Claudin 17 antibody (Middle Region)

Catalog No. ABIN1106719

This Rabbit Polyclonal antibody specifically detects Claudin 17 in WB and IHC (p). It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow and Pig.

Quick Overview for Claudin 17 antibody (Middle Region) (ABIN1106719)

Target: Claudin 17 (CLDN17)

Reactivity: Human, Mouse, Rat, Dog, Cow, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 17 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Claudin 17 Antibody

Binding Specificity: Middle Region

Sequence: KQVQCTGSNE RAKAYLLGTS GVLFILTGIF VLIPVSWTAN IIIRDFYNPA

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Dog, Pig, BovineSpecies reactivity (tested):Human

Purification: Purified using Protein A affinity column

Immunogen: The immunogen for anti-CLDN17 antibody: synthetic peptide directed towards the middle region of human CLDN17

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Add 100 μL of distilled water to a final concentration of 1 mg/mL.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Target Details for Claudin 17

Target: Claudin 17 (CLDN17)

Alternative Name: Claudin-17 / CLDN17

Background: CLDN17, clustered with CLDN8 at human chromosome 21q22.11, is a four-transmembrane protein with WWCC motif, defined by W-X(17-22)-W-X(2)-C-X(8-10)-C. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.Synonyms: PRO1489, UNQ758

Gene ID: 26285

NCBI Accession: NP_036263

Pathways: Cell-Cell Junction Organization, Hepatitis C