ITGB1 antibody (PE)

Catalog No. ABIN1106236

This Mouse Monoclonal antibody specifically detects ITGB1 in FACS. It exhibits reactivity toward Human.

Quick Overview for ITGB1 antibody (PE) (ABIN1106236)

Target: ITGB1 (Integrin beta 1 (ITGB1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ITGB1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: AG89

Product Details anti-ITGB1 Antibody (PE)

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Protein A agarose

Immunogen: G-361 Human melanoma cell line

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS, 0.09 % NaN3, 1 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2 - 8 °C.

Target Details for ITGB1

Target: ITGB1 (Integrin beta 1 (ITGB1))

Alternative Name: CD29 / Integrin beta-1

Background: The integrin family of adhesion molecules participates in important cell-cell and cellextracellular matrix interactions in a diverse range of biological processes. Integrins are heterodimers consisting of a a subunit and ß subunit. Both a and ß subunit are transmembrane proteins with large extracellular domains (>100 kDa for a subunit and >75 kDa for ß subunit) that interact with extracellular matrix proteins and relatively small cytoplasmic domains (50 amino acids or less, except for the ß4 subunit) that interact with cytoskeletal proteins. The adhesiveness of integrins is dynamically regulated in response to cytoplasmic signals, termed Synonyms: FNRB, Fibronectin receptor subunit beta, ITGB1, Integrin VLA-4 subunit beta, MDF2, MSK12

Gene ID: 9606

UniProt: P05556

Pathways: Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome