MYEF2 antibody (Middle Region)

Catalog No. ABIN1108332

Product Details anti-MYEF2 Antibody

Target: MYEF2 (Myelin Expression Factor 2 (MYEF2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio), Chicken, Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYEF2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Sequence: QAGRLGSTIF VANLDFKVGW KKLKEVFSIA GTVKRADIKE DKDGKSRGMG

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Dog, Chicken, Bovine, African clawed frog, ZebrafishSpecies reactivity (tested):Human

Purification: Purified using peptide immunoaffinity column

Immunogen: The immunogen for anti-MYEF2 antibody: synthetic peptide directed towards the middle region of human MYEF2.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Target Details for MYEF2

Target: MYEF2 (Myelin Expression Factor 2 (MYEF2))

Alternative Name: MyEF-2 (MYEF2 Products)

Background: MYEF-2 is expressed early in the differentiation program and is suppressed by specific polypeptide growth factors. The ability of MYEF-2 to recognize conserved activating elements associated with multiple-specific genes suggests that this factor may participate in the coordinate regulation of genes during myogenesis. MYEF1 acts as transcriptional repressor of the myelin basic protein gene (MBP) and binds to the proximal MB1 element 5'-TTGTCC-3' of the MBP promoter. Its binding to MB1 and function are inhibited by PURA.Synonyms: KIAA1341, MST156, MYEF2, Myelin expression factor 2

Gene ID: 50804

NCBI Accession: NP_057216