DBP antibody (Middle Region)

Catalog No. ABIN1106957

The Rabbit Polyclonal anti-DBP antibody is suitable to detect DBP in samples from Human, Rat, Mouse, Dog and Cow. It has been validated for WB and IHC (p).

Quick Overview for DBP antibody (Middle Region) (ABIN1106957)

Target: DBP (D Site of Albumin Promoter (Albumin D-Box) Binding Protein (DBP))

Reactivity: Human, Rat, Mouse, Dog, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DBP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-DBP Antibody

Binding Specificity: Middle Region

Sequence: SSPGHAPARA ALGTASGHRA GLTSRDTPSP VDPDTVEVLM TFEPDPADLA

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Dog, Bovine, SheepSpecies reactivity (tested):Human

Purification: Purified on peptide immunoaffinity column

Immunogen: The immunogen for anti-DBP antibody: synthetic peptide directed towards the middle region of human DBP

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Add 50 μL of distilled water

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the lyophised antibody at -20 °C for up to one year. Store reconstitued antibody undiluted for one month or in aliquots at -20 °C long term.

Expiry Date: 12 months

Target Details for DBP

Target: DBP (D Site of Albumin Promoter (Albumin D-Box) Binding Protein (DBP))

Alternative Name: DBP

Background: This transcriptional activator recognizes and binds to the sequence 5'-RTTAYGTAAY-3' found in the promoter of genes such as albumin, CYP2A4 and CYP2A5. It is not essential for circadian rhythm generation, but modulates important clock output genes. May be a direct target for regulation by the circadian pacemaker component clock. May affect circadian period and sleep regulation. DBP is a member of the PAR bZIP (proline and acidic amino acid-rich basic leucine zipper) transcription factor family.Synonyms: Albumin D box-binding protein, Albumin D-element-binding protein, D site of albumin promoter (albumin D-box) binding protein, D site-binding protein, DABP, TaxREB302

Gene ID: 1628

NCBI Accession: NP_001343