL2 antibody

Catalog No. ABIN110555

The Rabbit Polyclonal anti-CCL2 antibody is suitable to detect CCL2 in samples from Rat. It has been validated for WB.

Quick Overview for CCL2 antibody (ABIN110555)

Target: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CCL2 Antibody

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Storage: 4 °C

Target Details for CCL2

Target: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Alternative Name: MCP-1(Monocyte Chemoattractant Protein-1)

Background: Rat MCP-1/JE (monocyte chemoattracctant protein-1) is a 148-amino acid CC chemokine with a NH2-terminal sequence of 29 residues as a signal sequence. It was originally cloned from Con A-stimulated rat spleen cDNA library1. This rat MCP-1/JE is 49-amino acid longer than human MCP-1 at 3?-end. This 3?-end is a serine and threonine rich zone, which is probably responsible for the extensive O- glycosylation and explains for the higher molecular weight (25 kDa)2. In vitro, MCP-1/JE is chemotactic for monocytes as well as lymphocytes and basophils, but not for neutrophils. MCP-1/JE is produced by a wide range of cell types as a reaction to diverse inflammatory stimuli3.

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, The Global Phosphorylation Landscape of SARS-CoV-2 Infection